Chao Zhang

ORCID: 0000-0001-5307-8061
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About
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Research Areas
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Central Venous Catheters and Hemodialysis
  • Vascular Procedures and Complications
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Venous Thromboembolism Diagnosis and Management
  • Dialysis and Renal Disease Management
  • Gastroesophageal reflux and treatments
  • Immunodeficiency and Autoimmune Disorders
  • Cancer-related molecular mechanisms research
  • Renal function and acid-base balance
  • Seaweed-derived Bioactive Compounds
  • Fibroblast Growth Factor Research
  • Tuberculosis Research and Epidemiology
  • Eosinophilic Esophagitis
  • Cardiovascular Health and Disease Prevention
  • Helicobacter pylori-related gastroenterology studies
  • Liver Disease and Transplantation
  • Pneumonia and Respiratory Infections
  • MicroRNA in disease regulation
  • Heart Failure Treatment and Management
  • Advanced Glycation End Products research

Capital Medical University
2014-2025

Beijing Children’s Hospital
2025

Beijing Chao-Yang Hospital
2019-2024

Second Artillery General Hospital of Chinese People's Liberation Army
2016

People's Hospital of Bishan District
2005

Acute kidney injury (AKI) is common in hospitalized children. A post-AKI outcomes prediction model important for the early detection of clinical associated with AKI so that management pediatric patients can be initiated. Three retrospective cohorts were set up based on two hospitals China, which 8205 children suffered during hospitalization. Two evaluated, i.e. hospital mortality and dialysis within 28 days after occurrence. Genetic Algorithm was used feature selection, a Random Forest built...

10.1093/ckj/sfaf007 article EN cc-by-nc Clinical Kidney Journal 2025-01-09

Diabetic cardiomyopathy (DCM) is characterized by cardiac dysfunction and cardiomyocyte apoptosis. Oxidative stress suggested to be the major contributor development of DCM. This study was intended evaluate protective effect low molecular weight fucoidan (LMWF) against in diabetic rats. Type 2 goto-kakizaki rats were untreated or treated with LMWF (50 100 mg/kg/day) for three months. The establishment DCM model effects on function evaluated echocardiography isolated heart perfusion....

10.1155/2014/420929 article EN cc-by Journal of Diabetes Research 2014-01-01

Background: Patients in maintenance hemodialysis (MHD) need a patent vascular access for optimal treatment. Autologous arteriovenous fistula (AVF) is the patients with MHD. However, AVF dysfunction may limit its use. The aim of this article to explore factors associated primary

10.21037/apm-20-2196 article EN Annals of Palliative Medicine 2021-04-01

Background/Aims Respiratory symptoms are often associated with gastroesophageal reflux disease (GERD). Although the role of multichannel intraluminal impedance–pH (MII-pH) monitoring in GERD is clear, little known regarding characteristics patients respiratory based on MII-pH and anti-reflux therapy. We evaluated a cohort to identify parameters GERD-related assess therapy outcomes. Methods undertook prospective study who were referred for evaluation from January 2011 2012. One hundred...

10.1371/journal.pone.0160139 article EN cc-by PLoS ONE 2016-08-17

Abstract Background The present study aimed to explore the functions and molecular mechanisms of miR‐511 in breast cancer. Methods A quantitative real‐time polymerase chain reaction (qRT‐PCR) was used detect levels cancer tissues; a chi‐squared test analyze relationship between expression level pathological parameters patients; proliferation cell lines MDA‐MB‐231 MCF‐7 determined by counting kit‐8 (CCK‐8) assay; migration scratch wound healing assay transwell TargetScan predict binding site...

10.1002/jgm.3168 article EN The Journal of Gene Medicine 2020-02-05

Pneumocystis pneumonia (PCP) remains a common opportunistic infection in immunosuppressed individuals. Current studies showed that multiple immune cells and cytokines took part the host defense against (PC). However, roles of IL-17 IL-10 development PCP have not been elucidated.IL-10 levels serum from mice were detected via ELISA. The percentages B10 cells, IL-10+ macrophages, T lung IL-17-/- Th17 IL-17+γδT IL-10-/- examined flow cytometry. Also, antibody neutralization examination was also...

10.1155/2019/6750861 article EN cc-by Mediators of Inflammation 2019-09-10

Abstract Pneumocystis pneumonia (PCP) is a common opportunistic infection that occurs in immunocompromised patients. Compared with HIV patients, PCP non-HIV patients tends to follow up more urgent course and poorer prognosis. Therefore, markers could predict survival of population are great value. MiRNA-150 has been widely studied many diseases since it identified as vital regulator immune cell differentiation activation. We thus conduct this study aiming evaluate the prognostic value...

10.1093/mmy/myae022 article EN Medical Mycology 2024-03-12
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