A5076089467- Radio Frequency Integrated Circuit Design
- Acupuncture Treatment Research Studies
- Semiconductor materials and devices
- Advancements in PLL and VCO Technologies
- Advancements in Semiconductor Devices and Circuit Design
- Nanoparticles: synthesis and applications
- Gastrointestinal motility and disorders
- Analog and Mixed-Signal Circuit Design
- 3D IC and TSV technologies
- Inflammatory Bowel Disease
- Traditional Chinese Medicine Studies
- Photonic and Optical Devices
- Selenium in Biological Systems
- Gut microbiota and health
- Complementary and Alternative Medicine Studies
- Antioxidant Activity and Oxidative Stress
- Radiation Effects in Electronics
- Anesthesia and Neurotoxicity Research
- Inflammasome and immune disorders
- Infant Health and Development
- Real-time simulation and control systems
- Pancreatic function and diabetes
- Microwave Engineering and Waveguides
- Healthcare and Venom Research
- Modeling and Simulation Systems
Jiangxi University of Traditional Chinese Medicine
2024
Creative Commons
2023
Yueyang Hospital
2021-2023
Shanghai University of Traditional Chinese Medicine
2013-2023
Shanghai Research Center for Acupuncture and Meridians
2014-2023
Chengdu University of Traditional Chinese Medicine
2023
North China University of Science and Technology
2017-2020
Harbin Medical University
2020
Fudan University
2008-2019
State Council of the People's Republic of China
2018
Type 2 diabetes is a common metabolic disorder related to insulin resistance, or deficiency of secretion, caused by decreased sensitivity and destruction islet structure function. As the second human genome, microbiota has been observed have growing relationship with in recent years. Microbiota imbalance hypothesized be involved regulation energy metabolism inflammatory immune response diabetes. The present study aimed investigate whether fecal transplantation (FMT) could alleviate symptoms...
Background:Whether Crohn's disease [CD] is correlated with brain structural changes unclear. This study examined in grey matter [GM] structures CD patients and their correlation psychological distress.
Although the transcription factor Krüppel-like 5 (KLF5) plays important roles in both inflammation and cancer, mechanism by which this promotes cervical carcinogenesis remains unclear. In study, we demonstrated a potential role for tumour necrosis receptor superfamily member 11a (TNFRSF11a), corresponding gene of is direct binding target KLF5, cell proliferation invasiveness. Coexpression KLF5 TNFRSF11a correlated significantly with tumorigenesis tissues (P < 0.05) manipulation expression...
This letter presents the first demonstration of a silicon-germanium heterojunction bipolar transistor (SiGe HBT) capable operation above one-half terahertz (500 GHz) frequency. An extracted peak unity gain cutoff frequency (f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> ) 510 GHz at 4.5 K was measured for 0.12×1.0 μm <sup xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> SiGe HBT (352 300 K) breakdown voltage BV/sub CEO/ 1.36 V (1.47...
A fully integrated 1.175-2-GHz differentially tuned frequency synthesizer aimed for digital video broadcasting-terrestrial tuners is implemented in a 0.18-mum CMOS process. To maintain phase-noise optimization and loop stability over the entire output range, techniques of constant bandwidth are proposed. The voltage-controlled oscillator gain <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">K</i> <sub...
We report, for the first time, impact of proton irradiation on fourth-generation SiGe heterojunction bipolar transistors (HBTs) having a record peak unity gain cutoff frequency 350 GHz. The implications aggressive vertical scaling observed tolerance is investigated through comparisons pre-and post-radiation ac and dc figures-of-merit to results from prior HBT technology nodes irradiated under identical conditions. In addition, varying breakdown voltage are used probe differences in as...
Lanthanum oxide (La2O3) nanoparticles (NPs) have been widely used in catalytic and photoelectric applications, but the reproductive toxicity is still unclear. This study evaluated of two different-sized La2O3 particles testes.Fifty Kunming mice were randomly divided into five groups. Mice treated with NPs by repeated intragastric administration for 90 days (control, nano-sized 5, 10, 50 mg/kg BW micro-sized BW). control group de-ionised water without NPs. Sperm parameters, testicular...
We present the design and implementation of an ultra-high-speed SiGe BiCMOS track-and-hold amplifier (THA) for use in high-speed analog-to-digital converters. The a degeneration inductor input buffer significantly improves performance THA. THA was fabricated commercially-available 0.25 /spl mu/m 200 GHz HBT process technology. circuit occupies area 1.2 mm/sup 2/, exhibits -49.5 dBc total harmonic distortion (THD) when operated at sampling frequency 12.5 with 3.0 GHz. Operating from 3.5 V...
