Both type 2 diabetes and hypothyroidism are highly prevalent disorders in the community. The existing data regarding prevalence of patients with comes mostly from small studies. There only two studies a sample size more than 1000 diabetic patients, none which have been done South Asians. present study evaluated for presence clinical factors associated it. demographic, anthropometric, clinical, biochemical parameters consecutively enrolled were systematically collected analyzed. A total 1152...

An accelerated atherosclerotic process is a significant contributor to the development of vascular complications in diabetes. Endothelial dysfunction and heightened platelet hyperactivity diabetes exacerbate vasoconstriction thrombus formation, thereby accelerating process. The hyperreactivity associated with prothrombotic state characterised by alterations morphology function. Platelet indices, such as volume, distribution width, platelet-large cell ratio plateletcrit, reflect these...

Introduction: Diabetes awareness and knowledge is a preliminary step towards controlling limiting the diabetes burden globally. There pressing need for creating validated tests of different targeted groups.Objective: To create validate (DAK) test medical nursing students. Methods: We created 47 item 50 marks English DAK with questions from domains like basics diabetes: types, symptoms, pathophysiology diagnosis diabetes, its risk factors, basic about treatment including diet activity...

complaint. Asthenia is a subjective, static feeling of weakness, not necessarily related to effort. We propose simple algorithm which can help primary care physicians in evaluation and counselling persons presenting with asthenia. (Table 1). This equally important acute symptoms chronic lifestyle diseases. Keywords: Anabolic, asthenia, catabolism, fatigue, person centred

The Indian population can be divided broadly into Dravidians and the Aryans. In this report, we have attempted to analyze HLA genetic profile of 400 native North Hindus Aryan descent. gene frequencies a majority class I II antigens show similarity Caucasoid population. An interesting finding was complete lack antigen B14 while B16 B41 occurred with least frequency. Haplotype A10, B8 significant positive linkage disequilibrium as well showing highest incidence is characteristic Indians.

Context: There are limited data about the effect of metformin use on serum Vitamin B12 levels in type 2 diabetes patients from India. Aims: We studied with mellitus who were receiving and compared them to those never treated metformin. Subjects Methods: A total 183 ("metformin" group 121, "no metformin" 63) endocrinology clinic a tertiary care center North India studied. Serum measured all patients. Diabetic neuropathy symptom score (DNS) diabetic examination (DNE) used assess peripheral...

Diabetes mellitus is a metabolic disorder that often predisposes to cardiovascular diseases (CVD). CVD an important cause of morbidity and mortality in diabetes. The typical diabetic dyslipidaemia characterized by low HDL cholesterol, high triglycerides with mildly increased or even normal LDL. This attenuated rise LDL due the more atherogenic small dense particles. Genetic factors, obesity, lack physical activity, alcohol abuse, poorly controlled glucose levels are some common risk factors...

Sir, We read with great interest the article by Kumar et al.,[1] regarding endocrine dysfunction among patients coronavirus disease-19 (COVID-19). While there have been reports of pituitary involvement in COVID-19 form apoplexy on background underlying adenoma, we recently came across a case hypophysitis after infection.[2] A 27-year-old male patient presented malaise, anorexia, and vomiting associated early morning headaches since past 4 weeks. He did not fever, diplopia, pain abdomen or...

Meta-analysis studying the role of verapamil in improving C-peptide people with recent-onset type-1 diabetes (T1DM) has not been conducted to date. We undertook this meta-analysis address knowledge gap. Electronic databases were systematically reviewed for RCTs having individuals T1DM receiving treatment arm and placebo control over standard care. The primary outcome was evaluate changes area under curve (AUC) at a one-year follow-up. Secondary outcomes assess alterations AUC, glycated...

Introduction: The prediction of gestational diabetes mellitus (GDM) by serum adiponectin levels has shown promise in Western literature. This study looks at the first trimester as a predictor Indian women. Material and Methods: A total 450 pregnant women were screened 11-- 13 weeks gestation samples stored. All underwent an oral glucose tolerance test to diagnose GDM International Association Diabetes Pregnancy Group criteria 24-- 28 gestation. Amongst these, 45 who had developed compared...

Abstract Primary hyperparathyroidism, typically a disease of the middle aged and old, is less commonly seen in children. In children has bimodal age distribution with calcium sensing receptor mutation presenting infancy as hypercalcemic crises parathyroid adenoma or hyperplasia later childhood bone disease. The adenomas are often familial multiglandular manifest severe unlike adults. We report series four male patients juvenile primary three whom presented masquerading rickets-osteomalacia....

Since our previous study in 2006, several new modalities for localization of cause endogenous hyperinsulinemic hypoglycaemia such as multiphasic computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound (EUS), intraoperative ultrasound, and intra-arterial calcium infusion with arterial stimulation venous sampling (ASVS) have become available. Therefore, to evaluate the relative usefulness various guide future management terms diagnosis patient care, we analyzed...

Background: Serum 25-hydroxyvitamin D (25(OH)D) assays have become readily available in India over the past decade. A large number of cross-sectional studies been performed on vitamin status and prevalence deficiency (VDD) India. However, seasonal long-term trends serum 25(OH)D levels reported less frequently. Aim: To determine year-wise variation at a tertiary care hospital north Materials Methods: Using records, data 25(OH) its endocrinology laboratory between 2008 2016 were obtained. For...

Acute pancreatitis complicating fulminant viral hepatitis has been well recognized; however, acute occurring in nonfulminant is very rare. The case presented describes moderate a young male, manifesting during the course of E infection. diagnosis was confirmed by serology and reverse transcriptase polymerase chain reaction (RT-PCR) to demonstrate Hepatitis virus (HEV) RNA both stool serum. Patients with presenting severe abdominal pain should have suspected appropriate investigations...

ABSTRACT Purpose: The purpose of this study was to assess the impact oral health status (OHS) and sociodemographic indicators on health-related quality life (OHRQoL) among children with type 1 diabetes mellitus (T1DM) aged 11–14 years compare it age-matched nondiabetic children. Materials Methods: This cross-sectional included 80 between 11 14 T1DM OHRQoL measured using a validated structured Hindi version child perception questionnaire (CPQ 11-14 ) questionnaire. clinical OHS assessed...

We present here a case of young male with complaints fever and swelling in the neck for eight months. History progressive weakness associated weight loss was present. Physical examination revealed pallor, multiple enlarged cervical lymph nodes hepatosplenomegaly. Investigations showed pancytopenia, hyperglobinemia Leishman-Donovan bodies on bone marrow aspiration. Serological test confirmed diagnosis visceral leishmaniasis. However, node aspiration biopsy were suggestive Mixed cellularity...

There is equipoise regarding the status of bone mineral density (BMD) in patients with congenital adrenal hyperplasia (CAH), where need to be on long-term low-dose steroids.We aimed evaluate BMD at hip, spine and forearm women CAH compare it healthy young adult same age range.Fifteen ranging from 18 40 years (mean ± standard deviation = 27.5 6.2 years) underwent dual-energy X-ray absorptiometry along laboratory evaluation. lumbar spine, T-scores were measured. Serum total calcium, phosphate,...

Introduction: We report the clinical and radiological features as well outcomes of invasive fungal rhinosinusitis in patients with diabetes from a tertiary care center North India.
 Methodology: All admitted diagnosis pre-existing or newly diagnosed 1st January 2008 to 31st December 2015 were included. Hospital records used identify features, biochemical investigations treatment modalities used. The imaging findings reported at baseline, 30, 60,90 120 days admission progression disease...