A5003165665- Synthesis and biological activity
- Bioactive Compounds and Antitumor Agents
- Molecular Sensors and Ion Detection
- Analytical Chemistry and Sensors
- Biometric Identification and Security
- Multicomponent Synthesis of Heterocycles
- Synthesis and Biological Evaluation
- Face recognition and analysis
- Microbial Metabolites in Food Biotechnology
- Electrochemical sensors and biosensors
- Curcumin's Biomedical Applications
- Probiotics and Fermented Foods
- Gut microbiota and health
- Enzyme function and inhibition
- Computational Drug Discovery Methods
In this work, the multifunctional potential of four 3-acetylcoumarin derivatives was studied. The were significantly active against bacteria Staphylococcus aureus, Pseudomonas aeoginosa and fungal strain Candida albicans. results antioxidant activity assays promising when compared to ascorbic acid. in vitro anticancer carried out using MTT assay on human cancer cell line COLO-205 3ACDT showed commendable antiproliferative along with appreciable tumor selectivity distinct index. Moreover,...
Abstract This study outlines the synthesis of pyrazine sulfonamides ( 3 a – i ) along with halo‐phenyl derivatives 4 j and 5 e ). The antiproliferative effects were tested against MCF‐7 breast cancer, colon carcinoma HT‐29, HCT‐116 WT, p53 knock‐out mutant cell lines. Compounds b c notably active WT cells, while h moderately effective cells. Among sulfonamides, 4e 4j was most promising compounds evaluated non‐tumorigenic demonstrating cancer selectivity. b, c, e, , showed dose‐dependent...
Probiotic microorganisms play a significant role in promoting gut health. Identifying and characterizing these organisms is very crucial for developing new paths therapeutic research. Screening of potential probiotic from different curd samples to evaluate its antagonistic free radical scavenging activity approach. A total 40 were isolated using MRS agar under microaerophilic conditions. Based on Gram staining, motility, endospore formation, 13 isolates selected further analysis. Catalase...
We report the synthesis, spectroscopic characterization, molecular docking and biological evaluation of nine pyrazino-imidazolinone derivatives. These derivatives were evaluated for their anticancer activity against three cancer cell lines: 518A2 melanoma, HCT-116, HCT-116 p53 knockout mutant colon carcinoma. The MTT assay was employed to assess effectiveness. Among compounds tested, four (5 a, 5 d, g, h) exhibited promising antiproliferative specifically p53-negative cells (IC50 0.23, 0.20,...
Abstract: In forensic science, it is seen that hand-drawn face sketches are still very limited and time consuming when comes to using them with the latest technologies used for recognition identification of criminals. this paper, we present a standalone application which would allow users create composites sketch suspect without help artists drag drop feature in can automatically match drawn composite police database much faster efficiently deep learning cloud infrastructure. Keywords:...