A5084070939- Testicular diseases and treatments
- Urological Disorders and Treatments
- Hernia repair and management
- Congenital gastrointestinal and neural anomalies
- Sexual Differentiation and Disorders
- Pelvic floor disorders treatments
- Esophageal and GI Pathology
- Effects and risks of endocrine disrupting chemicals
- Birth, Development, and Health
- Pregnancy-related medical research
- Urologic and reproductive health conditions
- Congenital Diaphragmatic Hernia Studies
- Diverticular Disease and Complications
- Congenital Anomalies and Fetal Surgery
- Sperm and Testicular Function
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Pediatric Urology and Nephrology Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatic function and diabetes
- Anesthesia and Neurotoxicity Research
- Anorectal Disease Treatments and Outcomes
- Abdominal Surgery and Complications
- Regulation of Appetite and Obesity
National Hospital Organization Kochi National Hospital
2024
National Hospital Organization
2016-2023
Kitakyushu Municipal Medical Center
2007-2023
Kokura Memorial Hospital
2014-2023
Wakayama Rosai Hospital
2011-2020
Saga-Ken Medical Centre Koseikan
2013-2015
Wakayama Medical University
2004-2010
Saga Prefectural Education Center
2010
Kyushu University
1996-2008
University of Chicago
2006
We investigated the relationship between tumor blood-flow measurement based on perfusion imaging by arterial spin-labeling (ASL-PI) and histopathologic findings in brain tumors.We used ASL-PI to examine 35 patients with tumors, including 11 gliomas, 9 meningiomas, schwannomas, 1 diffuse large B-cell lymphoma, 4 hemangioblastomas, metastatic tumor. As an index of perfusion, relative signal intensity (SI) each (%Signal intensity) was determined as a percentage maximal SI within per averaged...
Ghrelin is a newly discovered peptide and an endogenous ligand for growth hormone (GH) secretagogue (GHS) receptor. It has been shown to possess various central peripheral effects, including GH secretion, food intake, gastric cardiac effects. the GHS receptor are expressed also in pancreatic islets. We have identified several ghrelin-induced genes by PCR-select subtraction methods, among which β-cell autoantigen type 1 diabetes, IA-2β. Administration of ghrelin increased IA-2β mRNA mouse...
Ghrelin inhibits insulin secretion partly via induction of IA-2beta. However, the orexigenic effect ghrelin is mediated by AMP-activated protein kinase (AMPK)-uncoupling 2 (UCP2) pathway. Here, we demonstrate that ghrelin's inhibitory on also occurs through AMPK-UCP2 increased AMPK phosphorylation and UCP2 mRNA expression in MIN6 insulinoma cells. Overexpression or downregulation attenuated enhanced secretion, respectively. Furthermore, activator had a similar to In conclusion, pathway,...
Some investigators have suggested that testicular descent relative to the ovary is actually caused by upward growth of structures adjacent testis and in early phase anchored inguinal region as embryo enlarges. This concept was founded on results from dissection human fetuses. In this study development urogenital system fetal mice examined using scanning electron microscopy determine distance between bladder neck lower pole gonad. The confirm transabdominal one sense really ascent mouse,...
OBJECTIVE—To determine genetic predispositions for diabetic polyneuropathy, we investigated the relationship between −866G/A polymorphism of uncoupling protein (UCP) 2 and neurological manifestations in 197 type patients. RESEARCH DESIGN AND METHODS—We first examined whether UCP2 mRNA had been expressed dorsal root ganglion (DRG) four Long-Evans Tokushima Otsuka rats using RT-PCR electrophoresis. Genotyping promoter was then performed unrelated Japanese patients, who were subjected to nerve...
A novel cDNA clone encoding a cytochrome P450 was screened from gut library of permethrin‐resistant Culex quinquefasciatus larvae. Nucleotide sequence the designated CYP6E1 determined. This is first full‐length mosquito cDNA. Comparison deduced amino acid to those other known P450s indicates that this belongs CYP6 family. In addition, phylogenetic analysis primary structure showed it related CYP6A and CYP6C subfamilies. Polymerase chain reaction (PCR) using primers designed on basis...
A 38-year-old woman was hospitalized in August 2007. This visit her fifth episode of acute pancreatitis. Computed tomography revealed a cystic structure located near the antrum. Communication between this and pancreatic duct by endoscopic retrograde cholangiopancreatography. Ultrasonography that cyst wall had layered structure. Thus, we regarded it as gastric duplication cyst. We thought communicating with an aberrant responsible for recurrent In 2008, gastrostomy performed stomach. No...
Laparoscopic percutaneous extraperitoneal closure (LPEC) has been widely performed for the repair of pediatric inguinal hernias in Japan. This study aimed to evaluate testicular ascent and orchiopexy after LPEC males with hernias.The medical records male patients who underwent procedures an hernia from January 2010 December 2013 at our institution were reviewed. The procedure investigated, characteristics studied birth weight patients, age when they LPEC, mean time orchiopexy, location...
Laparoscopic percutaneous extraperitoneal closure (LPEC) has been performed in Japan for the repair of pediatric inguinal hernias over a decade. However, safety and efficacy LPEC neonates infants under 1 year age remain unknown. The aim present study is to elucidate treatment hernia patients who are younger than age.The medical records underwent at Saga-Ken Medical Center Koseikan (Saga, Japan) between August 2007 November 2012 were collected. intraoperative findings postoperative outcomes...
Abstract Activation of antibacterial protein genes by various chitin oligomers (from dimer to hexamer) was investigated Northern blot analysis using cDNAs encoding cecropin B, attacin and lebocin from Bombyx mori as probes. All tested were found strongly trigger expression genes. Furthermore, gene triggered confirmed occur specifically in the fat body haemocytes. These results suggest that have same characteristics those lipopolysaccharide (LPS) peptidoglycan triggering insect proteins.
To investigate whether prenatal stress affects the pituitary-testicular axis in relation to testicular descent rat fetuses, as maternal can alter plasma testosterone concentration and inhibit male fetuses.Pregnant rats were divided into two groups kept reverse light-dark cycles, with lights-off at 08.00 hours on 20.00 hours. In group 1, 15 pregnant females placed three times daily for 60 min each session plastic rat-holders (13 x 6 8 cm) illuminated by 150-W flood lights during dark phase,...
Esophageal motility was assessed in a case of long-gap esophageal atresia (EA) without tracheoesophageal fistula before primary anastomosis, addition manometrical studies were also experimentally performed mongrel dogs to investigate the pathogenesis disorders successfully repaired EA. Coordinated peristaltic contractions observed between proximal and distal pouch when swallowing anastomosis In addition, these induced reflex relaxation lower sphincter (LES) as seen normal esophagus at age 8...