Na Guo

ORCID: 0000-0001-5250-7047
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About
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Research Areas
  • Signaling Pathways in Disease
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer
  • Immune Cell Function and Interaction
  • HIV Research and Treatment
  • Building Energy and Comfort Optimization
  • Urban Heat Island Mitigation
  • Thermal Radiation and Cooling Technologies
  • T-cell and B-cell Immunology
  • Health Systems, Economic Evaluations, Quality of Life
  • CAR-T cell therapy research
  • Tuberculosis Research and Epidemiology
  • Immunotherapy and Immune Responses
  • Hepatitis B Virus Studies
  • RNA Research and Splicing
  • Galectins and Cancer Biology
  • Healthcare Systems and Reforms
  • Cancer, Lipids, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • Global Maternal and Child Health
  • Vaccine Coverage and Hesitancy
  • Infectious Diseases and Tuberculosis
  • Cancer-related molecular mechanisms research
  • Cardiac Fibrosis and Remodeling
  • MicroRNA in disease regulation

Central South University
2021-2025

Xi'an Medical University
2015-2025

Hebei Medical University
2025

First Affiliated Hospital of Hebei Medical University
2025

Beijing YouAn Hospital
2019-2024

Capital Medical University
1993-2024

Air Force Medical University
2014-2024

Xijing Hospital
2014-2024

Nanjing Agricultural University
2022-2024

First Hospital of Shijiazhuang
2020-2024

Passive solar heating and radiative cooling have attracted great interest in global energy consumption reduction due to their unique electricity-free advantage. However, static single radiation or would lead overcooling overheating cold hot weather, respectively. To achieve a facile, effective approach for dynamic thermal management, novel structured polyethylene (PE) film was engineered with switchable mode obtained through moisture transfer technique. The 100 μm PE showed excellent...

10.1021/acs.nanolett.3c04996 article EN Nano Letters 2024-01-22

Abstract The unsustainable nature of energy‐intensive and environmentally unfriendly traditional air conditioning systems, compacted with recent climate change effects, show an urgent need for more sustainable efficient thermoregulation solutions. Innovations in passive daytime radiative coolers (PDRCs) selective solar absorbers (SSAs), which utilize natural resources, the “cold” outer space “hot” sun from sky, offer friendly cost‐effective alternative. However, various factors significantly...

10.1002/aenm.202401776 article EN Advanced Energy Materials 2024-06-26

Temozolomide (TMZ) is the first-line chemotherapy drug that has been used to treat glioma for over a decade, but benefits are limited by half of treated patients who acquired resistance. Studies have shown TMZ resistance complex process with multiple factors, which not fully elucidated. Ferroptosis, new type cell death discovered in recent years, reported play an important role tumor The present study reviews relationship between ferroptosis and resistance, highlights Finally, investigators...

10.3389/fonc.2020.00897 article EN cc-by Frontiers in Oncology 2020-06-23

Disturbing mitotic progression via targeted anti-mitotic therapy is an attractive strategy for cancer treatment. Therefore, the exploration and elucidation of molecular targets pathways in mitosis are critical development drugs. Here, we show that cell division cycle 5-like (Cdc5L), a pre-mRNA splicing factor, regulator progression. Depletion Cdc5L causes dramatic arrest, chromosome misalignments sustained activation spindle assembly checkpoint, eventually leading to catastrophe. Moreover,...

10.1038/cddis.2014.117 article EN cc-by-nc-nd Cell Death and Disease 2014-03-27

Ferroptosis is a newly discovered type of cell death decided by iron-dependent lipid peroxidation, but its role in glioblastoma remains unclear. Ibuprofen, nonsteroidal anti-inflammatory drug (NSAID), has been associated with antitumorigenic effects many cancers. In this study, we first found that ibuprofen inhibited the viabilities cells vitro and vivo, accompanied abnormal increase intracellular peroxidation. Further study showed growth inhibition caused could be rescued ferroptosis...

10.1097/cad.0000000000000825 article EN Anti-Cancer Drugs 2019-09-05

Traditional radiative cooling leads to overcooling in the winter season and increases total energy consumption of buildings. And, super white color limits its practical applications. In this work, a bilayer coating consisting polydimethylsiloxane (PDMS)@thermochromic dye film as top layer polytetrafluoroethylene bottom is designed achieve self‐adaptive colored by tuning visible spectra. The mass ratio PDMS black thermochromic 1: 0.04 balance solar heating performances although thermal...

