A5101645446- Acupuncture Treatment Research Studies
- RNA modifications and cancer
- Cardiac Valve Diseases and Treatments
- Healthcare and Venom Research
- Cardiac Imaging and Diagnostics
- Cancer-related molecular mechanisms research
- Traditional Chinese Medicine Studies
- Complementary and Alternative Medicine Studies
- Disaster Response and Management
- Medical Research and Treatments
- Structural Engineering and Vibration Analysis
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Migraine and Headache Studies
- Blockchain Technology Applications and Security
- Pancreatic and Hepatic Oncology Research
- Digital Media and Visual Art
- Cellular Mechanics and Interactions
- Cardiovascular Function and Risk Factors
- Cancer Research and Treatments
- Research studies in Vietnam
- Phenomenology and Existential Philosophy
- Medical and Agricultural Research Studies
- Technology and Security Systems
Zhongshan Hospital of Xiamen University
2023-2025
Fudan University
2024-2025
Tianjin Nankai Hospital
2024-2025
Tianjin Medical University
2024-2025
Zhongshan Hospital
2024-2025
Instituto Medicina Integrativa (Portugal)
2024
Shanghai Tenth People's Hospital
2024
Tongji University
2024
Lanzhou University Second Hospital
2024
Lanzhou University
2024
BACKGROUND: Aortic dissection (AD) is a fatal cardiovascular disorder without effective medications due to unclear pathogenic mechanisms. Bestrophin3 (Best3), the predominant isoform of bestrophin family in vessels, has emerged as critical for vascular pathological processes. However, contribution Best3 diseases remains elusive. METHODS: Smooth muscle cell–specific and endothelial knockout mice (Best3 SMKO ECKO , respectively) were engineered investigate role pathophysiology. Functional...
Abstract The abnormal tumor mechanical microenvironment due to specific cancer‐associated fibroblasts (CAFs) subset and low immunogenicity caused by inefficient conversion of active chemotherapeutic agents are two key obstacles that impede patients with desmoplastic tumors from achieving stable complete immune responses. Herein, it is demonstrated FAP‐α + CAFs‐induced stromal stiffness accelerated progression precluding cytotoxic T lymphocytes. Subsequently, a cascade‐responsive nanoprodrug...
Rice is the staple food for approximately half global population, and rice virus diseases pose a serious threat to production, leading significant losses in yield quality, endangering agricultural security. Over past two decades, advancements have been made by Chinese scientists plant virology, encompassing basic research development of control measures viral (Wu et al., 2022, 2023). Since initial identification 1895, more than twenty viruses reported impair yields. Notably, both RRSV RGSV...
Adjuvant acupuncture for the symptomatic treatment of migraine reduces frequency headaches and may be at least similarly effective to with prophylactic drugs.This article describes an open-label randomized controlled clinical trial two groups: intervention group (n=42) waiting-list control (n=44). This study occurred Czech-Chinese Center Traditional Chinese Medicine University Hospital Hradec Kralove between October 2015 April 2017.After 12 weeks acupuncture, number days was reduced by 5.5...
Abstract Background Neoadjuvant immunochemotherapy (NICT) plus esophagectomy has emerged as a promising treatment option for locally advanced esophageal squamous cell carcinoma (LA-ESCC). Pathologic complete response (pCR) is key indicator associated with great efficacy and overall survival (OS). However, there are insufficient indicators the reliable assessment of pCR. Methods 192 patients LA-ESCC treated NICT from December 2019 to October 2023 were recruited. According pCR status,...
The unique physical tumor microenvironment (TME) and aberrant immune metabolic status are two obstacles that must be overcome in cancer immunotherapy to improve clinical outcomes. Here, an situ mechano-immunometabolic therapy involving the injection of a biomimetic hydrogel is presented with sequential release anti-fibrotic agent pirfenidone, which softens stiff extracellular matrix, small interfering RNA IDO1, disrupts kynurenine-mediated immunosuppressive pathways, together multi-kinase...
To investigate the possible association between plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) and incidence severity of calcific aortic valve disease (CAVD).This prospective, cross sectional study involved patients with without (controls) calcification diagnosed by transthoracic echocardiography dual source computed tomography (DSCT) scan. Aortic valves scores were calculated from DSCT scans graded: grade 1, no calcification; 2, mildly calcified; 3, moderately 4, heavily...
Huangqi Guizhi Wuwu Decoction(HQGZWWD) is a Traditional Chinese Medicine formula from Synopsis of Golden Chamber used to treat blood arthralgia. According the principle that same treatment can be for different diseases, HQGZWWD has proven effective IgA nephropathy (IgAN) associated with spleen and kidney yang deficiency.
Objective To investigate the feasibility and diagnostic value of a preoperative transthoracic echocardiography‐guided three‐dimensional printed model ( TTE ‐guided 3 DPM ) for assessment structural heart disease SHD ). Methods Fourty‐four patients underwent cardiac surgery at Tianjin Chest Hospital. The were preoperatively assessed using , which was compared to conventional echocardiography (3D along with direct intraoperative findings, considered “gold standard.” Twelve had including four...
Percutaneous coronary intervention (PCI) is the recommended treatment for high risk patients with non-ST-segment elevation myocardial infarction (NSTEMI).To investigate application of three dimensional-speckle tracking imaging (3D-STI) on diagnosed NSTEMI undergoing PCI.Forty-four and 20 healthy subjects that received basic clinical laboratory examinations were included in our study. divided into groups: heart failure (HF) normal ejection fraction (HF-NEF group, n = 19), preserved (HF-PEF...
Aim To study the changes of mitral valve ( MV ) in patients with nonvalvular atrial fibrillation NVAF )‐related regurgitation MR and relationship between parameters enlarged left atrium LA ). Materials Methods A total 43 were divided into two groups: (1) 1 group mild (2) 2 moderate‐to‐severe . Real time 3D transesophageal echocardiography TEE was performed to detect structure Results There no significant differences basic characteristics among three groups. As compared control group,...
Background: Acupuncture has become a viable option for migraine prophylaxis in Europe; however, despite its wide use, more data on the short- and long-term cost-effectiveness are needed when considering perspectives of paying third-party, patient, society general. The aim was to evaluate cost effectiveness adjuvant acupuncture pharmacologic treatment vs alone patients after 3-month course 6-month follow-up from all perspectives. Methods: study involved an open-label randomized clinical trial...
The study aimed to investigate the role of low-dose dobutamine stress myocardial contrast echocardiography (MCE) in evaluating local microcirculation and predicting cardiac function recovery patients with infarction. A total 50 acute infarction (AMI) were enrolled present study. Positron emission tomography was used as a gold standard determine viable/non-viable segments infarcted region. MCE carried out 72 h after PCI. again evaluate condition at 6 months As compared normal segments,...
To evaluate the efficacy, safety, and economics of mecapegfilgrastim recombinant human granulocyte colony-stimulating factor (rhG-CSF) in primary prevention chemotherapy-related neutropenia non-small cell lung cancer (NSCLC).