A5062277192- HIV/AIDS Research and Interventions
- Reproductive tract infections research
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- Syphilis Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- Genital Health and Disease
- Herpesvirus Infections and Treatments
- Autoimmune Bullous Skin Diseases
- Infectious Diseases and Mycology
- Virology and Viral Diseases
- Cutaneous Melanoma Detection and Management
- Poxvirus research and outbreaks
- Nonmelanoma Skin Cancer Studies
- Drug-Induced Adverse Reactions
- Bacillus and Francisella bacterial research
- Cancer and Skin Lesions
- Cutaneous lymphoproliferative disorders research
- Salivary Gland Tumors Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Skin and Cellular Biology Research
- Dermatological and COVID-19 studies
- Actinomycetales infections and treatment
- LGBTQ Health, Identity, and Policy
- Heparin-Induced Thrombocytopenia and Thrombosis
National Skin Centre
2016-2025
National University Health System
2024
National Centre for Infectious Diseases
2019
Duke-NUS Medical School
2019
Ministry of Health
2012-2018
Tan Tock Seng Hospital
2013
Sexualised substance use, or 'chemsex' has been shown to be a major factor driving the syndemic of HIV/AIDS in communities gay, bisexual, and other men who have sex with (GBMSM) around world. However, there is paucity research on chemsex among GBMSM Singapore due punitive drug laws criminalisation sexual behaviour between men. This qualitative descriptive study first explore perceptions towards, motivators engaging in, barriers addressing harms associated Singapore. We conducted 30...
Genital and perianal ulcers seen in patients with HIV are commonly due to herpes simplex virus (HSV) infection. While it is well known that the characteristic presentation of HSV a vesicular rash or crops erosions, clinical genital infection varied can assume vegetative, hypertrophic, condyloma-like, nodular, ulcerative tumour-like nodules plaques. These unusual presentations often lead delayed diagnosis. We describe five immunocompromised HIV-positive CD4 counts ranging from 114 326...
Abstract Introduction In August 2024, the World Health Organization (WHO) declared a public health emergency due to rapid spread of mpox in African and beyond. International travel controls (ITCs), such as screening viral testing, could help avoid/delay global monkeypox virus (MPXV), fostering preparedness response efforts. However, it is not clear whether tests at immigration are sufficient avoid importation MPXV which samples should be used on tests. Methods We conducted simulation study...
Gonorrhea is the second most common sexually transmitted disease notified in Singapore 2023. Evidence suggests that 4CMenB vaccine designed to protect against Neisseria meningitidis infection may offer partial cross-protection gonorrhea. This generated interest using for purpose of staving gonorrhea transmission. We explored efficacy potential vaccination strategies context historically declining incidence. employed an integrated transmission-dynamic model, calibrated Bayesian methods local...
Although pre-exposure prophylaxis (PrEP) has been available in Singapore since 2016, its uptake among gay, bisexual and other men-who-have-sex-with-men (GBMSM) is low. The iPARTY study was established to evaluate the acceptability feasibility of PrEP a teleconsultation service for young GBMSM aged 18 29 years. A total 53 were enrolled study. They had 5 in-person consultations teleconsultations, at 12-week intervals. Laboratory tests quarterly baseline surveys performed assess adherence,...
Monkeypox is a global health emergency. Prior to 2022, there were few reports of monkeypox outside endemic countries, which mostly travel-related. Since May an exponential increase in infections previously non-endemic countries has been reported. Unlike previous outbreaks monkeypox, zoonotically transmitted and presented with generalised vesicular eruptions after prodromal symptoms, cases the current outbreak feature significant travel sexual history, atypical localised genital unpredictable...
Purpose: To report the presentations of syphilitic uveitides in Singapore.Methods: Retrospective noncomparative observational case series 18 eyes from 12 patients with ocular syphilis between 2004 and 2009.Results: Patients were mainly male (91.7%). Median age was 49.5 (24–84) years. Initial visual acuity varied 6/6 to counting fingers (CF) ≥6/12 7 (38.8%). Blurring vision (n = 11, 61.1%) most common presenting complaint. Anterior uveitis panuveitis both 6, 33.3%). Treponemal nontreponemal...
Amidst recent trends in rising rates of chlamydia and gonorrhea among Singaporean adolescents, there are limited data on risk factors associated with these infections that may inform prevention strategies this population.A cross-sectional study positivity was conducted 1458 sexually active heterosexual adolescents between 14 19 years old attending the national public transmitted infection clinic from 2006 to 2013. The association demographic behavioral characteristics assessed by crude...
