PURPOSE: To comparatively investigate changes in epithelial thickness between myopic femtosecond laser–assisted LASIK (FS-LASIK) and small incision lenticule extraction (SMILE). METHODS: This study compared the topographic 175 eyes undergoing FS-LASIK (62 eyes) or SMILE (113 eyes). Epithelial was obtained using spectral-domain optical coherence tomography before surgery 1 3 months after surgery. Topographic by automatic algorithm variability (standard deviation over 17 imaged areas) two...

ABSTRACT PURPOSE: To compare central corneal thickness measurements obtained in unoperated eyes and after myopic photorefractive keratectomy (PRK) using a rotating Scheimpflug camera (Pentacam), scanning slit topography system (Orbscan II), ultrasonic pachymetry. METHODS: Corneal was measured Pentacam, Orbscan II, pachymetry 25 (unoperated group), 24 1 to 3 months PRK (early postoperative 21 4 or more (late group). RESULTS: In the group, were similar for all three methods (P =.12 5). early...

To investigate topographic changes in corneal epithelial thickness (CET) and stromal following orthokeratology (OK) to determine associated factors affecting refractive changes.This study investigated the CET 60 myopic eyes that were fitted with OK lenses. obtained using spectral-domain optical coherence tomography (OCT) before after lens wear. Changes error topography data obtained. The correlation between change change, various refractive, lens, parameters analyzed simple regression...

Purpose: This study aimed to evaluate the prediction accuracy of four intraocular lens (IOL) power calculation formulas; Barrett Universal II, SRK/T, Hoffer-QST, and Kane, using conventional keratometry (K) total (TK) in patients who underwent implantation a four-haptic hydrophobic multifocal IOL (Artis Symbiose Plus<sup>®</sup>).Methods: We analyzed 26 (32 eyes) cataract surgery with Artis Plus<sup>®</sup>. Preoperative biometric data, including axial length,...

Purpose: To assess the accuracy and validity of true net corneal power Pentacam system to provide a keratometry reading for calculating intraocular lens (IOL) in postoperative refractive surgery eyes. Methods: Refraction, an automated reading, were measured 30 eyes that required cataract had previously undergone surgery. Target refraction values calculated with SRK/T formula using compared manifest values. Results: Using power, mean deviation from desired outcome was 0.47±0.56 diopters (D);...

To compare the efficacy of topical cyclosporine 0.05% (tCsA) and combined treatment with 1% methylprednisolone acetate for moderate-to-severe chronic dry eye.Forty-four patients eye who had not responded to conventional were treated tCsA 3 months. Twenty-one subjects (Group 1) methyl prednisolone initial weeks, only thereafter, 23 2) only. Symptom scores, tear break-up time (TBUT), Schirmer score, corneal conjunctival fluorescein staining evaluated before at 1, 2, months after treatment....

Purpose: To compare the measurements of posterior corneal elevation above best-fit sphere before and after photorefractive keratectomy (PRK) using two different technologies—Scheimpflug imaging Pentacam (Oculus) scanning slit combined with Placido Orbscan II (Bausch & Lomb). Methods: In a retrospective observational case series study, 60 eyes measured or PRK were evaluated. The data analyzed as three groups: preoperative, early postoperative (from 1 to 3 months surgery), late (>3...

Purpose: Fibroblast activation may play an important role in pterygium progression. Synthetic peroxisome proliferator-activated receptor γ (PPAR-γ) ligands have been shown to be effective antifibrotic agents against transforming growth factor β1 (TGF-β1) induced fibrosis several tissues. We aimed investigate the effects of PPAR-γ ligand rosiglitazone fibroblasts and underlying mechanisms. Methods: Profibrotic was by TGF-β1 primary cultured human effect treatment on α-smooth muscle actin...

To describe current cataract surgery practice patterns and changing trends among Korean ophthalmologists.A survey of members the Society Cataract Refractive Surgery was performed in July 2018. One hundred two (12.7%) 801 questionnaires were returned for analysis. The data analyzed using descriptive statistics compared with previous surveys.Most respondents (75%) had been 6 or more years an average 31 surgeries per month. preferred method phacoemulsification (95%); 5% used a femtosecond...

In case of focal neuropathy, the muscle fibers innervated by corresponding nerves are replaced with fat or fibrous tissue due to denervation, which results in increased echo intensity (EI) on ultrasonography. EI analysis can be conducted quantitatively using gray scale analysis. Mean value pixel brightness image defined as EI. However, accuracy achieved this parameter alone differentiate between normal and abnormal muscles is limited. Recently, attempts have been made increase artificial...

