A5101836227- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Cells and Metastasis
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Single-cell and spatial transcriptomics
- Pulmonary Hypertension Research and Treatments
- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Inhalation and Respiratory Drug Delivery
- Antimicrobial agents and applications
- Covalent Organic Framework Applications
- Ectopic Pregnancy Diagnosis and Management
- Circular RNAs in diseases
- Aortic Thrombus and Embolism
- Autophagy in Disease and Therapy
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Endometrial and Cervical Cancer Treatments
- TGF-β signaling in diseases
- Wnt/β-catenin signaling in development and cancer
Chengdu Medical College
2025
Novel (United States)
2025
Beijing Anzhen Hospital
2013-2024
Capital Medical University
2013-2024
Guilin Medical University
2024
Zhengzhou University
2023
Henan Provincial People's Hospital
2023
Wenzhou Medical University
2021
First Affiliated Hospital of Wenzhou Medical University
2021
Hebei Medical University
2017-2018
Background: Systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) are novel inflammatory markers based on neutrophil, platelet lymphocyte counts. Atherosclerosis is a chronic vascular disease. This study aimed to verify the predictive value of clinical parameters such as systemic for severity in Large Artery (LAA) stroke patients. Methods: The SII defined × (neutrophil count/lymphocyte count), NLR neutrophil count. Univariate logistic regression was used analyze...
Objective:To evaluate the clinical effectiveness of laparoscopic management cesarean scar pregnancy (CSP) by deep implantation.Background:A implanting within from a previous delivery is rare condition ectopic pregnancy. There are two different types CSPs. Type I caused implantation amniotic sac on with progression toward either cervicoisthmic space or uterine cavity. II (CSP-II) into CS defect infiltrating growth myometrium and bulging serosal surface, which may result in rupture severe...
Cluster of differentiation 146 (CD146) is an endothelial cell adhesion molecule which overexpressed in various types malignant cancer, including ovarian cancer. However, whether CD146 another two gynecological cervical cancer and endometrial remains unclear. In the present study, we showed that expression levels were higher cells from compared with their corresponding normal tissues, using anti-CD146 mouse antibody AA4 (mAb AA4) mAb exhibited a high performance for specificity, sensitivity...
Abstract Epigenetic information regulates gene expression and development. However, our understanding of the evolution epigenetic regulation on brain development in primates is limited. Here, we compared chromatin accessibility landscapes transcriptomes during fetal prefrontal cortex (PFC) between rhesus macaques humans. A total 304,761 divergent DNase I-hypersensitive sites (DHSs) are identified humans, although many these share conserved DNA sequences. Interestingly, most cis -elements...
Corticotropin-releasing factor (CRF) and its receptors have been detected in numerous tumors an important role tumorigenesis proliferation. However, the of these peptides has not established human glioma malignant cell lines. The present study evaluated for first time, expression CRF receptor 1 (CRFR1) 35 samples, 13 normal brain tissues U87 cells using immunohistochemistry, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) western blot analysis. Levels CRFR1 were...
Abstract Objective: This study aims to investigate the relationship between serum vitamin D, total IgE levels and chronic spontaneous urticaria (CSU). Methods: We collected data from 101 patients with (experimental group) 115 healthy normal subjects (control in same period of physical examination. Results: The results showed that number deficient absolute 25-hydroxyvitamin D experimental group was significantly lower than control ( P < 0.05). Pearson correlation analysis activity score...
Increasing research has shown that the abnormal expression of circRNAs is closely related to tumorigenesis, apoptosis, and patient prognosis in cervical cancer.This study aimed reveal procancer role circIL21R cancer investigate its molecular mechanisms.Bioinformatics analysis revealed promotes progression via miR-1205/PTBP1 axis.CircIL21R was significantly greater tumor tissue than adjacent normal tissue, higher indicated shorter survival.We applied MTS assays, EdU Transwell assays show...
The degree of inflammation and immune status is widely recognized to be associated with intrahepatic cholangiocarcinoma (ICC) closely linked poor postoperative survival. purpose this study was evaluate whether the systemic immune-inflammatory index (SII) albumin bilirubin (ALBI) grade together exhibit better predictive strength compared SII ALBI separately in patients ICC undergoing curative surgical resection.A retrospective analysis performed on a cohort 374 histologically confirmed who...
The aim of this study was to define the pregnancy outcomes in women with congenitally corrected transposition great arteries (cc-TGA). medical databases at Anzhen Hospital between January 2011 and March 2018 were retrospectively reviewed. Data 12 pregnant cc-TGA collected. One patient lost 35 weeks gestation. There 8 (72.7%) term births 3 (27.3%) premature births. Of 11 deliveries, 2 (18.2%) vaginal 9 (81.8%) cesarean. baseline New York Heart Association (NYHA) functional class I - II...
Background: Aortic stenosis (AS) is one of the degenerative heart lesions mainly resulting from congenital defects and rheumatic diseases. This study aimed to determine maternal fetal outcomes in pregnant women with moderate severe AS. Methods: The clinical data 26 AS treated between 2007 2019 Beijing Anzhen Hospital were collected retrospectively analyzed. Results: was diagnosed before pregnancy or after 16 (61.5%) 10 (38.5%) patients, respectively. Except peak velocity mean pressure...