A low-power, X-band low-noise amplifier (LNA) is presented. Implemented with 180 GHz silicon-germanium (SiGe) heterojunction bipolar transistors (HBTs), the circuit occupies 780times660 mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The LNA exhibits a gain of 11.0 dB at 9.5 GHz, mean noise figure 2.78 across X-band, and an input third-order intercept point -9.1 dBm near while dissipating only 2.5 mW. low-power performance this...
In this paper, we have presented the need for Middle of Line (MOL) Local Interconnects in a fixed layout shape called "Special Constructs" order to make 20nm very compelling technology product migration from 28nm. These constructs are used demonstrate considerable area, cost, and power/performance benefits by enabling efficient manufacturable high density standard cell libraries. Also, these become an essential elements optical lithography based advanced CMOS nodes cost effective scaling...
We present results on the impact of proton irradiation dc and ac characteristics third-generation, 0.12 /spl mu/m 185 GHz SiGe HBTs. Comparisons with prior technology generations are used to assess how structural changes needed enhance performance between second third generation couple observed response. The demonstrate that HBT technologies can successfully maintain their a Mrad-level total dose hardness, without intentional hardening, even when vertically-scaled in order achieve...
We investigate, for the first time, design and implementation of a high-slew rate op-amp in SiGe BiCMOS technology capable operation across very wide temperature ranges, down to deep cryogenic temperatures. achieve monolithic (for any material system) operating reliably 4.3 K. Two variants were implemented using alternative biasing schemes, effects on these their impact overall performance, is investigated
Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) was reported to improve visceral hypersensitivity in rats. Colorectal distension utilized generate a rat model of chronic irritable bowel syndrome. Results showed that abdominal withdrawal reflex scores noticeably increased after establishment. Simultaneously, P2X4 receptor immureactivity significantly the colon spinal cord. pinaverium bromide therapy both markedly decreased rats with hypersensitivity, immunoreactivity These data...
An ultra-high-speed track-and-hold amplifier (THA) using a switched-emitter-follower (SEF) configuration is presented. Implemented in commercially-available 0.18 /spl mu/m 120 GHz SiGe HBT BiCMOS technology, the THA core occupies compact area of only times/ 200 mu/m/sup 2/. The can operate at sampling rate 18 GS/sec with total harmonic distortion (THD) -32.3 dBc, and dissipates 128 mW, significantly smaller than other THAs literature operating similar rates.
Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic hypersensitivity. Immunohistochemistry detect P2X2 P2X3 receptor expression dorsal root ganglia from rats with Results demonstrated that abdominal withdrawal reflex scores obviously increased following establishment the model, indicating Simultaneously, ganglia. After bilateral electroacupuncture Tianshu, decreased These...
Intestinal fibrosis is the main pathological process in Crohn’s disease (CD); acupuncture and moxibustion can inhibit of CD rats, but regulatory mechanism remains unknown. The present study observed effect on extracellular signal-regulated kinase (ERK) signaling pathway rat. result shows that phosphorylation Ras, Raf-1, MEK-1, ERK-1/2 proteins expression corresponding mRNAs colon tissue rat were significantly higher than normal control group. Both treatments with mild herb-separated reduced...
Continuous process-level and system-level innovation has driven Moore's Law scaling for the last fifty years, will continue to do so in next decades. In two decades, there been an acceleration of new materials devices into semiconductor manufacturing, such as low-k, strained Si, high-k, FinFET, order process cost scaling. At same time, ever increasing component integration on SoCs further scaling, allowing current mobile era take shape. decade, focus SoC be patterning low-resistance side,...
Ulcerative colitis (UC), also known as chronic nonspecific UC, is an inflammatory bowel disease characterized by diffuse colonic mucosal inflammation. The incidence and prevalence of UC have risen markedly, the seriously affects quality life patients, poses a great burden on world health care infrastructure economy.We present 60-year-old man who had ulcerative for more than 10 years, with recurrent abdominal pain, bloody diarrhea mucopurulent stool. treatments sulfasalazine, mesalazine,...
This work presents the first experimental results on effects of 63.3 MeV proton irradiation 60 GHz monolithic point-to-point broadband space data link transceiver building blocks implemented in a 200 SiGe heterojunction bipolar transistor (HBT) technology. A low-noise amplifier and voltage-controlled oscillator were each irradiated to fluences 5.0/spl times/10/sup 13/ p/cm/sup 2/. The device circuit level performance degradation associated with these extreme is found be minimal, suggesting...