Jukun Wang

ORCID: 0000-0003-4332-5211
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About
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Research Areas
  • Aerodynamics and Fluid Dynamics Research
  • Fluid Dynamics and Vibration Analysis
  • Central Venous Catheters and Hemodialysis
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Ferroptosis and cancer prognosis
  • Vascular Procedures and Complications
  • Cancer, Lipids, and Metabolism
  • Physics of Superconductivity and Magnetism
  • Magnetic Bearings and Levitation Dynamics
  • Spacecraft and Cryogenic Technologies
  • Cancer Mechanisms and Therapy
  • Frequency Control in Power Systems
  • Wind and Air Flow Studies
  • Vascular Malformations Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Corrosion Behavior and Inhibition
  • Pancreatic and Hepatic Oncology Research
  • Liver physiology and pathology
  • RNA modifications and cancer
  • Dialysis and Renal Disease Management
  • Renal and Vascular Pathologies
  • Cerebrovascular and Carotid Artery Diseases
  • Refrigeration and Air Conditioning Technologies
  • Renal cell carcinoma treatment

Capital Medical University
2018-2024

Southwest Jiaotong University
2020-2023

Xuan Wu Hospital of the Capital Medical University
2022

Abstract The evacuated tube transportation has great potential in the future because of its advantages energy saving and environmental protection. train runs closed at ultra-high speed. heat quantity generated by aerodynamic heating is not easy to spread external environment then accumulates tube, inducing ambient temperature rise gradually. In this paper, a three-dimensional geometric model Shear Stress Transport (SST) κ-ω turbulence are used study influence initial on structure flow field...

10.1186/s42774-020-00053-8 article EN cc-by Advances in Aerodynamics 2020-12-01

Controlled generation of cytotoxic reactive oxygen species (ROS) is essential in cancer therapy. Ultrasound (US)-triggered sonodynamic therapy (SDT) has shown considerable ability to trigger

10.3389/fimmu.2024.1339380 article EN cc-by Frontiers in Immunology 2024-03-20

Background: Patients in maintenance hemodialysis (MHD) need a patent vascular access for optimal treatment. Autologous arteriovenous fistula (AVF) is the patients with MHD. However, AVF dysfunction may limit its use. The aim of this article to explore factors associated primary

10.21037/apm-20-2196 article EN Annals of Palliative Medicine 2021-04-01

Background: Several studies have indicated that CXC chemokines influence the prognosis and therapy in patients with hepatocellular carcinoma (HCC). However, there are limited on roles of HCC based data acquired from various databases. This study aimed to conduct an in-depth comprehensive bioinformatic analysis expression functions HCC.

10.21037/tcr-21-127 article EN Translational Cancer Research 2021-05-01

Abstract We wished to construct a prognostic model based on ferroptosis-related genes and simultaneously evaluate the performance of analyze differences between high-risk low-risk groups at all levels. The gene-expression profiles relevant clinical data patients with non-small-cell lung cancer (NSCLC) were downloaded from public databases. Differentially expressed (DEGs) obtained by analyzing tissues paracancerous tissues, common DEGs identified as candidate genes. Next, risk-score was...

10.1042/bsr20210527 article EN cc-by Bioscience Reports 2021-05-01

The aim of this study was to elucidate the association between apolipoprotein A-I (Apo A-I) and overall survival (OS) as well cancer-specific (CSS) in non-muscle-invasive bladder cancer (NMIBC) patients undergoing transurethral resection tumor (TURBT).We retrospectively collected data 470 eligible diagnosed with NMIBC who received TURBT January 2004 December 2011. Pretreatment blood indexes were examined. Apo clinicopathological characteristics further analyzed by dichotomizing our sample...

10.2147/cmar.s165213 article EN cc-by-nc Cancer Management and Research 2018-05-01

The levitation force in the high temperature superconducting (HTS) maglev system has obvious nonlinear characteristics. When excitation frequency and amplitude meet certain conditions, vibration phenomena such as period-doubling bifurcation would appear. Nonlinear will bring difficulties to dynamic analysis even affect safety comfort of driving. While an electromagnetic shunt damper (EMSD) can effectively reduce amplitude. This paper analyzes influence EMSD on HTS systems from perspective...

10.1109/tasc.2021.3094442 article EN IEEE Transactions on Applied Superconductivity 2021-07-02

The objective of this study is to investigate the safety high temperature superconducting (HTS) high-speed maglev trains operating in an open environment subjected strong crosswinds. Therefore, a full-size numerical model HTS engineering prototype developed based on 3-D, steady RANS method and SST k-ω turbulence model. Then, aerodynamic loads are added simplified loading center train, dynamic vehicle basis special nonlinear magnetic-track relationship established variation indexes train...

