A5037675875- Acupuncture Treatment Research Studies
- Gastrointestinal motility and disorders
- Inflammatory Bowel Disease
- Music Therapy and Health
- Pharmacological Effects of Natural Compounds
- Complementary and Alternative Medicine Studies
- Healthcare and Venom Research
- Barrier Structure and Function Studies
- Autoimmune and Inflammatory Disorders Research
- Ovarian function and disorders
- Reproductive Biology and Fertility
- Autophagy in Disease and Therapy
- Traditional Chinese Medicine Studies
- Heme Oxygenase-1 and Carbon Monoxide
- RNA Research and Splicing
- Pediatric Pain Management Techniques
- Cancer Cells and Metastasis
- Pain Mechanisms and Treatments
- Cancer-related molecular mechanisms research
- Infant Health and Development
- Lipid metabolism and disorders
- Dermatology and Skin Diseases
- Sexual function and dysfunction studies
- Force Microscopy Techniques and Applications
- Antioxidants, Aging, Portulaca oleracea
Yueyang Hospital
2013-2024
Shanghai University of Traditional Chinese Medicine
2014-2024
Shanghai Research Center for Acupuncture and Meridians
2016-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2017
Creative Research Enterprises (United States)
2017
Shanghai University
2013-2016
Sir Run Run Shaw Hospital
2010-2014
Zhejiang University
2010-2014
Tongde Hospital of Zhejiang Province
2014
Affiliated Hospital of Hebei University
2014
Hyperandrogenism is a core factor in the series of reproductive and endocrine metabolic disorders involved polycystic ovary syndrome (PCOS). Abnormalities enzymatic activity expression ovarian granular cell layer P450arom theca P450c17α can lead to an atypical environment local hormones, including excessive androgen levels. Rat models prepared with letrozole exhibit similar histological changes those that occur human PCOS. We used such model study role electro-acupuncture (EA) regulating...
Abstract Background Small intestinal bacterial overgrowth ( SIBO ) may be a cause of irritable bowel syndrome IBS ); however, current investigations have important limitations. We aimed to identify clinically relevant diagnostic criteria for based on lactulose hydrogen breath test LHBT alone and combined with scintigraphic measurement oro‐cecal transit SOCT ). Methods Results / investigation from 89 patients 13 healthy volunteers were included in systematic analysis six published diagnosis....
Abnormal pain processing in the central nervous system may be related to abdominal patients with Crohn's disease (CD). The purpose of this study was investigate changes resting-state brain activity CD remission and its relationship presence pain. Twenty-five pain, 25 without 32 healthy subjects were scanned using a 3.0-T functional magnetic resonance imaging scanner. Regional homogeneity (ReHo) used assess activity. Daily scores collected 1 week before imaging. We found that exhibited lower...
Many studies report a high prevalence of lactose intolerance in patients with functional, gastrointestinal disease.To evaluate the role small intestinal bacterial overgrowth (SIBO) condition and mechanism by which SIBO may impact tolerance affected patients.Consecutive out-patients chronic functional diarrhoea (CFD) healthy controls underwent validated 20 g hydrogen breath test (HBT). Patients completed also 10 lactulose HBT concurrent assessment bowel transit scintigraphy.Lactose...
Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and follicular arrest. These two characteristics may result from an imbalance between anti-Müllerian hormone follicle stimulating hormone. Electroacupuncture effective in improving arrest PCOS; however, the mechanism not sufficiently clear. This study aimed to elucidate whether electroacupuncture PCOS exerted regulating of In this study, a rat model polycystic was treated with low-frequency at acupoints (CV-3 CV-4). To...
To compare the impacts of electroacupuncture (EA) and moxibustion (Mox) on primary gastrointestinal symptoms expressions colonic mucosa-associated neuropeptide substance P (SP) vasoactive intestinal peptide (VIP) in patients with either diarrhea-predominant or constipation-predominant irritable bowel syndrome (IBS-D IBS-C, respectively). Eighty-five IBS were randomly allocated to EA Mox groups. Zusanli (ST 36) Shangjuxu 37) selected as acupoints for warm treatment once a day 14 consecutive...
Objective. To compare the impacts of electroacupuncture (EA) and mild moxibustion (Mox) on patients with irritable bowel syndrome (IBS). Method. Eighty-two IBS were randomly allocated into EA group (n = 41) Mox received corresponding interventions for four weeks. Before after treatment, Visual Analogue Scale Irritable Bowel Syndrome (VAS-IBS) was used to evaluate gastrointestinal symptoms mental well-being; expression serotonin (5-hydroxytryptamine, 5-HT), 5-HT3 receptor (5-HT3R), 5-HT4...
AIMTo observe whether there are differences in the effects of electro-acupuncture (EA) and moxibustion (Mox) rats with visceral hypersensitivity. METHODSEA at 1 mA 3 Mox 43 ℃ 46 were applied to Shangjuxu (ST37, bilateral) acupoints model hypersensitivity.Responses wide dynamic range neurons dorsal horns spinal cord observed through extracellular recordings.Mast cells (MC) activity colons assessed, 5-hydroxytryptamine (5-HT), receptor (5-HT3R) 5-HT4R
Aim . To compare whether there is different effect between electroacupuncture (EA) and moxibustion (Mox) on visceral hypersensitivity (their analgesic effects) in constipation‐predominant irritable bowel syndrome (C‐IBS). Methods EA at 1 mA 3 Mox 43°C 46°C were applied to the Shangjuxu (ST37, bilateral) acupoint rats with C‐IBS normal rats. An abdominal withdrawal reflex (AWR) score was used assess hypersensitivity. Toluidine blue staining mast cell (MC) activity colon of Immunochemistry...
