- Cardiovascular Issues in Pregnancy
- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Antifungal resistance and susceptibility
- Autophagy in Disease and Therapy
- Cardiovascular Disease and Adiposity
- Renal Transplantation Outcomes and Treatments
- Aortic Disease and Treatment Approaches
- Cannabis and Cannabinoid Research
- Cervical and Thoracic Myelopathy
- Uterine Myomas and Treatments
- Peripheral Neuropathies and Disorders
- Aortic aneurysm repair treatments
- Peptidase Inhibition and Analysis
- Cerebrovascular and Carotid Artery Diseases
- Coffee research and impacts
- Advanced MRI Techniques and Applications
- Coronary Artery Anomalies
- Polyamine Metabolism and Applications
- Pregnancy and preeclampsia studies
- Gynecological conditions and treatments
University of Saskatchewan
2024-2025
Beijing Anzhen Hospital
2017-2025
Capital Medical University
2017-2025
St. Paul's Hospital
2025
St. Paul's Hospital
2024-2025
Saskatchewan Health
2024
Saskatchewan Health Authority
2024
Chinese PLA General Hospital
2022-2024
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2024
Nankai University
2019-2023
ABSTRACT The novel allele HLA‐C*01:282 has a single non‐synonymous mutation compared to HLA‐ C*01:02:01:01 in codon 100 Exon 3.
HLA-DPA1*02:01:34 differs by a single synonymous mutation compared to HLA-DPA1*02:01:01:02 in codon 212 Exon 4.
ABSTRACT The novel allele HLA‐DQB1*02:02:01:14 differs from HLA‐DQB1*02:02:01:01 by one nucleotide substitution in codon 233 exon 5.
ABSTRACT The novel allele HLA‐DPB1*1327:01 has a non‐synonymous mutation difference compared with HLA‐DPB1*04:01:01.
This was a retrospective study that evaluated total of 280 patients who underwent surgery for complete removal endometriosis to develop and validate the predictive model stage IV endometriosis. The differences between I-III were performed by logistic regression. A prediction constructed, which subsequently validated. independent variables visual analogue scale (VAS)≥4 [3.855, 95% confidence interval (CI): 1.675-8.871, p = 0.002], painful nodularity on uterosacral ligaments (13.954, CI:...
Prior studies identified iron deposition in deep brain nuclei and the periaqueductal gray matter region chronic migraine, less is known about cerebral over whole CM. The aim of this case-control study to investigate CM using an advanced quantitative susceptibility mapping.A multi-echo gradient echo MR sequence was used obtain raw mapping data from 12 patients 18 normal controls were reconstructed. Three dimensional T1 images segmented mask generated extract value brain. independent t test...
The modification of chromatin by histone deacetylases (HDACs) has critical roles in transcriptional regulation. In this study, we identified the Rpd3 HDAC complex component Pho23 Candida albicans and explored its role regulation physiological processes. PHO23 deletion increased autophagic activity upregulated transcription ATG genes. Moreover, severely impaired cell wall stress resistance reduced integrity (CWI) pathway response to stress. Furthermore, pho23Δ/Δ mutant had partial defects...
Introduction: Although iron deposition has been identified as a significant migraine trigger, the key structures in episodic (EM) remain unknown. Objective: The aim of this study is to investigate cerebral EM using an advanced voxel-based quantitative susceptibility mapping (QSM). Methods: A multi-echo gradient echo sequence MR was performed 15 patients (EMs) and 27 normal control subjects (NCs). reconstructed images analysis were over entire brain. value all brain regions with altered...
Spinal cord injury without fracture dislocation (SCIWORA) is relatively rare, and spastic paralysis for more than 2 months with Diffuse diopathic skeletal hyperoseosis (DISH) even rarer.
Abstract Patients with complex congenital heart disease (CCHD) may pose a serious threat to the mother-infant safety. This study intends explore influencing factors for adverse pregnancy outcomes in CCHD population. Totally 108 patients who terminated from January 2013 2023 were recruited. We collected clinical data during electronic medical records. Among them, 45 had (41.7%) and no patient died. 5 newborn. The incidence rate of was significantly higher brain natriuretic peptide (BNP) >...
To identify genetic variants associated with Stanford A thoracic aortic aneurysm and dissection (ATAAD) using whole-exome sequencing (WES) analyze positive mutation rates among patients of different onset ages.
Transient receptor potential (TRP) channel Yvc1 was related with hyphal growth, oxidative stress response, and pathogenicity. Calcineurin subunit Cnb1 activated immediately in yeasts when exposed to severe stimulation. However, the relationship between Cnb1-governed calcium ions endoplasmic reticulum (ER) response remains unrevealed. In this study, we found that mutant cnb1 Δ/Δ sensitive TN, which overexpression of membrane ion channels could increase cytosol concentration. growth yvc1...
Objective To evaluate the potential correlation between coronary artery tortuosity caused by myocardial bridge and atherosclerosis. Methods The data of 88 patients with suspected heart disease in Affiliated Hospital North China University Science Technology during period from March 2015 to June 2016 were retrospectively analyzed.Coronary was diagnozed computed tomography angiography.Meanwhile,the contemporary diagnosed without selected as control group.The atherosclerosis well stenosis...
Background: Aortic stenosis (AS) is one of the degenerative heart lesions mainly resulting from congenital defects and rheumatic diseases. This study aimed to determine maternal fetal outcomes in pregnant women with moderate severe AS. Methods: The clinical data 26 AS treated between 2007 2019 Beijing Anzhen Hospital were collected retrospectively analyzed. Results: was diagnosed before pregnancy or after 16 (61.5%) 10 (38.5%) patients, respectively. Except peak velocity mean pressure...
The diagnosis of atypical cystic meningioma is difficult because the MRI findings.This paper reported a case and described detailed findings,which would provide valuable imaging evidence for localization classification meningioma.
Objective: To study the risk assessment, method selection and clinical management of pregnancy termination during first second trimester pregnant women with cardiovascular disease. Methods: This focused on diseases who were admitted to Beijing Anzhen Hospital from January 2016 September 2019, summarize their characteristics, reasons methods termination, outcomes. Results: Among 167 women, 119 cases (71.3%, 119/167) in early 48 (28.7%, 48/167) middle pregnancy. The for disease (109 cases;...