Purpose: To measure the corneal epithelial thickness (CET) and stromal (ST) in normal subjects, to also evaluate their correlation with gender, age, myopia severity. Methods: A total of 162 subjects were enrolled; they divided into 3 groups based on refractive status: "low myopia" (−0.25 −3.0 D), "moderate (−3.0 −6.0 "high (more than D). The CET obtained using optical coherence tomography, regional thicknesses topographic variability compared among between men women. Furthermore,...

Purpose: Profibrotic activation is essential for pterygium development. In this study, we investigated the role of mechanistic target rapamycin (mTOR) in regulating TGF-β1-induced myofibroblastic responses human fibroblasts (HPFs) and elucidated relative contributions mTOR signaling components. Methods: HPFs were pretreated with inhibitors Torin2, expression profibrotic markers, including α-smooth muscle actin (α-SMA) fibronectin, was evaluated. RNA interference-based approaches targeting...

Purpose: We sought to evaluate the distribution and characteristics of meibomian gland dysfunction (MGD) treatment patterns for symptomatic MGD patients in South Korea.Methods: One hundred ninety-six right eyes 196 were enrolled.For each patient, meibum expressibility central eight glands both upper lower eyelids was examined.Each eyelid separately classified into one following three subtypes: nonobvious obstructive (low-delivery without lid margin abnormality), obvious with hypersecretory...

Purpose: To describe the clinical features of homozygous granular corneal dystrophy type II (GCDII) with age and several kinds treatment in 18 patients different conditions. Methods: Eighteen GCDII patients, confirmed DNA analysis, 13 families were enrolled. Their that include at detection by parents, visual acuity, disease progression evaluated. We also studied recurrence patterns for who underwent phototherapeutic keratectomy, penetrating keratoplasty, lamellar or deep keratoplasty....

Purpose: The purpose of this study was to evaluate changes in the posterior corneal surface before and after laser ablation using Pentacam. Methods: Thirty consecutive myopic eyes having (14 photorefractive keratectomies, 16 laser-assisted subepithelial keratectomies) were evaluated preoperatively postoperatively with Changes curvature, elevation, anterior chamber depth measured. Results: 30 had a mean correction -4.50 D (range, -2.12 -8.0) 58.4 μm 21-106 μm). change curvature -0.02 ± 0.07...

Purpose: To compare corneal sensitivity and recovery of innervation between temporal superior clear incisions in cataract surgery. Methods: We compared the change patients with who had received phacoemulsification using either (group 1) or 2). The changes were measured at 1 week, month, 3 months after surgery Cochet-Bonnet esthesiometer. For a different study population, 25 eyes 20 nerve density confocal microscopy undergone also assessed. All parameters preoperatively Results: There was...

To assess the nationwide rate of acute postoperative endophthalmitis (APE) after cataract extraction in Korea and to evaluate potential risk factors thereof.Nationwide insurance claims data from July 2014 June 2017 were reviewed. All patients with phacoemulsification or extracapsular/intracapsular included. Exclusion criteria combined glaucoma surgery total vitrectomy when patient had a history intraocular foreign body.In total, 1505103 cases (982203 patients) APE developed 953 (938 an...

To determine the prevalence and risk factors of epiretinal membrane (ERM) utilising spectral-domain optical coherence tomography (SD-OCT).We investigated data from 2017 to 2018 Korea National Health Nutrition Examination Survey. Individuals aged ≥40 years with readable fundus photographs SD-OCT results were included. ERM was diagnosed by photography OCT. The following collected: demographics, health interview, examination, nutritional survey results. estimated for analysed.A total 6807...

The aim of this study was to predict the mean corneal power change preoperatively for simultaneous pterygium excision and cataract extraction.This performed in 2 stages. First, 66 eyes undergoing were recruited, subjects divided into groups based on a length 2.0 mm (group 1: <2.0 mm, group 2: ≥2.0 mm). Keratometric values (K) measured before, 1 month after, 3 months after surgery. Multiple regression analyses used postoperative K using preoperative morphological factors that significantly...

Corneal thickness measurement is important for assessing intraocular pressure in patients with glaucoma. This study investigated the changes corneal epithelial (CET) induced by antiglaucoma medications and explored factors affecting CET measurement. was measured over a 9.0 mm diameter area using Fourier domain optical coherence tomography 125 primary open-angle glaucoma age-matched controls without The influence of sex, age, benzalkonium chloride (BAK)-containing instillations, disease...