AIM:To identify an appropriate therapeutic regimen for using aconite cake-separated moxibustion to treat diarrhea-predominant irritable bowel syndrome (D-IBS).
Objective. This study explored the mechanism of herb-partitioned moxibustion (HM) on dextran sulfate sodium- (DSS-) induced ulcerative colitis (UC) from miRNA perspective. Methods. Rats were randomly divided into 3 groups [normal control (NC) group, UC model and (UCHM) group]. The UCHM administered 4% DSS for 7 days. group received HM at Tianshu (bilateral, ST25). effect was observed expression profile in colon tissues analyzed. Results. Compared with body weights significantly higher day 14...
To investigate effects moxibustion exerts on A20 expression and regulation of intestinal epithelial tight junctions via the TNF-α-NF-κB-MLCK pathway in Crohn's disease (CD). C57BL/6 wild type (WT) A20IEC−KO mice (48 each) were randomly divided into normal control (NC), model (MC), mesalazine (MESA) herbs-partitioned (HPM) groups (12 per group). An experimental CD was established using 2, 4, 6 trinitrobenzene sulfonic acid. MESA HPM treated with (at Tianshu (ST25) Qihai (CV6)), respectively....
Ulcerative colitis (UC), also known as chronic nonspecific UC, is an inflammatory bowel disease characterized by diffuse colonic mucosal inflammation. The incidence and prevalence of UC have risen markedly, the seriously affects quality life patients, poses a great burden on world health care infrastructure economy.We present 60-year-old man who had ulcerative for more than 10 years, with recurrent abdominal pain, bloody diarrhea mucopurulent stool. treatments sulfasalazine, mesalazine,...
Visceral hypersensitivity is enhanced in irritable bowel syndrome (IBS) patients. Treatment of IBS visceral pain by moxibustion methods has a long history and rich clinical experience. In the clinic, on Tianshu (ST25) Shangjuxu (ST37) acupoints can effectively treat disease with diarrhea symptoms. To investigate regulatory function spinal cord NR1, NR2B, PKC ε protein mRNA expression rats, we did some research. study, found that relieved hyperalgesia status rats. Analgesic effect was similar...
It has been proven that prokineticin 2 (PK2) and its receptor PKR2 play an important role in hyperalgesia, while mild moxibustion can relieve visceral hypersensitivity a rat model of irritable bowel syndrome (IBS). The goal the present study was to determine effects on expression PK2 colon spinal cord IBS model, which induced by colorectal distension using inflatable balloons. After treatment, abdominal withdrawal reflex (AWR) scores were assessed distension; protein mRNA determined...
Crohn’s disease may cause excessive damage and repair in the intestinal epithelium due to its chronic relapsing inflammation. These factors initiate TGF- β 1-Smad pathway activate transcription factor of Snail, Snail-mediated promotes transformation epithelial cells mesenchymal cells, leading fibrosis. Acupuncture moxibustion have been demonstrated prevent fibrosis disease. However, it is not clear whether acupuncture can inhibit by affecting 1-Smad-Snail pathway. This study indicated that...
To explore whether the effect of electroacupuncture (EA) on visceral hypersensitivity (VH) in rats with irritable bowel syndrome (IBS) is related to changes astrocyte activation medial thalamus (MT) and anterior cingulate cortex (ACC).Male Sprague-Dawley were randomly divided into normal control (NC) group, model (MC) fluorocitrate (FCA) group. A was established by neonatal colorectal irritation. In EA needles inserted skin at Tianshu (ST25) Shangjuxu (ST37) acupoints, once a day for 7 days....
To investigate the immune regulation mechanism of herb-partitioned moxibustion in rats with Crohn's disease (CD) focusing on autophagy.Rats were randomly divided into normal (N) group, CD model (M) (MM) (NM) mesalazine (western medicine, Med ) and saline (NS) 10 each group. The prepared by trinitrobenzene sulphonic expect for N group NM After established, MM groups treated at Tianshu (ST25) Qihai (CV6) acupoints once daily 7 days, NS respectively enteric coated tablet days. intervention,...
To observe the effects and safety of clinical common symptoms active Crohn's disease at mild moderate stages treated with acupuncture moxibustion.One hundred two patients were randomly divided into an observation group a control group, 51 cases in each one. Herb-partition moxibustion used group. Herbal cakes Huanglian (coptis chinensis), Fuzi (radix aconiti carmichaeli), Rougui (cinnamomum cassia), Muxiang (radices saussureae), Honghua (carthamus tinctorious), Danshen (the root red-rooted...
A20 inhibits intestinal epithelial cell apoptosis in Crohn's disease, and herbs-partitioned moxibustion (HPM) has been demonstrated to be an effective treatment for disease. However, the mechanism by which HPM reduces disease not thoroughly elucidated date.To elucidate whether exerts its effects upregulating affect a mouse model.In this study, mice with deletion cells (A20IEC-KO) were utilized establish model 2,4,6-trinitrobenzene sulfonic acid (TNBS) administration, as well wild-type mice....