A5102945095- Sarcoma Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Bone Tumor Diagnosis and Treatments
- Colorectal Cancer Treatments and Studies
- Musculoskeletal synovial abnormalities and treatments
- Gastric Cancer Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Adrenal and Paraganglionic Tumors
- MRI in cancer diagnosis
- Attention Deficit Hyperactivity Disorder
- Cardiac tumors and thrombi
- Bone health and osteoporosis research
- Cardiovascular Disease and Adiposity
- Tumors and Oncological Cases
- Chemokine receptors and signaling
- Bipolar Disorder and Treatment
- Bone and Joint Diseases
- Bone Metabolism and Diseases
- Aortic Thrombus and Embolism
- Connective tissue disorders research
- Tuberculosis Research and Epidemiology
- Virus-based gene therapy research
- Cardiovascular Health and Risk Factors
Hebei Food Inspection and Research Institute
2025
Soochow University
2012-2023
First Affiliated Hospital of Soochow University
2012-2023
Central South University
2021
Tianjin Chest Hospital
2014-2020
Shanghai Jiao Tong University
2009-2018
Shanghai Ninth People's Hospital
2018
Shanghai Sixth People's Hospital
2018
Tianjin Medical University
2017
Shandong First Medical University
2015
Abstract The delicate balance between bone formation by osteoblasts and resorption osteoclasts maintains homeostasis. Nuclear receptors (NRs) are now understood to be crucial in physiology pathology. However, the function of Farnesoid X receptor (FXR), a member NR family, regulating homeostasis remains incompletely understood. In this study, vitro vivo models revealed delayed development an osteoporosis phenotype mice lacking FXR marrow mesenchymal stem cells (BMSCs) due impaired osteoblast...
We investigated the diagnostic values of microRNA-31 in peripheral blood mononuclear cells (PBMCs) for pediatric pulmonary tuberculosis Chinese patients.Sixty-five children with TB were selected this study, which was conducted at Department Infectious Diseases People's Hospital Laiwu City between December 2013 and 2014.Sixty healthy children, parallel, served as control group.Real-time PCR used to detect miR-31 expression PBMCs.Serum levels IL-6, TNF-α, NF-κB, IFN-γ detected by ELISA.ROC...
Objectives Researchers continue to seek easier ways evaluate the quality of bone and screen for osteoporosis osteopenia. Until recently, radiographic images various parts body, except distal femur, have been reappraised in light dual-energy X-ray absorptiometry (DXA) findings. The incidence osteoporotic fractures around knee joint elderly continues increase. aim this study was propose two new parameters femur assessment quality. Methods Anteroposterior radiographs mineral density (BMD)...
Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide. MicroRNAs (MiRNAs) have been reported to regulate functions through exosomes. Through the Gene Expression Omnibus (GEO) database, miR-620 was selected as serum miRNA highly expressed in ESCC, but its detailed role ESCC has not explored. Tumor-secreted miRNAs promote metastasis reprogramming aerobic glycolysis lung fibroblasts. Therefore, we intended verify whether exosomal secreted cells may...
Bicuspid aortic valve (BAV) is common congenital malformation, bicuspid stenosis accounts for a substantial proportion of patients with (AS). AS are more likely to have dilatation slightly less elliptical annuli, which might lead paravalvular regurgitation (AR) and permanent pacemaker implantation (PPM) after TAVI higher mortality. Our study aims understand the therapeutic efficacy safety transcatheter (TAVI) supra-annular structure-based sizing strategy in Chinese BAV versus tricuspid...
Abstract: Mammary analog secretory carcinoma (MASC) of salivary gland is a recently described neoplasm that morphologically and immunohistochemically resembles the breast. Genetically, both them harbor ETV-6-NTRK-3 fusion rearrangement. One case primary MASCs arising from eyelid reported. The patient was 52-year-old man. Microscopically, tumor exhibited nodular aggregation solid, tubular, microcystic/macrocystic structures. Characteristic “colloid-like” eosinophilic material present within...
Objective To investigate the feasibility and diagnostic value of a preoperative transthoracic echocardiography‐guided three‐dimensional printed model ( TTE ‐guided 3 DPM ) for assessment structural heart disease SHD ). Methods Fourty‐four patients underwent cardiac surgery at Tianjin Chest Hospital. The were preoperatively assessed using , which was compared to conventional echocardiography (3D along with direct intraoperative findings, considered “gold standard.” Twelve had including four...
To investigate the relationship between lipoprotein(a) gene (LPA) polymorphisms and calcific aortic valve disease (CAVD) coronary heart (CHD) in Han Chinese.A total of 148 patients were recruited (n = 71 with CAVD n 77 CHD) based on a diagnosis achieved using color Doppler echocardiography, angiography, or computed tomography angiography. Seventy-one control individuals without CHD also recruited. Biomarkers including levels [Lp(a)], low-density lipoprotein high-density cholesterol,...
Aim To study the changes of mitral valve ( MV ) in patients with nonvalvular atrial fibrillation NVAF )‐related regurgitation MR and relationship between parameters enlarged left atrium LA ). Materials Methods A total 43 were divided into two groups: (1) 1 group mild (2) 2 moderate‐to‐severe . Real time 3D transesophageal echocardiography TEE was performed to detect structure Results There no significant differences basic characteristics among three groups. As compared control group,...
The study aimed to investigate the role of low-dose dobutamine stress myocardial contrast echocardiography (MCE) in evaluating local microcirculation and predicting cardiac function recovery patients with infarction. A total 50 acute infarction (AMI) were enrolled present study. Positron emission tomography was used as a gold standard determine viable/non-viable segments infarcted region. MCE carried out 72 h after PCI. again evaluate condition at 6 months As compared normal segments,...
Human embryonic germ cells (hEGCs) are stem cultured from primordial cells, which reside in human genital ridges vivo. In this study, hEGCs were induced to differentiate into cardiomyocytes by treatment with ascorbic acid vitro and the effects of hEGC transplantation on rat models acute myocardial infarction (AMI) investigated. incubated differentiation medium containing at various concentrations. Levels GATA-4 expression measured identify optimal concentration inductor. Immunofluorescence...