Ahmadreza Sebzari

ORCID: 0000-0001-5424-0577
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Research Areas
  • Breast Cancer Treatment Studies
  • Neutropenia and Cancer Infections
  • Nonmelanoma Skin Cancer Studies
  • Mental Health and Well-being
  • Complementary and Alternative Medicine Studies
  • Palliative Care and End-of-Life Issues
  • Cancer survivorship and care
  • Breast Implant and Reconstruction
  • Family Support in Illness
  • Biopolymer Synthesis and Applications
  • BRCA gene mutations in cancer
  • Advanced Radiotherapy Techniques
  • Immunotherapy and Immune Responses
  • Oral Health Pathology and Treatment
  • Family Caregiving in Mental Illness
  • Inflammatory Biomarkers in Disease Prognosis
  • Nigella sativa pharmacological applications
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • MicroRNA in disease regulation
  • Management of metastatic bone disease
  • HER2/EGFR in Cancer Research
  • RNA Research and Splicing
  • Breast Lesions and Carcinomas
  • Cardiac tumors and thrombi
  • Cancer-related cognitive impairment studies

Birjand University of Medical Sciences
2016-2024

Tehran University of Medical Sciences
2016

Resistance to trastuzumab has become a limiting factor for therapeutic efficacy of human epidermal growth 2 (HER2)-positive breast cancer. Different expression levels miRNAs in cancer cells have been associated with poor prognosis and response chemotherapy. The aim this study was evaluate that were thought be HER2-positive chemoresistance. In study, the relative candidate U6 RNA evaluated trastuzumab-resistant trastuzumab-sensitive using real-time PCR. Our results demonstrated miR-23b-3p,...

10.1089/dna.2018.4427 article EN DNA and Cell Biology 2019-01-31

Prostate cancer (PCa) is one of the two solid malignancies in which a higher T cell infiltration tumor microenvironment (TME) corresponds with worse prognosis for tumor. The inability cells to eliminate despite an increase their number reinforces possibility impaired antigen presentation. In this study, we investigated TME at single-cell resolution understand molecular function and communication dendritic (DCs) (as professional antigen-presenting cells). According our data, stimulate...

10.1016/j.heliyon.2023.e15694 article EN cc-by-nc-nd Heliyon 2023-04-23

Abstract Background The adverse effects of methotrexate (MTX) mainly hepatotoxicity restrict its clinical use. This study was designed to investigate the protective saffron ( Crocus sativus ) (CS) extract on MTX-induced hepatotoxicity. Methods Twenty-eight male Wistar rats randomly divided into four equal groups. Except for control, all groups received a single intraperitoneal (i.p.) injection MTX 3rd day study. CS given (80 mg/kg i.p.) 3 days before and continued next 7 (Pre&Post-CS...

10.1515/jcim-2019-0201 article EN Journal of Complementary and Integrative Medicine 2019-10-26

Bckground: Adjuvant radiation therapy is commonly administered following breast-conserving surgery for breast cancer patients. Hypofractionated radiotherapy can significantly reduce the waiting time radiotherapy, working load on machines, patient visits to departments and medical costs. Material/Methods: Fifty-two patients with operable (pT1-3pN0M0) who underwent conservation in Tehran Cancer Institute during January 2011 2012, were randomly assigned undergo two arms (hypofractionated arm 30...

10.22034/apjcp.2016.17.11.4819 article EN PubMed 2016-11-01

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kazemian A, Babaei M, Lashkari et al. Adjuvant high-dose-rate brachytherapy in the management of oral cavity cancers: 5 years experience Iran. Journal Contemporary Brachytherapy. 2017;9(4):323-329. doi:10.5114/jcb.2017.69806. APA Kazemian, A., Babaei, M., Lashkari, Ghalehtaki, R., Garajei, & Motiee-Langroudi, M. (2017). Brachytherapy, 9(4), 323-329. https://doi.org/10.5114/jcb.2017.69806 Chicago Ali, Mohammad...

10.5114/jcb.2017.69806 article EN cc-by-nc-sa Journal of Contemporary Brachytherapy 2017-01-01

Background: In patients with advanced cancer, family caregivers are crucial in providing care throughout the illness, particularly towards end of life. These often face unique challenges and emotions that may differ significantly from those experienced by other members following patient’s death. Objectives: The purpose this study was to explore experiences loss a patient cancer. Methods: A qualitative conducted Iran June 2023 January 2024 after death Using purposive sampling, face-to-face,...

