A5090435789- Ovarian function and disorders
- Thyroid Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adrenal Hormones and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Reproductive Biology and Fertility
- Parathyroid Disorders and Treatments
- Ovarian cancer diagnosis and treatment
- Pituitary Gland Disorders and Treatments
- Stress Responses and Cortisol
- Medical Imaging and Pathology Studies
- Diabetes Management and Research
- Bone health and treatments
- Liver Disease Diagnosis and Treatment
- dental development and anomalies
- Hypothalamic control of reproductive hormones
- Hormonal Regulation and Hypertension
- Hormonal and reproductive studies
- Retinal and Optic Conditions
- Thyroid Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Autoimmune Bullous Skin Diseases
- Statistical Methods in Epidemiology
Government Medical College
2017-2024
Government Medical College and Hospital
2021-2024
National Institute for Research in Reproductive Health
2024
Indian Council of Medical Research
2024
Government Medical College
2021-2023
University of Calicut
2021
Fiji National University
2021
Physiological Society
2021
Government Medical College
2021
Government Medical College
2009-2011
Both type 2 diabetes and hypothyroidism are highly prevalent disorders in the community. The existing data regarding prevalence of patients with comes mostly from small studies. There only two studies a sample size more than 1000 diabetic patients, none which have been done South Asians. present study evaluated for presence clinical factors associated it. demographic, anthropometric, clinical, biochemical parameters consecutively enrolled were systematically collected analyzed. A total 1152...
To define acute optic neuritis following infection with chikungunya virus (CHIKV) and to determine the efficacy of treatment corticosteroids neuritis.This was an observational study involving 10 patients, who were confirmed cases CHIKV in one or both eyes. A complete ophthalmic examination performed all cases. All patients treated intravenous methylprednisolone for 3 days, followed by oral prednisolone 2 weeks, thereafter reducing dose over 1 month.Of study, seven male three female. Seven...
OBJECTIVE To derive macronutrient recommendations for remission and prevention of type 2 diabetes (T2D) in Asian Indians using a data-driven optimization approach. RESEARCH DESIGN AND METHODS Dietary, behavioral, demographic assessments were performed on 18,090 adults participating the nationally representative, population-based Indian Council Medical Research–India Diabetes (ICMR-INDIAB) study. Fasting 2-h postglucose challenge capillary blood glucose glycosylated hemoglobin (HbA1c)...
Importance The prevalence of polycystic ovary syndrome (PCOS) varies across the globe. Indian studies on PCOS are limited by poor design, small sizes, regional representations, and varying methods. Objectives To estimate nationwide in India, examine phenotypic spectrum, assess magnitude comorbidities associated with PCOS. Design, Setting, Participants This cross-sectional study recruited 9824 women aged 18 to 40 years from November 1, 2018, July 31, 2022, 5 zones country. A prevalidated...
Primary tuberculous osteomyelitis of the sternum is a rare clinical entity. Sternal tuberculosis can result from direct extension disease hilar lymph nodes, hematogenous or lymphatic dissemination other sites, and following BCG vaccination in children. An unusual case primary that presented with swelling pain over manubrium sterni reported. Diagnosis was confirmed by demonstration epithelioid granulomas acid-fast bacilli positive M. culture aspirate taken sternal swelling. Extensive...
Key Messages:Octreotide can be used as an adjunctive therapy to increase phosphorus levels in patients with tumor-induced osteomalacia. Malignant phosphaturic mesenchymal tumor (PMT) may benefit from treatment peptide receptor radionucleotide therapy.
Objectives Injectable tetracosactide hexa-acetate, ACTH 1-24 (Synacthen), is not marketed in many countries including India, whereas long acting porcine sequence, 1-39 (Acton Prolongatum ® ) easily available and much cheaper. This study aimed to find the diagnostic accuracy of stimulation test using i.m. Acton (acton prolongatum test, APST) comparison with Synacthen (short synacthen SST) for diagnosis glucocorticoid insufficiency. Methods Subjects a suspicion adrenal insufficiency based on...
