M Stepanova
A5034205111- Breast Cancer Treatment Studies
- Renal cell carcinoma treatment
- Pancreatic and Hepatic Oncology Research
- Advanced Breast Cancer Therapies
- PI3K/AKT/mTOR signaling in cancer
- Colorectal Cancer Treatments and Studies
Krasnoyarsk State Pedagogical University
2020-2022
State Budget Institution of Health St. Petersburg Clinical Research Center Specialized Types of Medical Care
2019
Background. By 2020, breast cancer (BC) has become the most frequent malignancy in world. The common type of BC is HR+/HER2-negative cancer,2540% which harbors PIK3CA mutations that affect catalytic subunit PI3K protein. alterations are actionable, as such neoplasms can be treated with a combination fulvestrant and inhibitor alpelisib. As have an extremely versatile effect on characteristics tumor cell, numerous associations various clinico-pathological traced.
 Aim. Our aim was to...
Introduction. The results of randomized MPACT study have demonstrated that the addition nab-paclitaxel to gemcitabine leads a statistically significant increase in life expectancy. main objective this retrospective was obtain up-to-date efficacy and toxicity data for drug combination Russian real-world clinical setting. Materials methods . enrolled patients with morphologically confirmed locally advanced or metastatic pancreatic cancer who had ECOG Performance Status scores 0-2 received...