A5070918864- Vitamin D Research Studies
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- IL-33, ST2, and ILC Pathways
- Maternal Mental Health During Pregnancy and Postpartum
- SARS-CoV-2 and COVID-19 Research
- Contact Dermatitis and Allergies
- Vaccine Coverage and Hesitancy
- Clinical practice guidelines implementation
- COVID-19 Clinical Research Studies
- Dermatology and Skin Diseases
- Menstrual Health and Disorders
- Telemedicine and Telehealth Implementation
- Tryptophan and brain disorders
- Nutrition, Genetics, and Disease
- Global Healthcare and Medical Tourism
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Stress Responses and Cortisol
Lithuanian University of Health Sciences
2024
Bronchial asthma (BA) exhibits varying prevalence across global populations, prompting a comprehensive investigation into genetic and environmental determinants. Vitamin D is potent immunomodulator capable of suppressing inflammatory signals in several cell types involved the asthmatic response; it exerts effects on immune system by binding to nuclear vitamin receptor (VDR). VDR gene variations are affecting serum levels with possible role BA risk. The current study aimed examine complex...
Background: In order to improve the control of atopic diseases, it is important clarify pathogenesis atopy and identify its various triggers. Single nucleotide polymorphisms (SNPs) vitamin D receptor gene (VDR) may impact atopy. The aim this study was investigate possible associations between VDR SNPs D, total IgE, eosinophils in Methods: total, 203 adults, including 122 patients with diseases (45 dermatitis, 77 allergic asthma) 81 healthy controls, were involved study. blood eosinophil...
Atopic diseases, including atopic dermatitis (AD) and allergic asthma (AA), are characterized by complex immune responses involving various T cells subsets their cytokine profiles. It is assumed that single nucleotide polymorphisms (SNPs) in the Vitamin D receptor (VDR) gene D-binding protein (GC) related to action of and, consequently, play a role regulating response. However, there not enough data unequivocally support hypothesis about relationship between profile VDR or GC SNPs. Two...
Background and Objectives: Vaccination is one means of SARS-CoV-2 prevention control. However, despite the effectiveness vaccination, adverse reactions continue to require vigilance monitoring. The researchers emphasize possibility that some reported side effects may be psychological in origin. Based on this hypothesis, main goal study was evaluate emotional dispositions healthcare workers who experienced emotions before vaccination after vaccination. Materials Methods: This conducted...
In the global threat of SARS-CoV-2, individuals undergoing maintenance dialysis represent a vulnerable population with an increased risk severe COVID-19 outcomes. Therefore, immunization against SARS-CoV-2 is essential component healthcare strategy for these patients. Existing data indicate that they tend to exhibit reduced immune response vaccines compared general population. Our study aimed assess both humoral and cellular responses following two doses anti-SARS-CoV-2 mRNA vaccine, ability...
T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved inflammation. The aim is to evaluate cytokine level before after nasal challenge with Dermatophagoides pteronyssinus patients AAD.
Introduction It is known that symptoms of major depressive disorder (MDD) are associated with neurodegeneration, lipopolysaccharide (LPS) can induce MDD, and blood LPS levels elevated in neurodegeneration. However, it not whether cytokine correlate cognition brain structure, this tested study. Methods analysis This cross-sectional study includes individuals MDD ( n = 100) a control group no one-year history mental 50). A comprehensive evaluation performed, including the collection basic...
Non-specific Lipid Transfer proteins (nsLTPs) are relevant allergens of several pollens and plant foods. Sensitization to nsLTPs is not typical in our region. Still, it has become an increasingly common cause IgE-mediated food allergies food-induced anaphylaxis Northern Europe recent decades. No in-depth studies describe the prevalence sensitization molecular components Lithuania. This study aimed determine profile atopic patients at Immunology Allergy Department Kauno Klinikos nsLTPs, using...