A5079187407- Grief, Bereavement, and Mental Health
- Pharmacovigilance and Adverse Drug Reactions
- Complementary and Alternative Medicine Studies
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Maternal Mental Health During Pregnancy and Postpartum
- Maternal and Perinatal Health Interventions
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 Impact on Reproduction
- Cannabis and Cannabinoid Research
- Vaccine Coverage and Hesitancy
- Global Maternal and Child Health
- Blood Pressure and Hypertension Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Inflammatory mediators and NSAID effects
- Palliative Care and End-of-Life Issues
- Migration, Health and Trauma
- SARS-CoV-2 and COVID-19 Research
- Eating Disorders and Behaviors
- Breastfeeding Practices and Influences
- Pharmacogenetics and Drug Metabolism
- Atrial Fibrillation Management and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Influenza Virus Research Studies
- Pregnancy and preeclampsia studies
University of Florence
2016-2025
Agenzia Regionale di Sanità della Toscana
2009-2024
Tescan (Czechia)
2008-2021
Regione Toscana
2012-2021
Florence (Netherlands)
2008-2020
Nuovo Ospedale di Prato
2018-2019
Sands
2016-2018
Health Alliance International
2016
Azienda Ospedaliero-Universitaria Careggi
2002-2013
University of Verona
2011
In March 2020, COVID-19 was declared to be a pandemic. While data suggests that is not associated with significant adverse health outcomes for pregnant women and newborns, the psychological impact on likely high.The aim explore of pandemic Italian women, especially regarding concerns birth expectations.A cross-sectional online survey in Italy conducted. Responses were analysed all segregated into two groups depending previous experience pregnancy loss. Analysis open text responses examined...
We evaluated the role of COX-2 pathway in 35 head and neck cancers (HNCs) by analyzing expression prostaglandin E2 (PGE2) production relation to tumor angiogenesis lymph node metastasis. activity was also correlated vascular endothelial growth factor (VEGF) mRNA protein expression. higher samples than normal mucosa. PGE2 levels were front zone comparison with core mucosa (P<.0001). Specimens from patients metastasis exhibited (P=.0074), (P=.0011) microvessel density (P<.0001) specimens...
Eating disorders are frequent among elite performers of certain sports or physical activities; however, little is known about non-professional performers.113 female non-elite ballet dancers, 54 gymnasium users, 44 male non-competitive body builders, 105 controls and 30 were evaluated using the Body Uneasiness Test, State-Trait Anxiety Inventory, Beck Depression Disorder Examination 12th edition (EDE-12).Non-elite dancers reported highest prevalence eating (anorexia nervosa 1.8%; bulimia...
To obtain further information on time course and mechanisms of cell death after poly(ADP-ribose) polymerase-1 (PARP-1) hyperactivation, we used HeLa cells exposed for 1 h to the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. This treatment activated PARP-1 caused a rapid drop cellular NAD(H) ATP contents, culminating 8-12 later in death. antagonists fully prevented nucleotide depletion Interestingly, early 60 min challenge with N-methyl-N'-nitro-N-nitrosoguanidine, mitochondrial...
Abstract Cyclooxygenase (COX)-2 and 5-lipoxygenase (5-LOX) are key enzymes involved in arachidonic acid metabolism. Their products, prostaglandins leukotrienes, colorectal tumor development. We aimed at evaluating whether combined blocking of the COX-2 5-LOX pathways might have additive antitumor effects cancer. The expression/activity were assessed 24 human cancer specimens. inhibitor celecoxib MK886 on prostaglandin E2 cysteinyl leukotriene production, cell proliferation, apoptosis,...
Drug-induced liver injury is one of the most serious adverse drug reactions and frequent reason for restriction indications or withdrawal drugs. Some nonsteroidal anti-inflammatory drugs (NSAIDs) were withdrawn from market because hepatotoxicity. We estimated risk acute associated with use nimesulide other NSAIDs, a prevalence greater than equal to 5%.This multicentre case-control study carried out in nine Italian hospitals October 2010 January 2014. Cases adults, diagnosis injury. Controls...
Italy was the first COVID-19 pandemic epicenter among European countries and established a period of full "lockdown", consisting travel bans, mandatory staying at home, temporary closure nonessential businesses. Similar measures are known risk factors for psychological disturbances in general population; still, little is about their impact on pregnant women's mental health during pandemic. The cross-sectional, web-based, national survey "COVID-19 related Anxiety StreSs prEgnancy, poSt-partum...
To explore pregnant women's use, attitudes, knowledge and beliefs of complementary alternative drugs (CADs) defined as products manufactured from herbs or with a natural origin. A preliminary survey was conducted among 172 women in their third trimester pregnancy, consecutively recruited two obstetrical settings; 15 were randomly selected to compute test-to-retest analysis. Response rate 87.2%. Test-to-retest analysis showed questionnaire's reproducibility exceeding K-value 0.7 for all...
Fennel (Foeniculum vulgare Mill.) mature fruit (commonly known as seeds) and essential oil of fennel are widely used flavoring agents in food products such liqueurs, bread, cheese, an ingredient cosmetics pharmaceutical products. Moreover infusions the classical decoction for nursing babies to prevent flatulence colic spasm. Traditionally Europe Mediterranean areas is antispasmodic, diuretic, anti-inflammatory, analgesic, secretomotor, secretolytic, galactagogue, eye lotion, antioxidant...
To assess the frequency of additional care, and parents' perceptions quality, respectful in pregnancies subsequent to stillbirth.Multi-language web-based survey.International.A total 2716 parents, from 40 high- middle-income countries.Data were obtained a broader survey experiences following stillbirth. Data analysed using descriptive statistics stratified by geographic region. Subgroup analyses explored variation care gestational age at index stillbirth.Frequency care.The majority (66%)...