- Cell Image Analysis Techniques
- Functional Brain Connectivity Studies
- Biomedical Text Mining and Ontologies
- Brain Tumor Detection and Classification
- Fuzzy Logic and Control Systems
- Cognitive Computing and Networks
- Bioinformatics and Genomic Networks
- Medical Image Segmentation Techniques
- Advanced Neuroimaging Techniques and Applications
- Health, Environment, Cognitive Aging
- Single-cell and spatial transcriptomics
- Scientific Computing and Data Management
- Metabolomics and Mass Spectrometry Studies
- Ethics in Clinical Research
- Advanced MRI Techniques and Applications
- Geological Modeling and Analysis
- Satellite Image Processing and Photogrammetry
- Peripheral Neuropathies and Disorders
- Neural dynamics and brain function
- Research Data Management Practices
- Genetics, Bioinformatics, and Biomedical Research
- Semantic Web and Ontologies
- EEG and Brain-Computer Interfaces
- Artificial Intelligence in Healthcare and Education
- Congenital heart defects research
Applied Minds (United States)
2014-2025
Université Paris Cité
2011
Centre National de la Recherche Scientifique
2011
Délégation Paris 5
2011
University of California, Los Angeles
2007-2008
UCLA Health
2007
The Stimulating Peripheral Activity to Relieve Conditions (SPARC) program is a U.S. National Institutes of Health (NIH) funded effort enhance our understanding the neural circuitry responsible for visceral control. SPARC's mission identify, extract, and compile overall existing knowledge autonomic nervous system (ANS) connectivity between central end organs. A major goal SPARC use this promote development next generation neuromodulation devices bioelectronic medicine diseases. As part...
Digital brain atlases are useful as references, analytical tools, and a data integration framework. As result, they their supporting tools being recognized potentially resources in the movement toward sharing. Several projects connecting infrastructure to these which facilitate sharing, managing, retrieving of different types, scale, even location. With place, we have ability combine, analyze, interpret manner not previously possible, opening door examine issues new exciting ways, leading...
Gene expression signatures in the mammalian brain hold key to understanding neural development and neurological diseases. We have reconstructed two-dimensional images of gene for 20,000 genes a coronal slice mouse at level striatum by using microarrays combination with voxelation resolution 1 mm3. Good reliability microarray results were confirmed multiple replicates, subsequent quantitative RT-PCR voxelation, mass spectrometry publicly available situ hybridization data. Known novel...
Biomedical research entails capture and analysis of massive data volumes new discoveries arise from data-integration mining. This is only possible if can be mapped onto a common framework such as the genome for genomic data. In neuroscience, intrinsically spatial based on number paper atlases. cannot meet today's data-intensive integration challenges. A scalable extensible software infrastructure that standards but open novel resources, required integrating information signal distributions,...
ABSTRACT The Stimulating Peripheral Activity to Relieve Conditions (SPARC) program is a U.S. National Institutes of Health (NIH) funded effort enhance our understanding the neural circuitry responsible for visceral control. SPARC’s mission identify, extract, and compile overall existing knowledge autonomic nervous system (ANS) connectivity between central end organs. A major goal SPARC use this promote development next generation neuromodulation devices bioelectronic medicine diseases. As...
The goal of the INCF Digital Atlasing Program is to provide vision and direction necessary make rapidly growing collection multidimensional data rodent brain (images, gene expression, etc.) widely accessible usable international research community. This Brain Standards Task Force was formed in May 2008 investigate state digital atlasing, formulate standards, guidelines, policy recommendations.Our first objective has been preparation a detailed document that includes specific description an...
Abstract The goal of this workshop was to survey current activities and plans related development mouse rat brain digital atlasing systems. discussed needs for types coordinated action that will ensure rapid progress, compatibility, dissemination with use novel technological approaches. report summarizes the state-of-the-art in field provides recommendations actions.
Event Abstract Back to Development of community standards for brain atlas interoperability Ilya Zaslavsky1*, Richard Baldock2, Jan Bjålie3, Albert Burger4, Mark Ellisman1, Michael Hawrylycz5, Sean Hill6, Stephen Larson1, Maryann Martone1, Lydia Ng5, Raphael Ritz7, Fons Verbeek8 and Jyl Boline9 1 University California San Diego, United States 2 MRC Human Genetics Unit IGMM, 3 Oslo, Institute Basic Medical Sciences, Norway 4 Heriot-Watt University, Kingdom 5 Allen Brain Science, 6 EPFL, Mind...
The International Neuroinformatics Coordinating Facility (INCF) is a standards organization for open and FAIR neuroscience that develops, evaluates, endorses best practices that embrace the principles of Open, FAIR, Citable neuroscience. purpose this document to describe criteria used in INCF's formal procedure evaluating endorsing community practices.
