A5017041333- Mycobacterium research and diagnosis
- Dysphagia Assessment and Management
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Retinal Imaging and Analysis
- Physics of Superconductivity and Magnetism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Respiratory and Cough-Related Research
- Helicobacter pylori-related gastroenterology studies
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Retinal Diseases and Treatments
- Hormonal and reproductive studies
- Diet, Metabolism, and Disease
- Lipoproteins and Cardiovascular Health
- Adipose Tissue and Metabolism
- Advanced Condensed Matter Physics
- Nursing Diagnosis and Documentation
- Peroxisome Proliferator-Activated Receptors
- Magnetic and transport properties of perovskites and related materials
- Antioxidant Activity and Oxidative Stress
- Metabolism and Genetic Disorders
- Fatty Acid Research and Health
- Mercury impact and mitigation studies
- Salivary Gland Disorders and Functions
Nagasaki University
2020-2022
Josai International University
2022
Fukujuji Hospital
2015-2021
Japan Anti Tuberculosis Association
2015-2021
Hiroshima University
2000-2015
Synaptic Research (United States)
1993-1996
Tokyo University of Science
1986
The role of the codon 54 polymorphism fatty acid-binding protein 2 (FABP2) gene on fat metabolism has been controversial. Assuming that effects were modulated by gender and obesity which related to lipid glucose metabolism, we investigated this its effect according such factors.Subjects Japanese-Americans (123 men 126 women) who diagnosed as non-diabetic a 75 g oral tolerance test at baseline.During approximately 7.8 years, 49 (24 25 with type diabetes. In Cox proportional hazards model, was...
The purpose of our study was to clarify whether subtle cortisol-producing tumors, such as not only subclinical Cushing's syndrome (SubCS) but also hypercortisolism (SH), influence the prevalence hypertension, since numerous basic research studies have noted that glucocorticoid excess influences blood pressure.80 patients with adrenocortical adenomas (39 women and 41 men; mean age 62.1 years) were enrolled. SubCS diagnosed using a diagnostic criteria, SH presence serum cortisol level greater...
Erectile dysfunction frequently occurs with diabetes mellitus. A survey of diabetic men was conducted by anonymous questionnaire to investigate the associations erectile various predictive factors. total 112 males without an obvious history were available for analyses. The mean age and duration 53.7 +/- 12.2 years 10.2 8.6 (mean standard deviation), respectively. included questions on presence or absence smoking, hypertension, libido subjective symptoms neuropathy that may be associated...
BACKGROUND: Previous studies have shown a reduction in health-related quality of life (HRQoL) patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD). However, the causes this decline and factors that contribute to it are unknown. This study was conducted analyse association between St George´s Respiratory Questionnaire (SGRQ) clinical parameters, including age, duration, body composition, function, chest X-ray findings, blood data physical function. METHODS: We performed...
Arterial stiffness is an independent predictor of cardiovascular disease, but the impact post-challenge hyperglycaemia on arterial unknown. To investigate association between and hyperglycaemia, we measured second derivative photoplethysmogram as indicator stiffness.This study was done in 159 asymptomatic Japanese men aged 50.7 +/- 13.0 years. All subjects underwent a 75-g oral glucose tolerance test measurement photoplethysmogram.According to World Health Organization criteria (1998), 110...
The experience and causes of pain in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) have not been clarified.This study aimed to determine the prevalence severity bodily (BP) NTM-PD. We also investigated clinical indicators that contribute pain.We used a retrospective cross-sectional design. participants were 114 NTM-PD (109 women) mean age 65 years. measured using 2 items from 36-Item Short Form Survey version (SF-36), BP score was calculated. Functional limitation due...
BACKGROUND: The presence of depressive symptoms in patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD) is an important research topic; however, the prevalence and factors that influence their development are unclear.OBJECTIVE: To analyse association between CES-D (Center for Epidemiological Studies Depression Scale) scores clinical parameters such as age, duration, function, imaging findings, blood data, physical functions, sleep disturbances, respiratory health-related...
The objective of this study was to administer commonly used tools, the Center for Epidemiological Studies Depression Scale (CES-D) and Hospital Anxiety – subscale (HADS-D), screen depressive symptoms in patients with nontuberculous mycobacterial pulmonary disease (NTM-PD). In addition, we sought identify whether differences existed prevalence as assessed by CES-D HADS-D, various predictors depression. presence 95 NTM-PD using HADS-D. Data regarding age, body mass index, function, dyspnea,...
Sjögren's syndrome (SS) is a chronic autoimmune disease that mainly damages the salivary and lacrimal glands. Immune complex (IC) formation triggers local inflammation through IC deposition decreased antigen function. Some ICs can leak from lesion into saliva, but no have been reported to date. We used immune complexome analysis comprehensively identify antigens incorporated (IC-antigens) in saliva samples patients with SS (n = 9) or xerostomia 7). Neutrophil defensin 1 (67%), small...
Patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD) have impaired exercise capacity, but the underlying factors are unknown. We investigated characteristics of patients NTM-PD and capacity.In total, 149 participated in this study. completed incremental shuttle walk test (ISWT) to assess capacity. Peripheral muscle strength function were also assessed. Radiological findings classified into three phenotypes: non-cavitary nodular bronchiectatic (NC-NB) form, cavitary...
The aim of this study was to examine relationships between low density lipoprotein (LDL) metabolism, in vitro binding, and particle size.Twenty four subjects, 17 men 7 women, had elevated plasma total cholesterol (TC), ranging from 174 232 mg/dl, LDL (LDLC) 113 195 mg/dl after 12 weeks on aStep I diet.The fractional clearance rate (FCR) for ranged 0.233 0.619 pools/day (0.366 f 0.021) significantly correlated with triglycerides (TG) (P < 0.05).Although there no relation FCR binding the group...
Abstract Background: Nontuberculous mycobacterium pulmonary disease (NTM-PD) is a progressive condition characterized by exercise intolerance and impaired health-related quality of life (HRQOL). NTM-PD sometimes treated with surgery in combination medication, but little known about the postoperative physical function HRQOL. This study aimed to investigate capacity HRQOL patients preoperatively 6 months postoperatively. Methods: prospective observational included was conducted at Fukujuji...
<b>Introduction:</b> Pulmonary rehabilitation (PR) is an established programme for the management of patients with chronic obstructive pulmonary disease (COPD). However, a significant proportion drop out PR. <b>Aims:</b> The aim this study to determine factors that may contribute dropout from our PR programme. <b>Methods:</b> We reviewed medical charts 41 COPD who participated in 12-week supervised outpatient Fukujuji Hospital. Data collected included clinical and demographic...
Purpose The RGB colour space was converted into seven different spaces: XYZ, CMY, HSL, HSV, HSI, L*a*b* and L*u*v*. L*u*v* presented optimal results, with the highest sensitivity best reproducibility. We employed three-dimensional analysis of spaces to detect early diabetic retinopathy. Methods Six patients small haemorrhages, hard exudates photocoagulation marks were evaluated using fundus photography, which revealed image artefacts in fundi some patients. constructed an experimental device...
Purpose In Japan, the four major diseases which cause loss of eyesight are glaucoma, diabetic retinopathy, pigmentary retinal degeneration, and age-related macular degeneration. We developed an ophthalmic examination apparatus having functions fundus camera, microperimetry, electroretinography, visual acuity testing, designed to diagnose multiple result in eyesight. Methods constructed experimental device with same optical system as a camera. The has previously been used for research...