10.5812/mcj-146988 article EN Modern Care Journal 2024-05-08

Background: Breast cancer (BC) is well-known as the most common malignancy and first leading cause of cancer-related death among women worldwide. Evidence suggests that familial history age are important risk factors for development this disease in Iran. Mutations BRCA1 BRCA2 genes 5 to 10% hereditary BC. Recent studies demonstrated mutations were observed high-risk with family histories However, date, have not been elucidated BC patients from east The purpose study was analyze patient South...

10.47176/mjiri.33.105 article EN cc-by-nc Medical Journal of the Islamic Republic of Iran 2019-10-30

Background: Breast cancer diagnosis and treatment can negatively impact the quality of life lead to symptoms such as insomnia, depression, anxiety. Internet-delivered interventions may reduce these in patients with limited access face-to-face psychological treatments. Objectives: This study aimed determine effect online mindfulness-based stress reduction (MBSR) intervention on sleep women breast Birjand City. Methods: In this randomized controlled clinical trial, 62 eligible undergoing...

10.5812/mcj-134503 article EN Modern Care Journal 2023-08-22

The effect of foot reflexology massage on the stress and neuropathic pain caused by chemotherapy in women with breast cancer genitalia

10.32592/jbirjandunivmedsci.2019.26.1.101 article EN cc-by-nc Journal of Birjand University of Medical Sciences 2019-02-01

Evaluation of Fecal Colonization with Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae and Risk Factors among Cancer Patients in Eastern Iran

10.52547/iem.7.4.277 article EN cc-by-nc Infection Epidemiology and Microbiology 2021-11-01

Background: The axillary and supraclavicular nodal volume treatment results in improvement of local control survival after breast conserving surgery (BCS) or modified radical mastectomy (MRM). Studies on the depth these nodes have questioned consistent use standard fields for all patients. This study was done to assess dose delivery lymph with conventional techniques according body mass index (BMI).Methods: Twenty six patients cancer undergoing were included computed tomography (CT)...

10.19187/abc.20163114-18 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2016-03-01

Introduction: This study explores the link between inflammatory markers and hospital outcomes in febrile neutropenic patients with solid cancers- a complication caused by systemic chemotherapy that can lead to hospitalization requires timely diagnosis treatment reduce fatalities. Methods: was conducted 2017 at Vali-e-Asr Hospital Birjand 22 participants. Blood samples were collected measure indexes. The documented various outcomes, including duration of neutropenia fever correction, length...

10.34172/ijbsm.43631 article EN cc-by International journal of basic science in medicine 2023-11-15

مقدمه:سرطان پستان، شایع‌ترین بدخیمی در زنان و به‌‌عنوان اولین علت مرگ‌و‌میر ناشی از سرطان شناخته می‌شود.این بیماری به شدت ناهمگن بوده تحت تأثیر عوامل ژنتیکی محیطی به‌وجود می‌آید. جهش دو ژن بسیار پرنفوذ BRCA1 BRCA2 که نقش مهمی ترمیم DNA دارند، اصلی 30-20% سرطان‌های پستان ارثی شده است. مطالعه حاضر با هدف بررسی فراوانی جهش‌های افراد مبتلا جمعیت خراسان جنوبی انجام شد. روش‌کار:این توصیفی بین سال‌های 96-1394 بر روی ۸۸ بیمار شهر بیرجند نمونه خون جمع‌آوری قطعات مورد نظر استفاده استخراج بیماران تکنیک...

10.22038/ijogi.2018.10711 article FA DOAJ (DOAJ: Directory of Open Access Journals) 2018-04-21

Introduction: The functionality and quality of any treatment planning system (TPS) strongly depends on the type Algorithm which is used by it. Obviously, role dose distribution algorithms in calculation prescribed inside tumor modern radiotherapy techniques has more important than past to achieve best clinical outcomes, especially tumors are placed lung or near it like Esophagus cancer. The aim this study evaluate comparison efficiency accuracy two algorithms, Clarkson Superposition using...

10.22038/ijmp.2018.11884 article EN 2018-12-01
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