A5004517928- Renal Transplantation Outcomes and Treatments
- Pharmaceutical Practices and Patient Outcomes
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac electrophysiology and arrhythmias
- Heparin-Induced Thrombocytopenia and Thrombosis
- Patient Safety and Medication Errors
- Atrial Fibrillation Management and Outcomes
- Ocular Diseases and Behçet’s Syndrome
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Peroxisome Proliferator-Activated Receptors
- Antifungal resistance and susceptibility
- Ion channel regulation and function
- Drug Transport and Resistance Mechanisms
- Oral and gingival health research
- Acute Myocardial Infarction Research
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacogenetics and Drug Metabolism
- Cytomegalovirus and herpesvirus research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Herpesvirus Infections and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Cholesterol and Lipid Metabolism
- Adrenal Hormones and Disorders
Monmouth Medical Center
2009-2021
St. Barnabas Hospital
2015
Saint Barnabas Medical Center
2000-2013
Rutgers, The State University of New Jersey
2000-2005
Rütgers (Germany)
2001
Rutgers Sexual and Reproductive Health and Rights
2001
Although multiple studies of demographic variables have been associated with allograft thrombosis, these results are not routinely reproducible. Are ESRD patients hypercoagulable states (HCS) (antithrombin III deficiency, protein S or C activated resistance, and anticardiolipin antibodies) at predictably greater risk for thrombosis?Between 1996 1999, all renal transplant candidates were screened hypercoagulability factors [HRF] (multiple arteriovenous access thromboses, prior deep vein...
Purpose: The frequency, onset, mechanisms, and causes of dyslipidemia after renal transplantation are reviewed in the context adverse impact lipid alterations, recent guidelines, available treatment options. Summary: At least 60% adult transplant recipients develop dyslipidemia, which occurs within one month initiation immunosuppressive therapy continues indefinitely unless treated. Cyclosporine, sirolimus, prednisone mainly implicated, profile differs between individual agents. In...
Background. The optimal regimen for prophylaxis of cytomegalovirus (CMV) disease after kidney and/or pancreas transplantation remains unclear. We compared the effectiveness three months oral ganciclovir (3 g/day) versus low-dose valganciclovir (450 mg/day) CMV prophylaxis. Methods. performed a retrospective cohort study patients at our center who received transplants between January 2000 and April 2003. used Cox proportional hazards model to examine relationship baseline covariates,...
BACKGROUND Heparin can reduce the risk of renal artery/vein thrombosis in transplant patients with hypercoagulable states (HCS), but is associated a high bleeding risk. Little known about factors for this or optimal anticoagulation target. OBJECTIVE To determine and partial thromboplastin time (PTT) ratio. METHODS We retrospectively reviewed medical records consecutive adult recipients administered heparin perioperative prevention (1998–2002). RESULTS Twenty-eight (3.86%) 725 received to...
To describe a case of levofloxacin-induced partial Achilles tendon rupture; this occurred in the presence known risk factors and acute renal failure.A 79-year-old white man received levofloxacin for presumed pneumonia, developed failure setting dehydration, began having ankle pain on 12th day admission. Levofloxacin was discontinued, magnetic resonance imaging revealed 6-cm tear degenerative changes.The Naranjo probability scale indicates possible association between rupture because event...
The use of adjunct, non-opioid agents is integral for pain control following total hip and knee arthroplasty. Literature comparing safety profiles intravenous acetaminophen versus opioids lacking.To determine whether there a difference in frequency type adverse effects between acetaminophen-treated non-intravenous patients. Primary endpoints included any effect noted the electronic medical record post-surgically. Secondary changes laboratory values, vital signs, scores.This retrospective,...
Calcineurin inhibitors (CNI) and azole antifungal agents have been reported to interact in a disparate manner. The dose route the level of involvement liver intestines implicated, although data are limited. A significant interaction may result CNI toxicity, withdrawal subtherapeutic concentrations. Fluconazole, available both intravenous oral formulations, is commonly used transplant recipients ideal for determining presence effect on We retrospectively investigated CNIs with fluconazole,...
Clinical monitoring of organ-transplant recipients suggests that administration cyclosporine (CsA) may increase the risk atherosclerosis when compared with general population. The purpose this work is to demonstrate utility in vitro Tamm-Horsfall protein (THP)-1 human monocyte cell culture model for determining drug-related atherosclerotic potential macrophages. effect CsA on mRNA expression macrophage scavenger receptor genes including CD36, CD68, (SR)-A, SR-BII, and lectin-like oxidized...
We assessed the rates of influenza vaccine acceptance and reasons for or refusal among medical residents in different disciplines during 2004-2005 season. Rates varied disciplines; emergency department had lowest rate (24%). The perception a low risk contracting was most common reason reported refusal.
PRINCIPLES: We aimed to evaluate the efficacy of, and treatment satisfaction with, insulin glargine administered with SoloSTAR® or ClikSTAR® pens in patients type 2 diabetes mellitus managed by primary care physicians Switzerland. METHODS: A total of 327 inadequately controlled were enrolled 72 this prospective observational study, which a 6-month course therapy measured as development glycaemic control (glycosylated haemoglobin [HbA1c] fasting plasma glucose [FPG]) weight change. also...
Study Objective . To determine prescribing patterns and clinical outcomes of enoxaparin for anticoagulation atrial fibrillation. Design Retrospective analysis. Setting A 650‐bed, tertiary care, community teaching hospital. Subjects Two hundred thirteen patients who received thromboprophylaxis during an episode Intervention Data collection on demographics, antithrombotic usage, thrombotic bleeding episodes from January‐June 2001. Measurements Main Results Patients were characterized as having...
Background. Data indicate that tacrolimus and cyclosporine A (CsA) differentially affect the risk of atherosclerosis. The results our recent in vitro studies clinically relevant CsA concentrations demonstrated modulation macrophage scavenger receptors (MSRs) involved atherogenesis. This work evaluated effects on expression MSR genes CD36 CD68, SR-A SR-BII, lectin-like oxidized low-density lipoprotein receptor-1, nuclear hormone peroxisome proliferator-activated receptor (PPAR)γ...
BACKGROUND: Bleeding is a common and costly complication of percutaneous coronary intervention (PCI). Little known about the risk factors for bleeding complications. Objective: To report our PCI-related observations from single institution use information to establish short-term complications, with special focus on examining importance renal function. METHODS: A retrospective record review was conducted admission 300 patients grouped according antithrombotic regimen: unfractionated heparin...