Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of ischaemic heart (IHD). Statins reduce mortality and morbidity in IHD. It has been hypothesised that statin treatment is associated reduced long-term patients COPD. Using a retrospective cohort design, 854 consecutive (mean age 70.8 yrs; 51.5% female) diagnosis COPD exacerbation were included the study at discharge from Norwegian teaching hospital. Median follow-up was 1.9 yrs, during which 333 died. The...

<h3>Background</h3> Cardiovascular co-morbidities are common in chronic obstructive pulmonary disease (COPD). Retrospective studies on selected patients have indicated that cardiac troponin elevation is frequent during acute exacerbations of COPD (AECOPD), and this associated with poor survival. In the present prospective study prevalence prognostic value elevated T (cTnT) unselected AECOPD been investigated, using a novel high-sensitivity assay (hs-cTnT assay). <h3>Methods results</h3> 99...

Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of cardiovascular disease, exacerbations which increase strain on the heart. The prognostic value elevated circulating levels cardiac Troponins seen during COPD has been investigated. From Akershus hospital database, 897 patients discharged after treatment for exacerbation in period 2000-2003 were identified and followed-up until June 30, 2005. Median observation time was 1.9 yrs. In 396 patients, measurements...

<h3>Objective</h3> To assess the distribution of high-sensitivity cardiac troponin T (hs-cTnT) concentrations in stable chronic obstructive pulmonary disease (COPD), and whether hs-cTnT is associated with function. <h3>Design</h3> Prospectively designed, cross-sectional study. <h3>Setting</h3> Outpatient clinic Norwegian teaching hospital community-based setting. <h3>Participants</h3> Sample 101 COPD patients from hospital9s outpatient 120 individuals derived a random general population...

Abstract. Objective. We investigated the relationship between respiratory symptoms and mortality from all causes in a large Norwegian population. also examined during separate periods of follow‐up. Design. Population‐based, prospective cohort study. Setting subjects. A total 19 998 men women were randomly selected general population Oslo. They received postal questionnaire. The response rate was 88%. Main outcome measures. 11 30 years separately for by multivariate analyses with adjustment...

To investigate if acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is associated with myocardial injury, expressed as elevated high sensitive cardiac troponin T (hs-cTnT), and to identify determinants hs-cTnT in (COPD) patients.In a cross-sectional study, patients hospitalised for AECOPD was compared COPD their stable state.The study conducted at teaching rehabilitation clinic.Consecutive admissions participating units the years 2010-2011 meeting objective, standardised...

Abstract Objectives The objective of this study was to examine whether statin therapy is associated with enhanced endothelium‐dependent vascular function, improved pulmonary function and reduced systemic inflammation in patients chronic obstructive disease ( COPD ). Design setting This randomized, placebo‐controlled, double‐blind, parallel trial including performed at two University hospitals Norway. Subjects, intervention measurements Patients stable n = 99) were assigned randomly receive...

In a survey of 370 aluminium potroom workers in western Norway, bronchial responsiveness, lung function, and respiratory symptoms were studied relation to occupational exposure air contaminants the potroom. Increased prevalences symptoms, work related asthmatic abnormal function found subjects exposed total fluorides above 0.5 mg/m3 when compared with at concentrations less than mg/m3. No significant association between responsiveness fluoride was prevalence independent degree dust exposure....

Cardiac Troponin T (cTnT) elevation during exacerbations of chronic obstructive pulmonary disease (COPD) is associated with increased mortality the first year after hospital discharge. The factors cTnT in COPD are not known. From our hospital's database, all patients admitted exacerbation 2000–03 were identified. 441 had measurement performed. Levels ≥ 0.04 μg/l considered elevated. Clinical and historical data retrieved from patient records, laboratory databases. Odds ratios for calculated...

BACKGROUND--The relation between plasma fluoride levels and bronchial responsiveness was investigated in a longitudinal study aluminium potroom workers who reported work-related asthmatic symptoms. METHODS--From cross-sectional respiratory survey, 26 men symptoms on validated questionnaire were selected for repeated measurements of to methacholine. Regular analyses performed. Exposure total particulates assessed from routine surveillance the workplace. Bronchial expressed as dose-response...

<b>Background:</b> As little is known about the long term relationship between respiratory symptoms and mortality from non-malignant diseases, a study was undertaken to investigate predictive value of symptom load for obstructive lung disease (OLD) pneumonia in Norwegian population. <b>Methods:</b> In 1972, 19 998 persons aged 15–70 years living Oslo were randomly selected survey. The response rate 89%. All followed 30 years. association cough, asthma-like symptoms, two levels dyspnoea on...

The relationship between dust exposure and annual decline in lung function among employees the smelting industry is unknown.The aim of study was to investigate change occupational workers 15 Norwegian smelters.All (n = 2,620) were examined annually for 5 years (11,335 health examinations). At each examination spirometry performed a respiratory questionnaire completed. smelters grouped as follows: (1) ferrosilicon alloys (FeSi) silicon metal (Si-metal); (2) manganese (SiMn), ferromanganese...

Cardiovascular disease (CVD) is a common comorbidity in chronic obstructive pulmonary (COPD). Cardiac troponin (cTn) elevation, indicating myocardial injury, frequent during acute COPD exacerbations and associated with increased mortality. The prognostic value of circulating cTnT among patients the stable state still unknown. purpose present study was to assess association between measured by high sensitive assay (hs-cTnT) all-cause mortality without overt CVD.In prospective cohort we...

The study "Long-term outcome of oxygen supplementation (LTOT

A high-sensitivity cardiac troponin T (hs-cTnT) concentration above the 99th percentile (i.e. 14 ng/L) is common during Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) and associated with increased mortality. The objective study was to identify factors hs-cTnT levels AECOPD. We included 99 patients AECOPD on admission. As 41 had one or more repeat admissions, there were 202 observations in final analysis. recorded clinical biochemical data, medication, spirometry, chest...