Lixia Zhang

ORCID: 0000-0003-2560-0048
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About
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Liver Disease Diagnosis and Treatment
  • Tea Polyphenols and Effects
  • Gestational Diabetes Research and Management
  • Radiomics and Machine Learning in Medical Imaging
  • Mycobacterium research and diagnosis
  • Traditional Chinese Medicine Studies
  • Wheat and Barley Genetics and Pathology
  • Traditional Chinese Medicine Analysis
  • Osteoarthritis Treatment and Mechanisms
  • Healthcare and Venom Research
  • Reproductive Biology and Fertility
  • Chronic Disease Management Strategies
  • Cancer-related molecular mechanisms research
  • Systemic Lupus Erythematosus Research
  • Tuberculosis Research and Epidemiology
  • Chronic Lymphocytic Leukemia Research
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health
  • Plant pathogens and resistance mechanisms
  • Autoimmune and Inflammatory Disorders Research
  • Biosimilars and Bioanalytical Methods
  • Viral Infections and Immunology Research
  • Cardiovascular Health and Risk Factors
  • Respiratory viral infections research

Sichuan Cancer Hospital
2017-2025

University of Electronic Science and Technology of China
2017-2025

Northwest A&F University
2024

Women's Hospital, School of Medicine, Zhejiang University
2019-2024

Shandong Agricultural University
2007-2024

Daqing Oilfield General Hospital
2024

Nanchang University
2012-2024

University of Manitoba
1996-2023

Shandong University
2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2023

We aimed to evaluate the validity and reliability of multiple screening measures for depression anxiety use in clinical care people with sclerosis (MS).Participants MS completed Patient Health Questionnaire (PHQ-9), Hospital Anxiety Depression Scale (HADS), Kessler-6 Distress Scale, PROMIS Emotional Short-Form 8a (PROMIS Depression) Anxiety), Generalized Disorder 7-item (GAD-7), Overall Severity Impairment (OASIS). A subgroup repeated two weeks later. All participants also a Structured...

10.1016/j.msard.2017.12.007 article EN cc-by-nc-nd Multiple Sclerosis and Related Disorders 2017-12-16

We evaluated the validity and reliability of multiple symptom scales for depression anxiety persons with inflammatory bowel disease (IBD). IBD participants in a cohort study completed Structured Clinical Interview DSM-IV-TR Axis I Disorders (SCID) Patient Health Questionnaire (PHQ-9), Hospital Anxiety Depression Scale (HADS), Kessler-6 Distress Scale, PROMIS Emotional Short-Form 8a (PROMIS Depression) Anxiety), Generalized Disorder 7-item Overall Severity Impairment Scale. computed...

10.1093/ibd/izy068 article EN Inflammatory Bowel Diseases 2018-04-12

To test the validity and reliability of screening instruments for depression anxiety in rheumatoid arthritis (RA).Participants with RA completed Patient Health Questionnaire (PHQ-2 or PHQ-9), Reported Outcomes Measurement Information System short form 8a 8a, Hospital Anxiety Depression Scale score (HADS-A) (HADS-D), Overall Severity Impairment Scale, Generalized Disorder 2- 7-item scales, Kessler-6 scale. Clinical disorders were confirmed using Structured Interview Diagnostic Statistical...

10.1002/acr.24011 article EN cc-by-nc-nd Arthritis Care & Research 2019-06-14

The mental health (MH) of older adults is a prominent public concern. However, research regarding the impact emerging Internet use on MH among remains limited, particularly in transitional economies experiencing rapidly aging population such as China. Thus, to address this gap, study uses data from 2013–2018 waves China Health and Retirement Longitudinal Study. To investigate causal relationship between explore underlying channels through which operates. results reveal notable positive...

10.1016/j.heliyon.2024.e25397 article EN cc-by-nc-nd Heliyon 2024-02-01

We aimed to develop and validate a nomogram combining bi-regional radiomics features from multimodal magnetic resonance imaging (MRI) clinicoradiological characteristics preoperatively predict microvascular invasion (MVI) of hepatocellular carcinoma (HCC).A total 267 HCC patients were divided into training (n=194) validation (n=73) cohorts according MRI data. Bi-regional extracted whole tumors peritumoral regions in MRI. The minimum redundancy maximum relevance (mRMR) algorithm was applied...

10.21037/qims.2019.09.07 article EN Quantitative Imaging in Medicine and Surgery 2019-09-01

Tea is a popular beverage with characteristic functional and flavor qualities, known to be rich in bioactive metabolites such as tea polyphenols theanine. Recently, varieties variations leaf color have been widely used agriculture production due their potential advantages terms of quality. Numerous studies genome, transcriptome, metabolome, proteome, lipidome methods uncover the causes investigate impacts on accumulation crucial plants. Through comprehensive review various omics...

10.3390/plants13030426 article EN cc-by Plants 2024-01-31

Excessive skin scars due to elective operations or trauma represent a challenging clinical problem. Pathophysiology of hypertrophic entails prolonged inflammatory and proliferative phase wound healing. Over expression TGF-β1 COX-2 play key regulatory roles the aberrant fibrogenic responses proinflammatory mediators. When we silenced simultaneously in primary human fibroblasts, marked increase apoptotic cell population occurred contrast those only treated with either siRNA alone. Furthermore,...

