A5062951727- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Coffee research and impacts
- Phytochemicals and Antioxidant Activities
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Microencapsulation and Drying Processes
- Polysaccharides Composition and Applications
- Pancreatic function and diabetes
- Memory and Neural Mechanisms
- Extracellular vesicles in disease
- Amino Acid Enzymes and Metabolism
- Tryptophan and brain disorders
- Retinal Development and Disorders
- GABA and Rice Research
- Tea Polyphenols and Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Freezing and Crystallization Processes
- Food composition and properties
- Biomedical Research and Pathophysiology
- Circular RNAs in diseases
- Agricultural and Food Sciences
Universidad Autónoma de Guerrero
2014-2024
Corporación Universitaria Iberoamericana
2023
Consejo Nacional de Humanidades, Ciencias y Tecnologías
2019-2022
Consejo Nacional de Ciencia y Tecnología
2021
Instituto de Cancerología Las Américas
2018
Universidad Nacional de Colombia
2015-2017
Biomedical Research Networking Center on Neurodegenerative Diseases
2014
Universitat de València
2014
Parc Científic de la Universitat de València
2013
Centro de Investigación Biomédica en Red
2013
The number of elderly people is projected to double in the next 50 years worldwide, resulting an increased prevalence neurodegenerative diseases. Aging causes changes brain tissue homeostasis, thus contributing development disorders. Current treatments are not entirely effective, so alternative or adjuvant agents being actively sought. Antioxidant properties phenolic compounds particular interest for diseases whose psychopathological mechanisms strongly rely on oxidative stress at level....
The "glutamatergic" granule cells of the dentate gyrus transiently express a GABAergic phenotype when state hyperexcitability is induced in adult rat. Consequently, cell (GC) activation provokes monosynaptic responses their targets area CA3. Because GABA exerts trophic action on neonatal CA3 and mossy fibers (MF) constitute its main input, we hypothesized that MF could also be expressed early life. We addressed this possibility with multidisciplinary approach. Electrophysiological recordings...
Environmental, genetic and epigenetic risk factors have been closely related to the development of type-2 diabetes (T2D). It has reported that expression in H19 MALAT1 are metabolic diseases. To analyze relationship between lncRNAs with diabetic patients. A study was conducted subjects T2D nondiabetic controls, residents Mexico City. Anthropometric measurements were made, serum concentrations glucose, glycosylated hemoglobin, total cholesterol, triglycerides, high- low-density lipoprotein...
The phytochemical compositions of green coffee beans (GB), roasted (RC), and the solid residue known as spent grounds (SCG) have been associated with beneficial physiological effects. objective this study was to analyze total phenolic compounds, antiradical scavenging ability, antibacterial activity, antiproliferative activity on cancer cells aqueous ethanolic extracts GB, RC, SCG samples. content quantified by Folin–Ciocalteu assay, while evaluated ABTS●+ DPPH radical assays, determined...
Background Exosomes are microvesicles that actively participate in signaling mechanisms and depending on their content can contribute to the development of different pathologies, such as diabetes cardiovascular disease. Objective The aim this study was evaluate association cystatin C, CD26, CD14 proteins serum exosomes from patients with Type 2 Diabetes (T2D), metabolic syndrome (MetS), atherogenic index plasma (AIP). Methods Serum were isolated by ultracentrifugation 147 individuals without...
Water activity (aw) influences the growth of fungi as well biosynthesis ochratoxin A (OTA). The objective this study was to obtain critical storage conditions at which coffee beans are not susceptible deteriorative physical changes and quantification OTA in dry cherries green-coffee after 60 days 35°C. aw significantly affected color, texture, morphology storing. Three different genera were isolated from samples, Aspergillus, Rhizopus, Penicillium. analyzed showed a high concentration...
Helicobacter pylori promotes the secretion of cytokines that regulate inflammation and carcinogenesis. Immune cells secrete into extracellular medium or packaged in exosomes. The objective this study was to analyze profile soluble exosomal were secreted by human peripheral blood mononuclear (PBMCs) infected with H. build a network interaction between cellular proteins. PBMCs obtained density gradient centrifugation for 24 h. infection verified immunofluorescence Western blot CagA. exosomes...
Breast cancer is the most common invasive neoplasm and leading cause of death in women worldwide. The main mortality patients invasion metastasis, where epithelial-mesenchymal transition (EMT) a crucial player these processes. Pharmacological therapy has plants as its primary source, including isoflavonoids. Brazilin an isoflavonoid isolated from
The enzymes of the family peptidylarginine deiminases (PADs) have an important role in pathogenesis rheumatoid arthritis (RA) due to their association with anti-citrullinated protein antibodies (ACPA) production. To evaluate between single-nucleotide polymorphisms (SNPs) PADI2 gene and RA susceptibility, related clinical parameters, serologic status autoantibodies a women population from southern Mexico, case-control study was conducted (case n=229; control n=333). Sociodemographic...