Mycoplasma genitalium is an emerging sexually transmitted infection, with increasing rates of resistance to fluroquinolones and macrolides, the recommended treatments. Despite this, M. not part routine screening for Sexually Transmitted Infections (STIs) in many countries prevalence infection patterns disease remain be determined populations. Such data particular importance light reported rise antibiotic isolates.Urine urethral swab samples were collected from primary public sexual health...
Gay, bisexual, and other men who have sex with (GBMSM) are at disproportionately higher risk of acquiring HIV sexually transmitted infections (STI). While HIV/STI testing rates among GBMSM increasing worldwide, they remain suboptimal in a variety settings. many studies attempted to evaluate the efficacy community-based campaigns, including peer reminder-based interventions on testing, however few do so for web drama series.This study evaluates effectiveness popular video series developed by...
A distributed personal health information management system (D-PHIMS) has been tested at a nursing home for the senior citizens (NHSC) in Singapore. The (PHIMS) from University of Washington was customized to Singapore's context teledermatology. clinical trial commenced October 2005 is ongoing and survey results obtained indicate that participants are satisfied with D-PHIMS system. diagnosis treatment recommendations made by dermatologists using module were effective most cases based on...
To the Editor: A 37-year-old Burmese woman presented with tender nodules of 6-week duration on distal aspect her legs, which appeared a day after receiving second dose tozinameran vaccination. She previously had erythema nodosum (EN) 10 years ago, was related to pulmonary tuberculosis (PTB). completed treatment for PTB at that time, and there complete resolution prior episode EN till time presentation. computed tomography scan thorax obtained several months showed no evidence active PTB,...
There is a lack of representative samples to provide reliable and accurate seroprevalence sexually transmitted infections (STIs) human immunodeficiency virus (HIV) as well behavioural information among men who have sex with (MSM) in Singapore. We used respondent driven sampling (RDS) recruit MSM. Participants completed survey by Asian Internet MSM Sex Survey (AIMSS) were tested for HIV syphilis. compared the characteristics RDS participants STI diagnosis against those did not any past 6...
Gay, bisexual and queer (GBQ) men are at disproportionately higher risk of acquiring HIV other sexually transmitted infections (STI). While HIV/STI testing rates among GBQ increasing worldwide, they remain suboptimal in a variety settings. The study is pragmatic randomised controlled trial designed to evaluate an online video series developed by community-based organisation Singapore for men. A total 300 HIV-negative aged 18-29 years old will be recruited this study. Participants...
This mixed methods study aims to describe 1) characteristics of the population treated with non-occupational post-exposure prophylaxis (nPEP), 2) predictors loss follow-up (LTFU) and nPEP adherence, 3) evaluate prescribing practices against current management guideline.This was conducted at Department Sexually Transmitted Infections Control Clinic in Singapore using clinical data from 2010 2016. Explanatory sequential method design adopted. Predictors LTFU adherence were assessed modified...
Background Genital warts (GW) are a common sexually transmissible infection (STI) among young adults and associated with poor quality of life (QoL). We investigated the functional psychosocial effect GW on Singaporean patients evaluated for any variations in QoL between genders.Patients completed standard questionnaire containing Short Form-36 (SF-36) health survey Cuestionario Específico para Condiloma Acuminado cross-sectional survey. deficits were determined by comparing SF-36 scores...
PrEP is effective in preventing HIV transmission among at-risk HIV-negative MSM. A qualitative descriptive study with five focus group discussions (N = 33) involving a purposively recruited sample of Singaporean MSM was conducted from August 2016 to April 2017 understand local perspectives on potential barriers and motivators the adoption PrEP, prior implementation services Singapore. Knowledge high, many viewed as an attractive alternative condoms for prevention. Concerns about included...
Using a cross-sectional survey, we examined the gender differences in prevalence of and factors associated with anal sex among adolescents attending only public STI clinic Singapore. Data were collected from 1035 sexually active aged 14 to 19 analyzed using Poisson regression. Prevalence intercourse was 28%, significantly more females (32%) than males (23%) ever engaged it. On multivariate analysis, for both genders oral nonuse contraception at last sex. For males, younger age sexual debut...
Primary care physicians manage a significant number of sexually transmissible infections (STI); however, there has not been survey to assess the standard medical care, completeness notifications, provision counselling and contact tracing by primary in Singapore.An anonymous postal was conducted which 1557 questionnaires were mailed out general practitioners (GP), government emergency department doctors.In all, 736 (47.3%) returned, majority respondents graduates from local school, worked...