A5051815430- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Global Cancer Incidence and Screening
- Esophageal and GI Pathology
- Global Public Health Policies and Epidemiology
- Microscopic Colitis
- Healthcare Systems and Reforms
- Inflammatory Bowel Disease
- Celiac Disease Research and Management
- Diverticular Disease and Complications
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- COVID-19 Clinical Research Studies
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Gastrointestinal motility and disorders
- Neuroendocrine Tumor Research Advances
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Bleeding Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Gastrointestinal Tumor Research and Treatment
University of Alabama at Birmingham
2021-2025
Office of Minority Health and Health Equity
2024
National Autonomous University of Honduras
2021-2024
University of Alabama at Birmingham Hospital
2024
RELX Group (Netherlands)
2024
Western Regional Hospital
2020-2024
Universidad Metropolitana de Honduras
2020-2024
Indiana University
2023
Honduras Foundation for Agricultural Research
2019-2020
Abstract Background: Two-thirds of global cancers occur in low/middle income countries (LMIC). Northern Central America is the largest LMIC region Western Hemisphere and lack cancer registries to guide control. We conducted a gastric survival study rural Honduras, characterized as having among highest incidence rates Latin America. Methods: The cohort incident diagnosed between 2002 2015 was studied with active follow-up household visits. regional registry primary for case identification,...
Abstract Background: Gastric adenocarcinoma is the fourth leading cause of global cancer mortality and infection-associated cancer. has significant geographic variability, with a high incidence in East Asia mountainous regions Latin America. In United States, gastric represents marked disparity rates that are two to three times higher Hispanics compared non-Hispanic Whites. Methods: We conducted national retrospective study incident El Salvador from 2000 2014 estimate age-standardized rate...
Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused substantial morbidity and mortality worldwide. Few reports exist in Latin America, a current epicenter of transmission. Here, we aim to describe the epidemiology outcomes associated with disease 2019 (COVID-19) Honduras. Methods Baseline clinical epidemiological information SARS-CoV-2 reverse transcriptase polymerase chain reaction–confirmed cases detected between 17 March–4 May San Pedro...
Abstract Biomass cookstove food preparation is linked to aero-digestive cancers, mediated by ingested and inhaled carcinogens (e.g., heterocyclic amines, polycyclic aromatic hydrocarbons). We investigated the association between gastric adenocarcinoma, wood use, H. pylori CagA infection risk modification variants in genes that metabolize affect internal dose of carcinogens. conducted a population-based, case–control study (814 incident cases, 1049 controls) rural Honduras, high-incidence...
PURPOSE Population-based cancer registries (PBCRs) are critical for national control planning, yet few low- and middle-income countries (LMICs) have quality PBCRs. The Central America Four region represents the principal LMIC in Western hemisphere. We describe establishment of a PBCR rural Honduras with first estimates 2013-2017 period. METHODS was established through collaboration academic institutions Ministry Health collection incident data from public private health services. Data were...
Abstract Background: Gastric adenocarcinoma is the fourth leading cause of cancer-related mortality and infection-associated cancer. has striking geographic variability, with high incidence in East Asia mountainous Latin America. Reliable cancer data population-based registries are lacking for majority low- middle-income countries, including Central American Four region (CA-4, Nicaragua, El Salvador, Honduras, Guatemala). Methods: Mortality Nicaragua were obtained from highly rated Ministry...
Cardiovascular Disease (CVD) epidemiology varies significantly among Low and Middle-Income Countries. Honduras is the Central American country with highest Ischemic Heart CVD mortality rates. The aim of this study was to assess individual risk factors calculate Risk Assessment Scores (CVRAS) from population. Methods: A cross-sectional in western Honduras. Estimation CV performed using Framingham, MESA, ACC/AHA-PCEs ESC SCORE calculators. Results: 38% were male. For men women respectively;...
INTRODUCTION: The prevalence of the Functional Gastrointestinal Disorders (FGIDs) in Latino populations resource-limited settings such as rural Central America is largely uninvestigated. relationship FGIDs and dietary habits unknown this environment. METHODS: With population-based sampling, we administered Rome IV questionnaire a validated to cross-section general adult population Western Honduras. We estimated specific used logistic regression with Bonferroni adjustment evaluate each FGID...
We report a case of an 81-year-old male immigrant from Latin American developing country with high burden upper gastrointestinal neoplasms, who presented small bowel stromal tumor (GIST) after 2 years delay in the diagnosis due to multiple barriers healthcare. The patient partial intestinal obstruction abdominal computed tomography (CT) scan suggestive GIST. Surgical resection was performed, and adjuvant therapy initiated imatinib (a tyrosine kinase inhibitor) confirmed. had successful...
PURPOSE: Dexamethasone has become the standard of care for treating patients with coronavirus disease 2019 (COVID-19) who require oxygen.This therapeutic regiment been found to decrease mortality in COVID-19.The RECOVERY trial proposed utilizing dexamethasone at 6 mg daily, but some feel this dose is not high enough ameliorate cytokine storm patients.Studies like DEXA-ARDS have utilized higher doses (20 IV daily) accelerated from ventilator and more free days.Despite increasing evidence...
BackgroundThe COVID-19 pandemic has had a severe impact on the Latin American subcontinent, particularly in areas with limited hospital resources and restricted Intensive Care Unit (ICU) capacity. This study aimed to provide comprehensive description of clinical characteristics, outcomes, factors associated survival hospitalized patients Honduras.Research questionWhat were characteristics outcomes large referral center Honduras?Study design methodsThis employed retrospective cohort conducted...
The significant global burden of colorectal cancer accentuates disparities in access to preventive healthcare most low- and middle-income countries (LMICs) as well large sections underserved populations within high-income countries. barriers screening economically transitioning Latin America are multiple. At the same time, immigration from these USA continues increase. This case highlights delays diagnosis experienced by a recent immigrant country with no established program, an population...