10.1177/09544062221140033 article EN Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science 2022-12-04

High-temperature Superconducting (HTS) maglev trains are vulnerable to the effects of crosswinds when operating at high speeds in open-air conditions, potentially compromising riding comfort and safety. This study established a vehicle dynamic model based on nonlinear maglev-track relationship added aerodynamic loads under train’s simplified load center address this issue. Using maximum vibration acceleration limit Sperling index, we evaluated HTS train different conditions. Further, power...

10.3390/su152316511 article EN Sustainability 2023-12-03

Abstract Purpose: ADME genes are involved in drug absorption, distribution, metabolism, and excretion (ADME). Previous studies report that expression levels of ADME-related correlate with prognosis hepatocellular carcinoma (HCC) patients. However, the role gene on HCC has not been fully explored. The present study sought to construct a prediction model using for HCC. Methods: Transcriptome clinical data were retrieved from Cancer Genome Atlas (TCGA) International Consortium (ICGC), which...

10.1042/bsr20210583 article EN cc-by Bioscience Reports 2021-05-01

Ferroptosis has been found to affect the prognosis and immunotherapy of hepatocellular carcinoma (HCC). However, association between ferroptosis-related genes infiltrating immune cells in tumor microenvironment (TIME) not fully elucidated. This study aimed at establishing a prediction model for progression HCC using ferroptosis-associated based on score.Transcriptomic, mutation clinicopathological information were downloaded from TCGA International Cancer Genome Consortium (ICGC) this study....

10.21037/jgo-21-237 article EN Journal of Gastrointestinal Oncology 2021-10-01

Background: Arteriovenous fistula (AVF) was the lifeline of patients with maintenance hemodialysis (MHD). However, stenosis AVF may limit its use. Currently, is commonly treated balloon angioplasty. Meanwhile, several balloons were available. Therefore, this study aimed to explore effectiveness angioplasty five different in stenosis.

10.21037/apm-21-2898 article EN Annals of Palliative Medicine 2022-05-17

Aim: During the development of atherosclerosis, vascular smooth muscle cells (SMCs) undergo phenotypic switching from contractile phenotype to synthetic phenotype. This study aimed at examining role DNA modification mediated by oxidative stress dependent ten eleven translocation enzymes (TETs) expression early stage switching.

10.5551/jat.55343 article EN Journal of Atherosclerosis and Thrombosis 2020-09-24

Previous research indicates that hypoxia critically affects the initiation and progression of hepatocellular carcinoma (HCC). Nevertheless, molecular mechanisms responsible for HCC development are poorly understood. Herein, we purposed to build a prognostic model using hypoxia-linked genes predict patient prognosis investigate relationship with immune status in tumor microenvironment (TME).The training cohort included transcriptome along clinical data abstracted from The Cancer Genome Atlas...

10.21037/tcr-21-741 article EN Translational Cancer Research 2021-09-01

The high degree of heterogeneity hepatocellular carcinoma (HCC) imposes a significant challenge to predict the prognosis. Currently, increasing evidence has indicated that cell cycle-linked genes are strongly linked occurrence and progress HCC. Herein, we purposed create prediction model on basis genes.The transcriptome along with clinicopathological data abstracted from Cancer Genome Atlas (TCGA) were used as training cohort. Lasso regression analysis was employed in TCGA samples obtained...

10.21037/tcr-21-1145 article EN Translational Cancer Research 2021-11-01

Autologous arteriovenous fistula (AVF) is preferred in hemodialysis patients. Maintaining its patency a critical problem. This study aimed to create nomogram model for predicting 1-year primary of AVF. Consequently, total 414 patients were retrospectively enrolled and randomly allocated training validation cohorts. Risk factors identified by multivariable logistic regression used model. Performance the was evaluated receiver operating characteristic (ROC) curve, Hosmer-Lemeshow test,...

10.1016/j.isci.2024.110727 article EN cc-by-nc iScience 2024-08-15

High-temperature superconducting (HTS) Maglev-Evacuated tube transport (HTS Maglev-ETT) has the advantages of high speed, safety, energy saving, and environmental protection. In this system, aerodynamic characteristics are very crucial for its design practical application. paper, series three-dimensional models different working conditions were established, HTS Maglev-ETT system studied with utilization ANSYS FLUENT software. It found that under low pressure block ratio, drag train is small,...

10.1109/asemd49065.2020.9276332 article EN 2020-10-16

The high temperature superconducting (HTS) maglev–evacuated tube transport (ETT) system is deemed as the next-generation system, with potential to realize ultra-high speed. When HTS maglev train travels inside closed tube, it can cause serious aerodynamic thermal problems that affect traffic safety. In this paper, a three-dimensional model and Reynolds Average Navier-Stokes (RANS) based on <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SST...

10.1109/tasc.2021.3099776 article EN IEEE Transactions on Applied Superconductivity 2021-07-26
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