- High Altitude and Hypoxia
- Taxation and Legal Issues
- Corporate Taxation and Avoidance
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Cardiovascular Function and Risk Factors
- Neuroscience of respiration and sleep
- Cardiovascular Effects of Exercise
- Sports Performance and Training
- Muscle activation and electromyography studies
- Law and Political Science
- Chronic Obstructive Pulmonary Disease (COPD) Research
- RNA and protein synthesis mechanisms
- Corporate Governance and Law
- Quantum chaos and dynamical systems
- Sports injuries and prevention
- Transcranial Magnetic Stimulation Studies
- Cardiac Imaging and Diagnostics
- Fatty Acid Research and Health
- Cardiovascular and Diving-Related Complications
- Motor Control and Adaptation
- Hemoglobinopathies and Related Disorders
- Quantum and electron transport phenomena
- Space Satellite Systems and Control
- Spacecraft Design and Technology
Université Savoie Mont Blanc
2015-2025
Laboratoire Interuniversitaire de Biologie de la Motricité
2013-2024
Université Claude Bernard Lyon 1
2014-2024
University of Freiburg
2022
Robert Bosch (Germany)
2019-2022
Inserm
2011-2020
Université Grenoble Alpes
2013-2020
Centre Hospitalier Universitaire de Grenoble
2012-2020
Université d'Avignon et des Pays de Vaucluse
2012-2020
John Wiley & Sons (United States)
2018
This study tested the hypothesis that during fatiguing quadriceps exercise, supraspinal fatigue develops late, is associated with both increased corticospinal excitability and inhibition recovers quickly. Eight subjects performed 20 s contractions [15 at 50% maximal voluntary contraction (MVC) followed by 5 MVC] separated a 10 rest period until task failure. Transcranial magnetic stimulation (TMS) electrical femoral nerve (PNS) were delivered ∼ 2 apart MVC, MVC after in relaxed muscle....
Background— The dynamics of systolic and diastolic strains torsional mechanics the left ventricle (LV) their relation to filling never have been evaluated at various exercise intensities. Methods Results— Speckle tracking echocardiography was performed in 20 healthy sedentary subjects rest during a progressive submaximal test 20%, 30%, 40% maximal aerobic power. LV twist increased progressively with intensity (10.5±3.2 15.8±4.5°; P <0.001), whereas longitudinal strain remained unchanged...
Transcranial magnetic stimulation (TMS) is a widely-used investigative technique in motor cortical evaluation. Recently, there has been surge TMS studies evaluating lower-limb fatigue. intensity of 120-130% resting threshold (RMT) and 120% active (AMT) determined using stimulus–response curves during muscular contraction have used these studies. With the expansion fatigue research locomotion, quadriceps femoris increasingly interest. It important to select stimulus appropriate evaluate...
Purpose The well-established central deficit in ultraendurance running races is not understood. use of transcranial magnetic stimulation (TMS) parallel with peripheral nerve provides insight into the source these changes. aims this study were to determine presence and magnitude voluntary activation deficits, especially supraspinal after a mountain trail-running race whether can be explained by simultaneous changes corticospinal excitability intracortical inhibition. Methods Neuromuscular...
Purpose Despite interest in the possibility of females outperforming males ultraendurance sporting events, little is known about sex differences fatigue during prolonged locomotor exercise. This study investigated possible central and peripheral knee extensors plantar flexors resulting from a 110-km ultra-trail-running race. Methods Neuromuscular function was evaluated via transcranial magnetic stimulation (TMS) electrical nerve before after an race 20 experienced trail runners (10 10...
The DLR German Space Operations Center (GSOC) is currently involved in the preparation of two On-Orbit Servicing missions, DEOS and OLEV. Due to the many new challenges within those missions ground segment design requires new concepts. Accordingly, paper presents solutions regarding communication architecture including teleoperation extended contact time. Additionally, we discuss a method vision based navigation which bridges gap between absolute purely geometric navigation. Finally,...
Maximal central motor drive is known to decrease during prolonged exercise although it remains be determined whether a supraspinal deficit exists, and if so, when appears. The purpose of this study was evaluate corticospinal excitability muscle voluntary activation before, after 4-h cycling exercise. Ten healthy subjects performed three 80-min bouts on an ergocycle at 45% their maximal aerobic power. Before immediately each bout, neuromuscular function evaluated in the quadriceps femoris...
Objective The aim of the study is to characterize left ventricular (LV) myocardial mechanics in adults with metabolic syndrome (MetS), and elucidate effects multiple risk‐factors on function using speckle tracking echocardiography (STE); a more sensitive method than conventional for detecting subclinical dysfunction. Design Methods Cross‐sectional analyses 92 (50–70 years) MetS, 50 healthy controls included echocardiography, blood biochemistry, STE‐derived longitudinal, circumferential,...
Ultramarathon runners are exposed to a high number of impact shocks and severe neuromuscular fatigue. Runners may manage mechanical stress muscle fatigue by changing their running kinematics. Our purposes were study (i) the effects 110-km mountain ultramarathon (MUM) on tibial shock acceleration lower limb kinematics, (ii) whether kinematic changes modulated according severity Twenty-three participated in study. Pre- post-MUM, tests performed assess knee extensor (KE) plantar flexor (PF)...
The aim of this study was to analyse the underlying mechanisms left and right ventricular (LV RV) functional alterations during several days in high-altitude hypoxia.Resting evaluations LV RV function mechanics were assessed by Speckle Tracking Echocardiography on 11 subjects at sea level (SLPRE), 3 ± 2 h after helicopter transport high altitude (D0), day (D2), 4 (D4) 6 (D6) 4350 m 5 return (SLPOST). Subjects experienced acute mountain sickness (AMS) first m. systolic function, diastolic...
Slight physiological differences between acute exposure in normobaric hypoxia (NH) and hypobaric (HH) have been reported. Taken together, these suggest different responses to hypoxic a simulated altitude versus terrestrial (HH). For this purpose, the present study, we aimed directly compare time-trial performance after (26 h, 3450 min) by same subjects under three conditions: NH, HH, normoxia (NN). Based on all of preceding studies examining among conditions, hypothesized greater impairment...
ABSTRACT We compared neuromuscular fatigue induced by cycling at a fixed perceived effort in normoxic condition (NOR) and three purported hypoxia modalities: systemic (SyH, FiO 2 = 0.13), blood flow restriction (BFR, 50% arterial occlusion pressure) airflow mask (ARM, calibrated to ~3500 m). Seventeen healthy young participants cycled for 20 min self‐selected power output corresponding hard (15/20, Borg scale) on an innovative cycle ergometer allowing immediate evaluation. Isometric maximum...
Abstract The aim of this study was to assess the effects oxygen availability (normoxia vs. hypoxia), muscle mass and exercise type on pulse saturation, quadriceps oxygenation during repeated sprint exercises. Sixteen healthy participants completed 5 12 s sprints (21 rest). This sprint‐like performed under two environmental conditions (normoxia: FiO 2 = 21%; systemic hypoxia: 13%) for three modalities: unilateral knee extensions (KE) involving right leg extensors (UNI), bilateral KE both legs...