A5084095459- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
- AI in cancer detection
- Hippo pathway signaling and YAP/TAZ
- Hedgehog Signaling Pathway Studies
- Single-cell and spatial transcriptomics
- Glioma Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Immune cells in cancer
University Hospital Heidelberg
2022-2023
Heidelberg University
2022-2023
Hopp Children's Cancer Center Heidelberg
2021
Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity terms of molecularly distinct entities, cellular origins and genetic drivers than anticipated from histological assessment. DNA methylation has emerged as useful tool for robust tumor classification, providing new insights into these heterogeneous classes. This is particularly true rare CNS with broad morphological spectrum, which are not possible...
<p>Diagnostic performance obtained by four independent repetitions of creating a SVM classifier on the basis clinical parameters recorded for 302 IPMN patients.</p>
<p>Diagnostic performance of serum protein panels.</p>
<p>Diagnostic performance of serum miRNA panels.</p>
<p>Diagnostic performance obtained by four independent repetitions of creating a SVM classifier on the basis clinical parameters recorded for 302 IPMN patients.</p>
<p>Diagnostic performance of serum miRNA panels.</p>
<div>AbstractPurpose:<p>Intraductal papillary mucinous neoplasm (IPMN) is a precursor of pancreatic ductal adenocarcinoma. Low-grade dysplasia has relatively good prognosis, whereas high-grade and IPMN invasive carcinoma require surgical intervention. However, diagnostic distinction difficult. We aimed to identify biomarkers in peripheral blood for accurate discrimination.</p>Experimental Design:<p>Sera were obtained from 302 patients with IPMNs 88 healthy donors. For...
<div>AbstractPurpose:<p>Intraductal papillary mucinous neoplasm (IPMN) is a precursor of pancreatic ductal adenocarcinoma. Low-grade dysplasia has relatively good prognosis, whereas high-grade and IPMN invasive carcinoma require surgical intervention. However, diagnostic distinction difficult. We aimed to identify biomarkers in peripheral blood for accurate discrimination.</p>Experimental Design:<p>Sera were obtained from 302 patients with IPMNs 88 healthy donors. For...
<p>Diagnostic performance of serum protein panels.</p>