The purpose of this document is to solicit community feedback on the Five Recommendations for FAIR Software, guidelines that aim to apply principles directly software improve research development, which was submitted INCF endorsement as a Best Practice. contains Standards and Practices Committee's review criteria in it evaluated (open, FAIR, testing implementation, governance, adoption use, stability support, comparison similar standards). The committee felt there no need go through formal...
Event Abstract Back to Growing the INCF Digital Atlasing Infrastructure Jyl Boline1*, Richard Baldock2, Rembrandt Bakker3, Albert Burger4, 5, James Gee6, Christian Haselgrove7, Mike Hawrylycz8, Andreas Hess9, G. Allan Johnson10, Piotr Majka11, Lydia L. Ng8, Yuko Okamura-Oho12, Seth W. Rufffins13 and Ilya Zaslavsky14 1 Informed Minds Inc, United States 2 University of Edinburgh, MRC Human Genetics Unit IGMM, Kingdom 3 Radboud University, Netherlands 4 Unit, 5 Heriot-Watt 6 Pennsylvania, 7...
Event Abstract Back to Online registration workflows for atlases of rodent brain and accuracy assessment spatial translation Ilya Zaslavsky1*, Asif Memon2, Stephan Lamont2, David Valentine1, Luis Ibanez3, Gang Song4, Brian Avants4, James Gee4, Yang Liu4 Jyl Boline5 1 San Diego Supercomputer Center, UCSD, United States 2 University California, Diego, 3 Kitware, Inc., 4 Pennsylvania, 5 Informed Minds, Registration diverse sources atlas data standard coordinate spaces, managing transformations...
Event Abstract Back to Registration workflows for the creation of INCF digital atlas hubs Jyl Boline1*, Brian Avants2, Richard Baldock3, Rembrandt Bakker4, Albert Burger5, James Gee2, Christian Haselgrove6, Andreas Hess7, Luis Ibanez8, Stephen Larson9, Piotr Majka10, Yuko Okamura-Oho11, Seth Ruffins12 and Ilya Zaslavsky13 1 Informed Minds, United States 2 University Pennsylvania, 3 MRC Human Genetics Unit IGMM, Kingdom 4 Radboud University, Netherlands 5 Heriot-Watt 6 Massachusetts Medical...
Event Abstract Back to Atlas Registration Services and Workflows within the INCF Digital Atlasing Infrastructure for Rodent Brain Ilya Zaslavsky1*, Stephan Lamont2, Asif Memon2, Luis Ibanez3, James Gee4, Stephen Larson2, David Little2, Valentine1, Richard Baldock5, Mike Hawrylycz6, Janis Breeze7, Raphael Ritz7 Jyl Boline8 1 University of California, San Diego, Diego Supercomputer Center, United States 2 3 Kitware, Inc., 4 Pennsylvania, 5 MRC Human Genetics Unit, Kingdom 6 Allen Institute...
Event Abstract Back to The INCF Digital Atlasing Program, a look back and the future Jyl Boline1*, Mike Hawrylycz2, Ilya Zaslavsky3, Standards Task Force4, Waxholm Space Force4 Infrastructure 1 Informed Minds, United States 2 Allen Institute for Brain Research, 3 University of California, San Diego Supercomputer Center, 4 INCF, Sweden International Neuroinformatics Coordinating Facility (INCF, http://incf.org/) formed Program in fall 2008, response workshop report[1] that recommended create...
Event Abstract Back to INCF Digital Atlasing Infrastructure: Managing Interoperable Atlas Spaces Ilya Zaslavsky1*, Jyl Boline2, Albert Burger3 and Fons Verbeek4 1 University of California, San Diego, United States 2 Informed Minds, 3 MRC, Human Genetics Unit, Kingdom 4 Leiden Inst Advanced Computer Science, Netherlands The goal the task force is define a common framework for exchanging information across neuroscience atlases (Digital Standardization in Rodent Brain, Boline et al). This will...
Workflows are being developed around specific data sharing use cases (Figure 2a). At this time, the focus on 2D brain slice images (some sparsely, others highly sampled) of various modalities. The goal is to create tools, recommendations, and standard operating procedures aid in registration a known atlas space 2b) ability share that through INCF hubs or new (Figures 2c 3). More information can be found at http://atlasing.incf.org/wiki/Workflow.
The integration of neuroscience data is an extremely difficult challenge but presents attractive opportunity to aid progress in brain research. True understanding the can only be achieved through and different scale type. Data at semantic level facilitated by robust ontologies that cross neuroscientific domains. To this domain, International Neuroinformatics Coordinating Facility (INCF) Program on Ontologies Neural Structures (PONS), conjunction with Neuroscience Informatics Framework (NIF),...