10.18632/oncotarget.20869 article EN Oncotarget 2017-09-14

The role of HbA1c in women with gestational diabetes mellitus (GDM) is still unclear, particularly the Asian population.To investigate association between levels and adverse outcomes considering maternal age, pre-pregnancy body mass index (BMI), weight gain (GWG) GDM.A retrospective study included 2048 GDM singleton live births. Using logistic regression, associations pregnancy were assessed.Compared to ≤ 5.0%, was significantly associated macrosomia (aOR 2.63,95%CI1.61,4.31),...

10.3389/fendo.2023.1105899 article EN cc-by Frontiers in Endocrinology 2023-03-16

Liver cancer poses significant health challenges worldwide, particularly for ethnic minority populations, who often face barriers such as cultural differences, limited literacy, and inadequate access to healthcare, contributing poorer self-management treatment outcomes. Existing tools do not adequately address the unique needs of liver patients, necessitating development a culturally tailored assessment scale. Grounded in Health Belief Model, this study developed behavior scale specifically...

10.1186/s12913-025-12272-0 article EN cc-by-nc-nd BMC Health Services Research 2025-02-25

To examine the safety of outpatient clinic simultaneous intravenous fundus fluorescein angiography (IVFA) and indocyanine green (ICGA) in patients with any/all drug allergy history.In a single-center retrospective study conducted from February 2007 to March 2011, 390 consecutive outpatients history 3426 without underwent IVFA ICGA. The detailed history, symptoms time adverse reaction during ICGA were recorded all patients.Of who received ICGA, 28 (7.2%) had an reaction. In contrast, 145...

10.1089/jop.2011.0221 article EN Journal of Ocular Pharmacology and Therapeutics 2012-02-28

To evaluate the potential application of computed tomography (CT) radiomics in prediction BRCA1-associated protein 1 (BAP1) mutation status patients with clear-cell renal cell carcinoma (ccRCC). In this retrospective study, clinical and CT imaging data 54 were retrieved from The Cancer Genome Atlas-Kidney Renal Clear Cell Carcinoma database. Among these, 45 had wild-type BAP1 nine mutation. texture features tumor images extracted using Matlab-based IBEX package. produce class-balanced...

10.3389/fonc.2020.00279 article EN cc-by Frontiers in Oncology 2020-02-28

Importance: Consumers purchase a wide variety of consumer products and come into contact with these on daily basis. Manufacturers invest deeply in developing new or improving existing products, order to produce positive impact the lives consumers. Objective: The goal this study was determine over-the-counter skin care quality life (QoL) female Design Measures: A QoL instrument developed for (the Farage an added Skin Care Module) used assess 28-day facial regimen using commercially available...

10.3390/cosmetics7030059 article EN cc-by Cosmetics 2020-07-24

A previous study suggested a younger age at menarche (AAM) among daughters of heavy prenatal smokers, especially non-Whites. The present was designed to evaluate that association in another population and examine other factors may be related AAM. We analysed data from the Collaborative Perinatal Project, nationwide longitudinal pregnant women their children conducted 1959-66. At three sites, with predominance Black participants (80%), AAM ascertained offspring when they were young adults....

10.1111/j.1365-3016.2008.00948.x article EN Paediatric and Perinatal Epidemiology 2008-05-20

Hemodynamic differentiation between pulmonary arterial hypertension (PAH) and postcapillary (PH) is important because treatment options are strikingly different for the two disease subsets. Whereas patients with PAH can be treated effectively targeted therapies, their use in PH currently not recommended. Our aim was to establish an algorithm identify who likely experience a significant hemodynamic response.We determined cutoffs discriminate idiopathic large database of 4,363 stable...

10.1378/chest.15-0928 article EN cc-by-nc-nd CHEST Journal 2015-10-22

Objectives: For rheumatoid arthritis (RA) patients failing to achieve treatment targets with conventional synthetic disease-modifying antirheumatic drugs, tumor necrosis factor (TNF)-α inhibitors (anti-TNF therapies) are the primary first-line biologic therapy. In a cross-cohort, cross-platform study, we developed molecular test that predicts inadequate response anti-TNF therapies in biologic-naive RA patients. Materials and Methods: To identify predictive biomarkers, comprehensive human...

10.1089/nsm.2020.0007 article EN Network and Systems Medicine 2020-07-01

To evaluate the influence of genetic variants and clinical characteristics on risk gestational diabetes mellitus (GDM) to construct verify a prediction model GDM in early pregnancy. Four hundred seventy five women with 487 without, as control, were included Both groups had complete genotyping results data. They randomly divided into trial cohort (70%) test (30%). Then, validation cohort, including 985 pregnant women, was used for external pregnancy model. We found maternal age, gravidity,...

10.1186/s13098-022-00788-y article EN cc-by Diabetology & Metabolic Syndrome 2022-01-24
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