Reduction of atherosclerotic cardiovascular disease (ASCVD) risk in patients with diabetes requires proper management lipid parameters. This study aimed to find the pattern dyslipidemia and scope ASCVD reduction by management.Clinical, biochemical, medication profiles all attending a tertiary care hospital over 2-year period were collected. The prevalence various abnormalities was determined after excluding thyroid dysfunction those on lipid-lowering medications. Patients stratified...
A BSTRACT Background: There are no guidelines on individualized initial levothyroxine dosage in primary hypothyroidism. This prospective observational study was done to assess whether a predetermined dose of based Thyroid Stimulating Hormone (TSH) levels would be able make the patient euthyroid during period six weeks and find other factors which influence requirement. Materials Methods: Newly diagnosed patients with hypothyroidism or those who were not therapy divided into TSH-based...
Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders largely affecting women reproductive age group. Objectives: This study aimed to understand Indian public health-care systems’ preparedness in addressing PCOS. Materials and Methods: A multicentric rapid assessment cross-sectional was undertaken among 173 providers serving across various facilities India. a component larger task force that estimate community-based prevalence PCOS Information on cases...
There is scanty data in India on polycystic ovary syndrome (PCOS) from several small, undersized, convenience-based studies employing differing diagnostic criteria and reporting varied regional prevalence. It difficult to draw clear-cut conclusions these studies; therefore, the present multicentric, well-designed, large-scale representative countrywide epidemiological study PCOS across was conceived with aim generate actual prevalence rates of a total sample size approximately 9000 individuals.
The hormonal profile varies considerably with age, gender, ethnicity, diet or physiological state of an individual. Limited population-specific studies have studied the variations in parameters among apparently healthy women. We aimed to analyse biological reference interval for various reproductive-aged Indian women.Out 3877 participants that were clinically evaluated, 1441 subjects subjected laboratory investigations. All underwent a detailed clinical, biochemical and profiling. hormone...
A clear understanding of the anthropometric and sociodemographic risk factors related to BMI hypertension categories is essential for more effective disease prevention, particularly in India. There a paucity nationally representative data on dynamics these factors, which have not been assessed among healthy reproductive-age Indian women.This cross-sectional polycystic ovary syndrome (PCOS) task force study aimed assess characteristics women explore association with various noncommunicable...
Recent studies have shown a high prevalence of Type-2-diabetes (T2DM) (24%) and prediabetes (18.1%) in Kerala. There is no community based study from South Asia regarding the type 2 diabetes its precursors young adult population. This was done to find Indian youth (18-30 years age) Thiruvananthapuram district.Cross sectional design used for this study. Multistage cluster sampling enrol dwelling 18 30 years, residing district. Six panchayath wards rural urban regions 4 coastal area were...
Abstract Background Synacthen stimulated salivary cortisol has been previously evaluated and found beneficial in the diagnosis of adrenal insufficiency (AI), especially situations with altered cortisol‐binding protein (CBG) levels. Unfortunately, is not marketed many parts world whereas porcine sequence corticotrophin (Acton Prolongatum) readily available. This study aimed to find diagnostic accuracy Acton prolongatum test (APSST) compared short synacthen (SST). Methods Consecutive...
Abstract Background Late-night salivary cortisol (LNSC) is used as a screening test for Cushing syndrome (CS), but there no community-derived normative data the normal upper limit in South Asian population. This study aimed to determine of (97.5th percentile) LNSC an Indian population using commercially available second-generation electrochemiluminiscence immunoassay (ECLIA). Methods apparently healthy community-dwelling individuals was assessed by multistage cluster sampling. Healthy age 18...
ABSTRACT Iodine, an essential micronutrient, is crucial for the production of thyroid hormones - triiodothyronine(T3) and thyroxine(T4). Thyroid regulate optimum mental development, physical growth regulation body metabolism, heat generation, maintenance temperaturein individual. Geological processes like flooding, soil erosion, deforestation, rivers changing course, deplete surface iodine, as it present in top layers easily soluble water. As a result, population residing area with...