A5048910110- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Urinary Bladder and Prostate Research
- Transcranial Magnetic Stimulation Studies
- Pelvic floor disorders treatments
- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- Health, Medicine and Society
- Neural dynamics and brain function
- Motor Control and Adaptation
- Systemic Sclerosis and Related Diseases
- Neurological disorders and treatments
- Multiple Sclerosis Research Studies
- Visual perception and processing mechanisms
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Healthcare Systems and Practices
- Spatial Neglect and Hemispheric Dysfunction
- Nerve Injury and Rehabilitation
- Peripheral Nerve Disorders
- Parkinson's Disease Mechanisms and Treatments
- Balance, Gait, and Falls Prevention
- Vestibular and auditory disorders
Université de Toulouse
2014-2024
Inserm
2015-2024
Hôpital Necker-Enfants Malades
2022-2024
Hôpital Pellegrin
2024
Centre Hospitalier Universitaire de Bordeaux
2023-2024
Hôpital Rangueil
2014-2023
Centre de Physiopathologie de Toulouse-Purpan
2012-2023
Centre Hospitalier Universitaire de Toulouse
2002-2023
Université Toulouse III - Paul Sabatier
2011-2023
Assistance Publique – Hôpitaux de Paris
2017-2022
Why does neuronal activity in sensory brain areas sometimes give rise to perception, and not? Although noise is often invoked as the key factor, a portion of this variability could also be due history current state affecting cortical excitability. Here we directly test idea by examining whether phase prestimulus oscillatory causally linked with modulations excitability visual perception. Transcranial magnetic stimulation (TMS) was applied over human cortex induce illusory perceptions...
Visual search--finding a target element among similar-looking distractors--is one of the prevailing experimental methods to study attention. Current theories visual search postulate an early stage feature extraction interacting with attentional process that selects candidate targets for further analysis; in difficult situations, this selection is iterated until found. Although such predict intrinsic periodicity neuronal substrates search, prediction has not been extensively tested human...
The first objective of the study was to determine whether functional magnetic resonance imaging (fMRI) signal correlated with motor performance at different stages poststroke recovery. second assess existence prognostic factors for recovery in early MR images. Eight right-handed patients pure deficit secondary a lacunar infarct localized on pyramidal tract were included. This concerned moderately impaired and handgrip strength finger-tapping speed. fMRI task calibrated flexion-extension...
<b>Objective:</b> The ascending reticular activating system (ARAS) modulates circadian wakefulness, which is preserved in a persistent vegetative state (PVS). Its metabolism preserved. Impairment of the polymodal associative cortices (i.e., precuneus) characteristic PVS where awareness abolished. Because interaction these 2 structures allows conscious sensory perception, our hypothesis was that an impaired functional connectivity between them participates loss perception....
The efficacy of sacral neuromodulation for treating refractory idiopathic lower urinary tract dysfunction is now well established. Nevertheless, results this technique in neurological patients are still controversial. aim retrospective study was to assess the neurogenic bladder dysfunction.Between 1998 and 2008, a percutaneous nerve evaluation or two-stage performed 62 (mean age 50.5 ± 14.8 years) with dysfunction. Before during temporary stimulation, each patient had urodynamic diary. test...
Spontaneous α oscillations (∼10 Hz) have been associated with various cognitive functions, including perception. Their phase and amplitude independently predict cortical excitability subsequent perceptual performance. However, the causal role of phase-amplitude tradeoffs on visual perception remains ill-defined. We aimed to fill this gap tested two clear predictions from pulsed inhibition theory according which are periodic functional inhibition. (1) High-α induces at specific phases, low...
The effects of physiotherapy are difficult to assess in very impaired early stroke patients.The aim the study was characterize impact 4 weeks passive proprioceptive training wrist on brain sensorimotor activation after stroke.Patients with a subcortical ischemic lesion pyramidal tract were randomly assigned control or wrist-training group. All patients had single pure motor hemiplegia severe deficit. group (6 patients) underwent standard Bobath rehabilitation. second, "trained," (7 received...
