A5048777235- RNA modifications and cancer
- Cancer Mechanisms and Therapy
- Geochemistry and Geologic Mapping
- Immune Cell Function and Interaction
- MicroRNA in disease regulation
- Natural product bioactivities and synthesis
- Geological and Geochemical Analysis
- Hydraulic Fracturing and Reservoir Analysis
- Pharmacological Effects of Natural Compounds
- Peptidase Inhibition and Analysis
- Rheumatoid Arthritis Research and Therapies
- Signaling Pathways in Disease
- Cancer-related molecular mechanisms research
- Rock Mechanics and Modeling
- Synthesis and Biological Activity
- Biological Activity of Diterpenoids and Biflavonoids
- Cancer, Stress, Anesthesia, and Immune Response
- Cell death mechanisms and regulation
- Bioactive Compounds and Antitumor Agents
- Synthesis and biological activity
- Mineralogy and Gemology Studies
- Eosinophilic Esophagitis
- Ferroptosis and cancer prognosis
- Molten salt chemistry and electrochemical processes
- Phytochemical compounds biological activities
Hunan Normal University
2022-2025
Guangdong Ocean University
2023-2024
General Research Institute for Nonferrous Metals (China)
2024
Xi'an Medical University
2014-2024
Grinm Advanced Materials (China)
2024
Thermo Fisher Scientific (China)
2023
China Coal Technology and Engineering Group Corp (China)
2023
Xiamen University
2022
China Geological Survey
2021
Software Engineering Institute of Guangzhou
2021
Temozolomide (TMZ) is the first-line chemotherapy drug that has been used to treat glioma for over a decade, but benefits are limited by half of treated patients who acquired resistance. Studies have shown TMZ resistance complex process with multiple factors, which not fully elucidated. Ferroptosis, new type cell death discovered in recent years, reported play an important role tumor The present study reviews relationship between ferroptosis and resistance, highlights Finally, investigators...
Long non‑coding RNA (lncRNA) urothelial carcinoma‑associated 1 (UCA1) has been used in tumor development and progression many types of cancer. However, the function mechanism underlying action UCA1 papillary thyroid cancer (PTC) remains unclear. Therefore, these topics were investigated present study by vitro vivo experiments. It was demonstrated that expression level more significantly upregulated PTC cell lines tissues when compared with immortal human follicular line adjacent normal...
Glioblastoma(GBM) is one of the most common and aggressive malignant primary tumors central nervous system mitochondria have been proposed to participate in GBM tumorigenesis. Previous studies identified a potential role Disrupted Schizophrenia 1 (DISC1), multi-compartmentalized protein, mitochondria. But whether DISC1 could regulate tumorigenesis via still unknown. We determined expression level by both bioinformatics analysis tissue analysis, found that was highly expressed GBM. Knocking...
Rapamycin is clinically used as an immunosuppressant. Increasing evidence suggests that rapamycin has important inhibitory role in the development and progression of different types cancer it a promising candidate for chemotherapy. Berberine isoquinoline alkaloid isolated from medicinal plant species, which been traditional Chinese medicine with no significant side effects. Recent research demonstrated berberine anticancer activity against various cancer, mediated through suppression...
Shikonin, a traditional Chinese medicine, has been identified as being capable of inducing apoptosis in various tumors, including glioma, and is thus considered to be promising therapeutic agent for tumor therapy. However, little known about the molecular mechanism shikonin glioma. The present study investigated influence on proliferation glioma cells U251 U87MG explored potential mechanisms. It was that able induce human time‑ dose‑dependent manner, decreased expression level cluster...
According to the characteristics of coal-rock dynamic disasters and hydraulic slotting, mechanism load barrier static pressure relief in slotting is proposed. The stress distribution a coal mining face slotted area section pillar analyzed by numerical simulation. results show that slot formed can effectively alleviate concentration transfer high-stress deeper seam. When blocking propagation path seam, wave intensity transmitted into greatly reduced, so risk disaster reduced. A field...
In this contribution, the Sr and Nd isotopic compositions of four Chinese National Standards are investigated to verify whether they meet requirements international reference materials. Powdered samples were digested using conventional HF HNO3 acid dissolution protocols, chemical purification was performed Spec, AG 50W-X12 LN resin. All measurements carried out on a Thermal Ionization Mass Spectrometry (TIMS) at Laoshan Laboratory. We report standards as follows: GSR-1 (granite): 87Sr/86Sr =...
The starch synthase (SS) plays important roles in regulating plant growth and development responding to adversity stresses. Although the SS family has been studied many crops, it not fully identified sweet potato its two related species. In present study, eight SSs were from Ipomoea batatas (I. batata), trifida trifida), trlioba trlioba), respectively. According phylogenetic relationships, they divided into five subgroups. protein properties, chromosomal location, gene structure,...
The rise and prosperity of cross-border e-commerce has brought new development opportunities great challenges to Chinese enterprises. By discussing the concepts contents enterprise competitiveness, this paper analyzes influencing factors competitiveness means questionnaires interviews with management relevant enterprises, data were obtained. In dimensional analysis discussed. results show that flat organizational structure is conducive enhance fund human resource play a more obvious role;...
With the development of higher education informatization, traditional teaching mode can not adapt to learning needs students in new era. Online and offline hybrid has attracted more attention from state academic circles. Taking 644 papers CNKI as samples, this paper uses CiteSpace software do visual analysis literature, aiming clearly understand hot spots trend online research China, provide reference inspiration for future research. The results show that: China is a stage active...