A5089638916- Asthma and respiratory diseases
- Genetic factors in colorectal cancer
- Sarcoma Diagnosis and Treatment
- Immune cells in cancer
- Inhalation and Respiratory Drug Delivery
- Cancer Immunotherapy and Biomarkers
- Gastric Cancer Management and Outcomes
- Nosocomial Infections in ICU
- Metastasis and carcinoma case studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Soft tissue tumor case studies
- RNA modifications and cancer
- Pediatric health and respiratory diseases
- Colorectal and Anal Carcinomas
- Ferroptosis and cancer prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- COVID-19 and healthcare impacts
- Health and Well-being Studies
- Gout, Hyperuricemia, Uric Acid
- Single-cell and spatial transcriptomics
- Lipid metabolism and disorders
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Colorectal Cancer Treatments and Studies
- Inflammatory Biomarkers in Disease Prognosis
Zhongnan Hospital of Wuhan University
2019-2024
Wuhan University
2019-2024
Peking University People's Hospital
2022
Peking University
2022
Hubei Provincial Center for Disease Control and Prevention
2019-2021
Shandong University
2020-2021
Objectives To understand the impact of COVID-19 epidemic on asthma control in children based caregivers’ perspectives and experiences. Design This was a qualitative study deploying face-to-face, semistructured interviews. Thematic analysis carried out to analyse data. Setting Paediatric respiratory clinics three tertiary hospitals. Participants 16 caregivers providing unpaid asthma-related care assistance under 14 years who had been diagnosed with for more than 1 year were not only treated...
Purpose: Caregivers of COPD patients experience various caregiving burden, which is related to their quality life. We aimed explicitly explore whether social support and negative coping styles play the chain mediating roles in relationship between burden caregivers health-related Methods: conducted a multicenter cross-sectional survey four hospitals using convenience sample. Participants who met inclusion criteria completed five relevant scales, including sociodemographic scale. One-way...
Infant antibiotic exposure may be associated with childhood asthma development.To examine and detail this association considering potential confounders.PubMed, EMBASE, Web of Science, the Cochrane Library were searched for publications from January 2011 to March 2021. Eligible studies independently reviewed extract data assess quality. Random effect model was used pool odds ratio (OR) corresponding 95% confidence intervals (CIs).A total 52 included. The infant statistically significant...
Background: Although metabolic syndrome is awell-known risk factor for many non-communicable diseases, its contribution to asthma remains controversial. Objective: The aim of this study was explore the associations and components with incident in Chinese adults. Methods: We conducted an open cohort participants who were asthma-free at baseline (n=42,304) Shandong multi-center health check-up longitudinal from 2004 2015. Participants aged ≥ 20 years had regular physical examination (once...
Several cross-sectional studies have suggested an association between SUA and asthma. However, few investigated this relationship longitudinally. Although is independent risk factor for chronic kidney disease cardiovascular diseases, its contribution to incident asthma remains uncertain.To determine whether a high was adult asthma.By using health care data from the Shandong multicenter check-up, 76,369 participants, aged 20 79 years, were identified who had determination with mean follow-up...
Objective. Adenocarcinoma with mixed subtypes (AM) is a histological classification based on the WHO classification. We aimed to compare prognosis among AM, classic adenocarcinoma (CA), mucinous (MAC), and signet-ring cell carcinoma (SRCC) in early advanced gastric cancer (EGC AGC), respectively. Methods. The Surveillance, Epidemiology, End Results (SEER) database was queried from 2001 2016. Univariate multivariate Cox analyses were performed between AM histologic of CA, SRCC, MAC ECG ACG. A...
Microsatellite stability (MSS) colorectal cancer (CRC) exhibits a low mutation load and poor immunogenicity, contributing to immune escape of tumor cells less benefit from checkpoint blockade (ICB) treatment. The mechanisms underlying immunotherapeutic resistance in MSS CRC remain be elucidated. Here, we identified that nuclear proto-oncogene SET is significantly higher expressed compared microsatellite instability (MSI) facilitates CRC. Mechanistically, represses the expression C-C motif...
Abstract Background: Ventilator-associated pneumonia (VAP) is the second most common nosocomial infection in Intensive care units (ICUs) and associated with significant utilization of health-care resources. However, incidence rates, risk factors mortality rates VAP are controversial. Methods: The Web Science, EMBASE, PubMed Cochrane Library databases through May 2020 were independently searched by two researchers to collect all relevant studies. Data including extracted for meta-analysis....
Abstract Background Based on the WHO classification, adenocarcinoma with mixed subtypes (AM) is a histological classification. We aimed to compare prognosis among AM, classic (CA), mucinous (MAC), and signet-ring cell carcinoma (SRCC) in early advanced gastric cancer (EGC, AGC), respectively. Methods compared clinicopathologic features between AM other histologic of CA, SRCC MAC ECG ACG, A nomogram was established predict cancer-specific survival (CSS) (GC) patients AM. C-index, calibration...
Abstract Purpose Tumor associated macrophages (TAM) influence colorectal cancer (CRC) development, and their clinical significance has been widely established. We intend to depict a full macrophage landscape in order increase our understanding of CRC heterogeneity give improved precision medicine techniques. Methods Use Seurat Cellchat conduct single cell analysis on GSE178341 determine the interaction between cells understand core subsets immune response. SsGSEA was used quantify related...
Aim: There are inter-individual variations in the impact of Beta-2 adrenergic receptor (ADRB2) polymorphisms on salbutamol response asthmatic patients. We performed this meta-analysis to investigate relationship between ADRB2 Arg16Gly and Gln27Glu responsiveness. Methods: Eight cyber databases (PubMed, EMbase, Web Science, The Cochrane Library, CBM, CNKI, WanFang Date VIP) were searched select eligible studies until August 2020. Odds ratio (OR) 95% confidence interval (CI) calculated assess...