A5056180851- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Ureteral procedures and complications
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Botulinum Toxin and Related Neurological Disorders
- Renal and Vascular Pathologies
- Organ Donation and Transplantation
- Spinal Dysraphism and Malformations
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Renal cell carcinoma treatment
- Prostate Cancer Treatment and Research
- Renal Transplantation Outcomes and Treatments
- Neurological Complications and Syndromes
- Sexual function and dysfunction studies
- Health, Medicine and Society
- Urologic and reproductive health conditions
- Multiple Sclerosis Research Studies
- Systemic Sclerosis and Related Diseases
- Anorectal Disease Treatments and Outcomes
- Renal and related cancers
- Genetic and Kidney Cyst Diseases
Hôpital Rangueil
2016-2025
Centre Hospitalier Universitaire de Toulouse
2016-2025
Université de Toulouse
2015-2024
Metabolism and Renal Physiology
2010-2023
Université Toulouse III - Paul Sabatier
2014-2022
Assistance Publique – Hôpitaux de Paris
2022
Inserm
2011-2021
Centre d’Investigation Clinique 1436
2020
Conseil Régional du Languedoc-Roussillon
2020
CRV (Netherlands)
2020
Abstract Aims Electrostimulation is an established therapeutic option for neurogenic urinary disorders. The aim of this study was to investigate the efficacy noninvasive technique transcutaneous posterior tibial nerve stimulation (TPTNS) in patients with multiple sclerosis (MS) and troublesome symptoms overactive bladder (OAB). Methods A multicentric enrolled 70 MS patients, suffering from OAB a 3‐month period. Intervention : Daily sessions 20 min TPTNS were provided. No change associated...
We compared the morbidity and mortality of laparoscopic vs open surgery in radical cystectomy for bladder cancer.This prospective, nonrandomized study was conducted between January 2003 July 2007 68 patients (7 women 61 men) who underwent cancer. A total 38 cystectomies were performed laparoscopically 30 by surgery. Mean patient age 68.0 +/- 9.0 years. Median preoperative American Society Anesthesiologists score 2 (range 1 to 3) both groups.Intraoperative blood loss transfusion rate...
The efficacy of sacral neuromodulation for treating refractory idiopathic lower urinary tract dysfunction is now well established. Nevertheless, results this technique in neurological patients are still controversial. aim retrospective study was to assess the neurogenic bladder dysfunction.Between 1998 and 2008, a percutaneous nerve evaluation or two-stage performed 62 (mean age 50.5 ± 14.8 years) with dysfunction. Before during temporary stimulation, each patient had urodynamic diary. test...
We studied the effect of repeat detrusor botulinum neurotoxin type A injections on urinary symptoms, health and quality life in patients with refractory neurogenic overactivity secondary to multiple sclerosis.This was a prospective, open label, single center study 137 sclerosis treated observations made from 2002 2009. minimally invasive outpatient technique used for injection. Patients were asked contact department if when they required treatment. Recurrent then identified urodynamics. The...
We evaluated the morbidity of radical cystectomy for invasive bladder cancer in select patients older than 75 years using recent data from 2 academic hospitals.We analyzed 73 cystectomies performed January 1995 to June 2000 89 old (median age 79.3). Cases were categorized according American Society Anesthesiologists classification with a score 41, 3 30 and 4 2. External urinary diversion was 51 cases an ileal neobladder constructed 22. incidence type complications, clinical outcome,...
To assess results and morbidity of the periprostatic insertion an artificial urinary sphincter (AUS) in adult male patients with a neurogenic bladder.A retrospective study was carried out on 51 operated four urologic academic wards from April 1988 to January 2008. Among these patients, 31% (16/51) had spina bifida 69% (35/51) spinal cord injury. All suffered incontinence secondary sphincteric deficiency, this associated detrusor overactivity 39% them (leading cases added bladder...
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease characterized by visceral pain and voiding symptoms. IC/BPS still an unsolved enigma with ineffective diagnosis criteria treatment. A main limitation in understanding the lack of appropriate preclinical model. Cyclophosphamide (CYP) commonly used as experimental model for rodent. However, proposed models are very aggressive, contrasting what occurs clinic, often associated severe toxicity high mortality...
The reoperation rate for artificial urinary sphincters (AUS) in men is about 25%, with poorer survival rates when reimplantation occurs after urethral erosion or infection. Data on the outcomes of second AUS implants are rare, and no data exist third implants. We aimed to evaluate functional a two previous explantations. records all patients implanted between 2006 2023 seven French university hospitals were reviewed retrospectively. Only following cuff explantations revisions included....
While interstitial cystitis along with bladder pain syndrome (IC/BPS) is still poorly treated, published clinical evidence suggests that onabotulinumtoxinA (natural botulinum neurotoxin type A (BoNT/A)) intradetrusor injections efficient in IC/BPS. However, as instillation could be a safer and more convenient administration route, we aimed to investigate the effect of BoNT/A needle-free an IC/BPS rodent model. Cyclophosphamide (CYP) was used induce rats. The resulting symptoms mimicked main...
Abstract Scarce data exist regarding the incidence of donor‐specific antibodies ( DSA s) in kidney transplant patients receiving everolimus‐based immunosuppression without calcineurin inhibitors CNI s). The aim this retrospective case–control study was to compare de novo s converted an regimen with that seen maintained on s. Sixty‐one ‐free who had been (everolimus group) were compared 61 other s‐based (control group). Patients matched according age, gender, induction therapy, date...
This is the first report of graft function and prostate cancer control in renal transplant recipients subjected to modern conformal radiotherapy.Eight kidney were treated with three-dimensional radiotherapy. All patients but one transitory hormonal deprivation. A radiotherapy-planning system (Pinnacle, Philips Medical System, Bothell, WA) was used delineate anatomic contours on pretreatment computed tomography for dose computation. The clinical target volume encompassed expanded a 10-mm wide...
Neurogenic bladder dysfunction has a negative impact on the patient's quality of life (QoL). Cystectomy with ileal conduit urinary diversion is treatment option in patients failure after conservative management. The objective this study was to evaluate QoL neurogenic dysfunction.From March 2004 November 2010, 48 (36 women and 12 men mean age 50.6 ± 11.8 years) treated by cystectomy for dysfunction, prospectively completed, before surgery, two self-administered questionnaires. Neurological...