Background. Paired associative stimulation (PAS) combining peripheral nerve and transcranial magnetic (TMS) have been proposed to induce long-term changes in excitability of the cerebral cortex potentially optimize motor recovery stroke patients. Objective. This pilot study examined whether short-lasting cortical could be induced by a single session PAS within first months after stroke. Methods. Six hemiparetic patients with subcortical were included. The protocol was applied at 1, 5, 12...
<h3>OBJECTIVE</h3> A potent heteronymous group II excitation of quadriceps motor neurons has been recently demonstrated in normal subjects. The present study was undertaken to investigate whether this also contributes spasticity hemiplegic patients. <h3>METHOD</h3> early and late facilitations the H reflex elicited by a conditioning volley common peroneal nerve at three times threshold, attributed non-monosynaptic I excitations respectively, were investigated. comparison drawn between...
Stroke patients have impaired postural balance that increases the risk of falls and impairs their mobility. Assessment is commonly carried out by recording centre pressure (CoP) displacements, but lack data concerning reliability these measures compromises interpretation. The purpose this study was to investigate between-day six CoP-based variables, in order provide i) for monitoring sway weight-bearing asymmetry stroke clinical practice ii) consistent assessment method measurement error...
OBJECTIVE: To assess the motor function of left, supposedly unaffected, limbs patients with an acute right vascular hemiplegia. METHODS: Fifteen hemiplegia and 16 matched healthy controls were studied. Motor left each patient was evaluated on days 20 90 after their stroke using four validated tools (hand dynamometer, isokinetic finger tapping, nine hole peg test). RESULTS: There a significant impairment at day compared controls. The had recovered almost completely stroke. CONCLUSION: These...
Neurogenic bladder dysfunction has a negative impact on the patient's quality of life (QoL). Cystectomy with ileal conduit urinary diversion is treatment option in patients failure after conservative management. The objective this study was to evaluate QoL neurogenic dysfunction.From March 2004 November 2010, 48 (36 women and 12 men mean age 50.6 ± 11.8 years) treated by cystectomy for dysfunction, prospectively completed, before surgery, two self-administered questionnaires. Neurological...
Aims Lower urinary tract dysfunctions (LUTD) are very common in Multiple Sclerosis (MS), have a significant social impact, while the organic impact is discussed. We studied complications and their risk factors our cohort of MS patients, order to improve management LUTD MS. Methods Between 2004 2009, all patients affected by managed for were included retrospective study. epidemiological data (age, gender), clinical (duration MS, EDSS score, progression MS) paraclinical (urinary creatinine...
Electromyographic (EMG) raw signals are sensitive to intrinsic and extrinsic factors. Consequently, EMG normalization is required draw proper interpretations of standardized data. Specific recommendations needed regarding a relevant method for participants who show atypical patterns, such as post-stroke subjects. This study compared three methods ("isometric MVC", "isokinetic MVC kinematic-related") on muscle activations the antagonist-agonist co-contraction index. Fifteen subjects fifteen...
Background and Purpose: Additional therapy may improve poststroke outcomes. Self-rehabilitation is a useful means to increase rehabilitation time. Mechanized systems are usual extend time for motor training. The primary aim was compare the effects of self-rehabilitation using mechanized device with control self-exercises on upper extremity impairment in patients stroke. Methods: Phase III, parallel, concealed allocation, randomized controlled, multicenter trial, 12-month follow-up. Patients...
In standing subjects, we investigated the excitation of quadriceps (Q) motoneurones by muscle afferents from tibialis anterior (TA) and semitendinosus (ST) gastrocnemius medialis (GM). Standing with a backward lean stretches pair (TA Q) they must be co-contracted to maintain balance. Equally, forward posterior (GM ST) co-contracted. We used these conditions enhanced increase influence gamma static on spindle afferents, which enhances background input extrafusal motoneurones. The effects...