A5101833826- Nanoplatforms for cancer theranostics
- Immune cells in cancer
- Nanoparticle-Based Drug Delivery
- Extracellular vesicles in disease
- Dendrimers and Hyperbranched Polymers
- Photodynamic Therapy Research Studies
- RNA Interference and Gene Delivery
- Wound Healing and Treatments
- Advanced Photocatalysis Techniques
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Analytical chemistry methods development
- Advanced Battery Technologies Research
- Advancements in Transdermal Drug Delivery
- Advanced Sensor and Energy Harvesting Materials
- Neuroinflammation and Neurodegeneration Mechanisms
- Lung Cancer Research Studies
- Advanced Battery Materials and Technologies
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Polymer Surface Interaction Studies
- Immunotherapy and Immune Responses
- Advancements in Battery Materials
- Hydrogels: synthesis, properties, applications
Sun Yat-sen University
2019-2025
Xuzhou Medical College
2022-2025
Nanyang Technological University
2023-2024
Gansu University of Traditional Chinese Medicine
2024
The Seventh Affiliated Hospital of Sun Yat-sen University
2023
Beijing University of Civil Engineering and Architecture
2023
The First Affiliated Hospital, Sun Yat-sen University
2021
Shanghai Jiao Tong University
2020
Harbin Institute of Technology
2015
As a mussel-inspired material, polydopamine (PDA), possesses many properties, such as simple preparation process, good biocompatibility, strong adhesive property, easy functionalization, outstanding photothermal conversion efficiency, and quenching effect. PDA has attracted increasingly considerable attention because it provides versatile approach to functionalize material surfaces for obtaining variety of multifunctional nanomaterials. In this review, recent significant research...
The treatment of diabetic wounds faces enormous challenges due to complex wound environments, such as infected biofilms, excessive inflammation, and impaired angiogenesis. critical role the microenvironment in chronic has not been addressed for therapeutic development. Herein, we develop a microneedle (MN) bandage functionalized with dopamine-coated hybrid nanoparticles containing selenium chlorin e6 (SeC@PA), which is capable dual-directional regulation reactive species (RS) generation,...
Abstract The therapeutic application of STING agonists in various malignancies has been limited by factors such as the inability systemic administration and immunosuppressive tumor microenvironment. Herein, this work reports a mesoporous polydopamine‐based multifunctional nanoplatform loaded with agonist MSA‐2 chelated Mn 2+ for synergistic photothermal activation‐based immunotherapy. effectively delivers to site intelligently releases its contents through acid degradation, facilitated...
Abstract A Z‐scheme heterojunction with high electron–hole pairs separation efficacy and enhanced redox potentials exhibits tremendous potential in photonic theranostics, but still remains unexplored challenging. Herein, novel 2D thermally oxidized pyrite nanosheets (TOPY NSs) FeS 2 core Fe O 3 shell are fabricated combining ball grinding two‐step probe sonication assisted liquid exfoliation under different solution air environments. The 3+ /Fe 2+ inside TOPY NSs can both damage the tumor...
Complex composition and abnormal growth state of cells tissues in the solid tumor microenvironment often lead to high density stiffness different from normal tissues, thus forming a physical barrier prevent penetration nanomedicines. Charge-reversal nanomedicines are kind emerging smart nano-systems that can show change surface charge negative positive before after reaching site, effectively enhancing by promoting transcytosis, while maintaining vivo safety. In this review, we provide...
As a promising 2D nanocarrier, the biggest challenge of bare black phosphorus nanosheets (BP NSs) lies in inherent instability, while it can be improved by surface modification strategies to great extent. Considering existing infirm BP NSs strategies, A mussels-inspired strong adhesive biomimetic peptide with azide groups for increase stability is synthesized. The on quickly and precisely bind targeting ligand through click chemistry, solving problem nonspecificity secondary other...
Photothermal therapy (PTT) applies photothermal agents to convert light into heat eliminate primary tumors and induce subsequent immune responses, but the ineffectiveness in metastatic or recurrent hinders its further use. Based on adaptive immunity, immunotherapy can suppress tumor growth, immunosuppressive microenvironment limits therapeutic effect. Excellent synergistic effects distant have been found many studies combining two therapies. In this review, principles, materials, latest...
Despite growing prevalence and incidence, the management of gout remains suboptimal. The intermittent nature makes long-term urate-lowering therapy (ULT) particularly important for management. However, patients are reluctant to take medication day after manage incurable occasional flares, suffer from possible toxicity. Therefore, a safe easy-to-operate drug delivery system with simple preparation is very necessary. Here, chitosan-containing sustained-release microneedle co-loaded colchicine...
Constructing hierarchical superstructures to achieve comparable complexity and functions proteins with four-level hierarchy is challenging, which relies on the elaboration of novel building blocks complex structures. We present a series catenated cages unique structural tailorability. The rational design was realized as such: A catenane two symmetric (CSC), CSC-1, all rigid imine panels converted dissymmetric (CDC), CDC-1, exterior flexible amine panels, CDC-5 tailored from CDC-1 by...
Abstract The treatment of chronic wounds still presents great challenges due to being infected by biofilms and the damaged healing process. current treatments do not address needs wounds. In this study, a highly effective dressing (Dox‐DFO@MN Hy) for is described. This combines advantages microneedles (MNs) hydrogels in MNs employed debride break down wound barrier, providing rapid access therapeutic drugs from hydrogel backing layer. Importantly, kill pathogenic bacteria specifically,...
Bufalin is a promising active ingredient in traditional Chinese medicine but has shown limited anticancer applications due to its toxicity. Here, we report BCNPs@gel, bufalin-containing CaCO
The poor safety performance of high energy density lithium ion batteries (LIBs) is drawing increasing public concern. To enhance the on battery level, it indispensable to design safe electrolytes that are both non‐flammable and low exothermic under abusive conditions. By rational design, a localize concentration electrolyte (LHCE) with non‐flammability extremely exothermicity formulated. Compared conventional LiPF6‐organocabonate previous LHCEs, heat generated by reaction between LHCE fully...
The poor safety performance of high energy density lithium ion batteries (LIBs) is drawing increasing public concern. To enhance the on battery level, it indispensable to design safe electrolytes that are both non‐flammable and low exothermic under abusive conditions. By rational design, a localize concentration electrolyte (LHCE) with non‐flammability extremely exothermicity formulated. Compared conventional LiPF6‐organocabonate previous LHCEs, heat generated by reaction between LHCE fully...