- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Conducting polymers and applications
- Fuel Cells and Related Materials
- Silicone and Siloxane Chemistry
- Marine Bivalve and Aquaculture Studies
- Synthesis and properties of polymers
- Advanced Battery Materials and Technologies
- Perovskite Materials and Applications
- Graphene research and applications
- Epoxy Resin Curing Processes
- Flood Risk Assessment and Management
- Viral Infections and Immunology Research
- T-cell and Retrovirus Studies
- Nanoporous metals and alloys
- Artificial Intelligence in Healthcare and Education
- Advanced Polymer Synthesis and Characterization
- Disaster Management and Resilience
- interferon and immune responses
- Coral and Marine Ecosystems Studies
- Copper-based nanomaterials and applications
- Carbon Nanotubes in Composites
- Advanced Sensor and Energy Harvesting Materials
- Mesoporous Materials and Catalysis
- Nanopore and Nanochannel Transport Studies
Second Affiliated Hospital of Nanjing Medical University
2022-2025
Affiliated Hospital of Hangzhou Normal University
2024
Qingzhou City People's Hospital
2024
Shanghai Jiao Tong University
2008-2023
Huazhong University of Science and Technology
2023
East China Normal University
2019-2023
Ocean University of China
2023
Stony Brook University
2023
State University of New York
2023
Fudan University
2023
Previous studies have shown that the nicotinamide adenine dinucleotide (NAD+) precursors, mononucleotide (NMN) and riboside (NR), protect against endogenously or exogenously induced DNA damage. However, whether two compounds same different efficacy damage is not clear. In current study, we systematically compared effects of NMN NR on cisplatin-induced in HeLa cells. To evaluate protective NR, cells were pretreated with doses followed 10 μM cisplatin treatment. Cell viability was examined by...
Multiwalled carbon nanotubes (MWNTs) have been widely used as mechanical reinforcement agents in the past few years. However, enhancement of properties composites has greatly hampered by its limited available interface area composites. Toward solving this intrinsic limitation MWNTs, paper, we report use unzipped MWNTs (uCNTs) nanofillers for polymer first time. The uCNTs were produced an oxidative unzipping process, involving lengthwise cutting and opening walls yielded separated ribbonlike...
We here demonstrate a facile approach of one-step to obtain the complex wrinkling patterned surface photocuring coating by using thiol and fluorocarbon chains containing POSS (F2-POSS-SH6) as reactive nanoadditive. F2-POSS-SH6 can self-assemble into top layer UV-curing liquid resin. As result, mismatch shrinkage caused different types photo-cross-linking reaction between bulk leads formation pattern. The characteristic wavelength (λ) amplitude (A) are linearly dependent on concentration...
Introduction Psoriasis is a common inflammatory skin disease recognized by the World Health Organization as "an incurable chronic, noninfectious, painful, disfiguring and disabling disease." The fact that metabolic syndrome (MetS) most important comorbidities of psoriasis suggests an role lipid metabolism in pathogenesis psoriasis. Narciclasine (Ncs) alkaloid isolated from Amaryllidaceae plants. Its biological activities include antitumor, antibacterial, antiinflammatory, anti-angiogenic...
In response to the increasing public awareness of serious dye-contained wastewater contamination, we herein fabricated a novel anthracene-containing hyperbranched poly(ether amine) (hPEA-AN)/carbon nanotube (CNT) ultrathin membrane (UTM), which combined both merits conventional dye adsorption strategy and filtration process, implement efficient selective molecules also separation mixtures by molecular filtration. Taking advantage π–π stacking interactions between anthracene CNT sidewalls...
Cardiac dysfunction is manifested as decline of cardiac systolic function, and multiple cardiovascular diseases (CVDs) can develop insufficiency. Mitochondrial antiviral signaling (MAVS) known an innate immune regulator involved in viral infectious autoimmune diseases, whereas its role the heart remains obscure. The alteration MAVS was analyzed animal models with non-hypertrophic hypertrophic dysfunction. Then, MAVS-deficient mice were generated to examine mitochondrial status energy...
Molecular filtration is very attractive in the industrial applications of separation and water treatment, but it challenging to realize fast due low transport rates filtrate loss within membranes commercial ultrafiltration. We here demonstrated a novel example that nanofiber membrane poly(ether amine) (PEA) can be used hydrophilic dyes through molecular filtration. Two types PEA (PEA-NF) were fabricated electrospinning process, which further photo-crosslinked UV-induced dimerization coumarin...
Generalized arterial calcification of infancy (GACI) is a rare genetic disease characterized by calcifications or stenoses and hypertension. GACI caused mutations in the ENPP1 ABCC6 genes, it often causes intrauterine early death. Here, we report case homozygous variation ENPP1, Chinese infant initially presenting with The proband was an 8-month-old boy utero tricuspid valve calcification, hypertension at birth. Enhanced computed tomography revealed extensive calcification. Genetic testing...
Multi-micelle aggregation (MMA) mechanism is widely acknowledged to explicate large spherical micelles self-assembly, but the process of MMA during self-assembly hard observe. Herein, a novel kind strong, regular microspheres fabricated from amphiphilic anthracene-functionalized β-cyclodextrin (CD-AN) via Cu(I)-catalyzed azide-alkyne click reactions reported. The obtained CD-AN amphiphiles can self-assemble in water primary core-shell secondary aggregates with diameter changing several tens...
Open AccessCCS ChemistryRESEARCH ARTICLE1 Aug 2020Toward the Highly Ordered Lamellar Hybrid Membrane for Molecular Sieving by One-Pot Self-Assembly of Hyperbranched Polymer Jin Li, Zhilong Su, Xiaodong Ma, Jie Yin and Xuesong Jiang Li School Chemistry & Chemical Engineering, Frontiers Science Center Transformative Molecules, State Key Laboratory Metal Matrix Composite Materials, Shanghai Jiao Tong University, 200240 , Su Ma *Corresponding author: E-mail Address: [email protected]...
Objective: To evaluate the effects of long-term wear and discontinuation orthokeratology lenses (Orth-K) on biological parameters eyeballs in children with myopia. Methods: In this prospective study, a total 308 subjects myopia were randomized to receive Orth-K (n = 154) or single vision spectacles (SVS) for 12 months followed by 1-month withdrawal period. The axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD) lens (CLT) assessed at baseline, 6 months, 13...
We demonstrated here novel multistimuli responsive organosilica hybrid nanopaticles (SiO1.5-gPEA NPs) based on graft poly(ether amine)s (gPEAs). Poly(ether comprised of trimethoxysilyl moieties (TMS-gPEAs) were synthesized via nucleophilic substitution/ring-opening reaction commercial poly(propylene glycol) diglycidyl ether, Jeffamine L100 and 2-aminoethanolthiol, followed by introducing (TMS) into side-chain "thiol−ene" reaction. The obtained TMS-gPEAs could be dispersed directly in water...
Mutations near allosteric sites can have a significant impact on the function of KRAS. Three specific mutations, K104Q, G12D/K104Q, and G12D/G75A, which are located positions, were selected to investigate molecular mechanisms behind mutation-induced influences activity Gaussian accelerated dynamics (GaMD) simulations followed by principal component analysis (PCA) performed improve sampling conformational states. The results revealed that these mutations significantly alter structural...