A5100703876- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Wound Healing and Treatments
- Cardiovascular Disease and Adiposity
- Advancements in Transdermal Drug Delivery
- Dermatology and Skin Diseases
- Cardiac pacing and defibrillation studies
- Biomarkers in Disease Mechanisms
- Meningioma and schwannoma management
- Obstructive Sleep Apnea Research
- Immunotherapy and Immune Responses
- Coronary Interventions and Diagnostics
- Foreign Body Medical Cases
- Aortic Disease and Treatment Approaches
- Spectroscopy and Chemometric Analyses
- Elasticity and Material Modeling
- Heart Failure Treatment and Management
- Blood Coagulation and Thrombosis Mechanisms
- Pericarditis and Cardiac Tamponade
- IgG4-Related and Inflammatory Diseases
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular and exercise physiology
- Inflammatory Biomarkers in Disease Prognosis
Nanjing Tech University
2025
Center for Experimental and Clinical Infection Research
2025
Medizinische Hochschule Hannover
2025
Radboud University Nijmegen
2025
Radboud University Medical Center
2025
Centre for Individualised Infection Medicine
2025
Helmholtz Centre for Infection Research
2025
Sun Yat-sen University
1997-2023
Tianjin Chest Hospital
2019-2021
Southeast University
2021
Abstract The treatment of chronic wounds still presents great challenges due to being infected by biofilms and the damaged healing process. current treatments do not address needs wounds. In this study, a highly effective dressing (Dox‐DFO@MN Hy) for is described. This combines advantages microneedles (MNs) hydrogels in MNs employed debride break down wound barrier, providing rapid access therapeutic drugs from hydrogel backing layer. Importantly, kill pathogenic bacteria specifically,...
Most existing vaccines, delivered by intramuscular injection (IM), are typically associated with stringent storage requirements under cold-chain distribution and professional administration medical personnel often result in the induction of weak mucosal immunity. In this context, we reported a microneedle (MN) patch to deliver chitosan oligosaccharide (COS)-encapsulated DNA vaccines (DNA@COS) encoding spike nucleocapsid proteins SARS-CoV-2 as vaccination technology. Compared IM immunization,...
Abstract No-reflow is an important complication among patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). A retrospective study of 1658 STEMI direct PCI was performed. Patients were randomly assigned at a 7:3 ratio into development cohort and validation no-reflow normal blood flow groups. Clinical data laboratory examinations compared to identify independent risk factors establish scoring system. In the (n = 1122), 331...
Abstract Background Sarcoidosis is a disease of unknown etiology characterized by the formation immune cell accumulation (granuloma) in lung and other tissues. Chronic sarcoidosis may lead to pulmonary fibrosis. Aim To unravel cellular niches within granuloma chronic patients using spatial transcriptomics. Methods Spatial transcriptomics Visium platform (10x Genomics) was performed on nine granuloma-containing explants from patients. Validation gene expression through immunohistofluorescence...
ABSTRACT Deep-sea cold seeps harbor unique microbial communities that play crucial roles in biogeochemical cycles and possess potential biotechnological applications. Herein, we report the isolation, characterization, genomic analysis of a novel Bacillus species, haimaensis sp. nov. (type strain CSS-39 T , CCTCC M20241382), obtained from sediments collected at depth 1,350 m Haima seep, South China Sea. Phylogenomic analysis, revealing an average nucleotide identity 87.78% digital DNA-DNA...
Objective Insufficient myocardial reperfusion for patients with acute infarction (AMI) during primary percutaneous coronary intervention (PPCI) has a great influence on prognosis. The aim of this study was to investigate the association platelet-to-lymphocyte ratio (PLR) and in-hospital major adverse cardiac events (MACEs) in AMI undergoing PPCI. Design Retrospective cohort study. Setting Patients researchers from two tertiary hospitals. Participants A total 445 consecutive who underwent...
Bicuspid aortic valve (BAV) is common congenital malformation, bicuspid stenosis accounts for a substantial proportion of patients with (AS). AS are more likely to have dilatation slightly less elliptical annuli, which might lead paravalvular regurgitation (AR) and permanent pacemaker implantation (PPM) after TAVI higher mortality. Our study aims understand the therapeutic efficacy safety transcatheter (TAVI) supra-annular structure-based sizing strategy in Chinese BAV versus tricuspid...
The purpose of this study was to screen the predictive factors no-reflow after a percutaneous coronary intervention (PCI) in elderly patients with ST-segment elevation myocardial infarction (STEMI), and construct nomogram model, guide clinical treatment.A total 551 STEMI (age >65) underwent direct PCI were randomly classified into training group (n=386, 70%) validation (n=165, 30%). All two groups divided normal blood flow according whether there phenomenon. Univariable multivariable...
In the field of biomedicine, time irreversibility is used to describe how imbalanced and asymmetric biological signals are. As an important feature signals, direction always ignored. To find out variation regularity heart rate variability (HRV) in initial stage hypoxic exposure, present study implemented 2 h acute normobaric exposure on six young subjects who have no plateau or hypoxia experiences; oxygen concentration was set as 12.9%. Electrocardiogram (ECG) were recorded whole process RR...
Background Postsystolic shortening (PSS) has been proposed as a marker of myocardial dysfunction. Strain rate imaging (SRI) is novel ultrasonic technique, allowing reliable and noninvasive measurement deformation. The purpose this study was to investigate the characteristics longitudinal PSS by SRI in ischemic infarct myocardium patients with coronary artery disease, explore its clinical applicability. Methods Eleven angina pectoris, 21 infarction 20 healthy subjects were included study....
An 11-year-old boy was referred for unexplained fever of 3 months. Laboratory tests showed elevated white blood cell count with a left shift, and decreased haemoglobin level. Blood cultures at admission were negative. Chest radiograph displayed no abnormal findings. The illness responded poorly to antibiotics. Echocardiography revealed moderate-sized, highly …
Use MATLAB Image Processing Toolbox to extract eight typical characteristics from leaves, i.e., circumference, roundness, complexity, extension, sphericity, mean variation coefficient and saw-teeth degree. Then, using three kinds of classifier such as BP network, PNN SVM recognize the 400 samples recognition rate can be reached 87.22%, 88.95%, 95.15%, respectively. Furthermore, B&B algorithm is employed select these characteristic sets remove their redundancy, thus, processed are sent...
Abstract Background To investigate changes of tissue factor (TF) and pathway inhibitor (TFPI) in the acute phase cardiogenic stroke patients with atrial fibrillation (AF). Methods A total 152 nonvalvular persistent AF, 103 126 cases noncardiogenic were enrolled. Non-AF (n = 138) without served as controls. The clinical data, biochemical indicators, plasma levels von Willebrand (vWF), TF, TFPI determined. Results Compared controls, vWF TF significantly higher, while TFPI/TF ratio lower (all P...