A5110989009- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Cancer Cells and Metastasis
- Wnt/β-catenin signaling in development and cancer
- Epigenetics and DNA Methylation
- Salivary Gland Tumors Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Myasthenia Gravis and Thymoma
- Tumors and Oncological Cases
- Surgical site infection prevention
- Cancer Mechanisms and Therapy
- Cancer-related gene regulation
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
Background: Circulating tumor cells (CTCs) play an important role in hematogenous metastasis of malignant tumors. Small cell lung cancer (SCLC) is the most aggressive form with highest number detected CTCs. Objective: To evaluate presence and CTCs as immunosuppression factor SCLC. Materials methods : In 30 patients stage III-IV SCLC, were using CellSearch system (Veridex LLC, Belgium) before treatment. The participants divided into groups based on Flow cytometry was used to assess T- natural...
Adenoid cystic carcinoma of the lung is a relatively rare malignant tumor, accounting for 0.04–0.2 % all primary tumors respiratory system. This can occur at any age, but it more common in 40–60 age group and usually women. The main treatment method adenoid surgical. Since this histological form are often centrally located, options bronchoplastic operations considered. In childhood, extremely rare, performing lobectomies children associated with several difficulties, such as smaller diameter...
Purpose of the study. To conduct a comparative analysis E-cadherin expression in inoperable patients with non-small cell lung cancer (NSCLC) cells and different survival rates. Materials methods. The study included 96 NSCLC: 84 (87.5 %) men 12 (12.5 women, whose average age was 62.4 ± 0.68 years. Squamous carcinoma (SCC) diagnosed 78 (81.25 patients, adenocarcinoma (AC) tumor differentiation grade G2-G3 18 (18.75 %). were treated monitored at National Medical Research Centre for Oncology....
Despite significant advances in the treatment of malignant neoplasms, issue therapy resistance mediated by cancer stem cells (CSCs) necessitates development new strategies. Studying role CSCs and immune microenvironment pathogenesis cancer, particularly non-small cell lung (NSCLC), is a pressing modern oncology. This paper based on an extensive analysis recent research aims to study mechanisms underlying NSCLC. The origin CSCs, their markers, main signaling pathways involved regulating...
Thymomas and carcinomas of the thymus gland, also known as epithelial tumors (TT) are rare malignant neoplasms, but most common solid anterior mediastinum. The incidence does not exceed 1.3–1.7 per million inhabitants year. In Europe, about 1,500 new cases registered annually, average age patients is around 40–50 years. Originating from component thymus, primary lymphoid organ, they accompanied by a high risk developing autoimmune disorders due to their unique biology. Indeed, up 30 % TETS...
Lung resection is the main diagnostic and therapeutic surgical intervention in terms of lung cancer management. Air leak through pleural drains often occurs after resections due to damage pulmonary parenchyma. Therefore, proper drainage cavity very important for successful outcome operation. The installation a single anatomical resection, refusal use vacuum aspiration earliest possible removal contribute rapid activation patients postoperative period. Prolonged air leakage (PAL) on average,...
The purpose of the study. To analyze levels sex hormones and cortisol in lung tissues patients with cancer previous COVID‑19 different severity. Materials methods. material for study included samples obtained after open biopsy at radical surgery from 60 morphologically verified stage I–IIIA non‑small cell (NSCLC) (сT 1–3 N Х M 0 ). mean age was 59.11 ± 2.9 years. All had negative results SARS‑CoV‑2 nasopharyngeal swab PCR testing hospitalization. Based on anamnestic data collected using a...