10.1002/solr.202300512 article EN Solar RRL 2023-09-13

Cooling environments are a pervasive need in our society, with conventional air conditioners being the most popular approach. However, rely heavily on electricity and Freon, chemical that depletes ozone contributes to greenhouse gas effects. To address this issue, passive daytime radiative coolers (PDRCs) have been proposed achieve cooling by simultaneously reflecting sunlight allowing internal heat escape without electricity. Despite their potential, high-performance PDRCs composed of thick...

10.1021/acs.langmuir.4c02567 article EN Langmuir 2024-09-09

Pathological cardiac hypertrophy is associated with dysfunction and a key risk factor for heart failure even sudden death. This study investigates the function of Mycn in explores interacting molecules.

10.1186/s12872-024-03748-8 article EN cc-by BMC Cardiovascular Disorders 2024-01-31

China's health system has shown remarkable progress in provision and outcomes recent decades, however inequality care utilization persists poses a serious social problem. While government pro-poor policies addressed affordability as the major obstacle to equality access, this policy direction deserves further examination. Our study examines issue of inequalities China, analyzing both regional individual socioeconomic factors associated with inequality, provides evidence improve governmental...

10.1186/s12939-017-0706-8 article EN cc-by International Journal for Equity in Health 2017-12-01

Seedling drought stress is one of the most important constraints affecting soybean yield and quality. To unravel molecular mechanisms under tolerance, we conducted comprehensive comparative transcriptome analyses drought-tolerant genotype Jindou 21 (JD) drought-sensitive Tianlong No.1 (N1) seedlings that had been exposed to treatment. A total 6038 4112 differentially expressed genes (DEGs) were identified in JD N1, respectively. Subsequent KEGG pathway showed numerous DEGs are predominately...

10.3390/ijms23052893 article EN International Journal of Molecular Sciences 2022-03-07

Acyl-CoA synthetase long-chain family member 4 (ACSL4) has been linked to the ferroptosis process and is implicated in pathogenesis of tumors. Nevertheless, neither expression levels ACSL4 nor its prognostic significance clear cell renal carcinoma (ccRCC) completely understood at this time.Predictions mRNA ccRCC link prognosis were made based on data from Oncomine The Cancer Genome Atlas (TCGA) databases. Through use real-time polymerase chain reaction (PCR), we ascertained human RCC...

10.21037/tcr-21-2157 article EN Translational Cancer Research 2022-08-01

With the improvement of living standards, energy consumption for heating and cooling is increasing. Traditional heaters or coolers (air conditioners etc.) consume lots only transfer heat to different places on Earth, which increases ambient temperature load power. Solar sky radiative by sun (∼ 5800 K) outer space 3 have attracted attention recently due their saving sustainability, also shown great potential in thermal management applications cooling. While static solar mode would lead...

10.1016/j.nxener.2023.100072 article EN cc-by-nc-nd Next Energy 2023-10-17

As the initial stage for children to receive knowledge systematically, pre-school education not only affects quality of family life and happiness index, but also is an important indicator measure level urban development. Kindergarten main facility carrier education. This study uses population census data kindergarten degree other multi-source data, based on street scale, presents a systematic analysis spatial distribution kindergarten, relationship between supply demand educational...

10.54097/sds0vc94 article EN Journal of Education and Educational Research 2025-01-28

Passive solar heating and radiative cooling attracted lots of attention in global energy consumption reduction due to their unique electricity-free advantage. However, static single radiation or would lead over-cooling over-heating cold hot weather, respectively. How achieve effective self-adaptive thermoregulation is critical for dynamic thermal management. Hence, this work, a strategy was designed by coupling latent heat storage release with reversible cooling. A commercial memory alloy...

10.1063/5.0262028 article EN Applied Physics Letters 2025-03-01

Abstract Objectives Central precocious puberty (CPP) is one of the common endocrine diseases in pediatrics. However, molecular mechanisms regulating development CPP have remained unclear. The purpose this study was to discover key pathways and hub genes related CPP. Methods We analyzed two public datasets (GSE7142 GSE8310) identify differentially expressed progression Then, we screened out overlapping differential from these performed a series bioinformatics analyses explore promising...

10.1515/jpem-2024-0617 article EN Journal of Pediatric Endocrinology and Metabolism 2025-03-20
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