A5062302140- Functional Brain Connectivity Studies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Spatial Neglect and Hemispheric Dysfunction
- Hemispheric Asymmetry in Neuroscience
- Neural Networks and Applications
- Neuroscience and Neuropharmacology Research
- Advanced MRI Techniques and Applications
- Cardiovascular Syncope and Autonomic Disorders
- Psychological and Educational Research Studies
- Face Recognition and Perception
- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- Technology Assessment and Management
- Neurotransmitter Receptor Influence on Behavior
- Advanced Neuroimaging Techniques and Applications
Max Planck Institute for Human Cognitive and Brain Sciences
2018-2024
University of Münster
2022-2024
Max Planck Society
2018-2019
Tampere University
2018
Tampere University Hospital
2018
Abstract We present a publicly available dataset of 227 healthy participants comprising young (N=153, 25.1±3.1 years, range 20–35 45 female) and an elderly group (N=74, 67.6±4.7 59–77 37 acquired cross-sectionally in Leipzig, Germany, between 2013 2015 to study mind-body-emotion interactions. During two-day assessment, completed MRI at 3 Tesla (resting-state fMRI, quantitative T1 (MP2RAGE), T2-weighted, FLAIR, SWI/QSM, DWI) 62-channel EEG experiment rest. task-free resting-state...
While many structural and biochemical changes in the brain have previously been associated with older age, findings concerning functional properties of neuronal networks, as reflected their electrophysiological signatures, remain rather controversial.These discrepancies might arise due to several reasons, including diverse factors determining general spectral slowing alpha frequency range well amplitude mixing between rhythmic non-rhythmic parameters.We used a large dataset ( N = 1703, mean...
Variability of neural activity is regarded as a crucial feature healthy brain function, and several neuroimaging approaches have been employed to assess it noninvasively. Studies on the variability both evoked response spontaneous signals shown remarkable changes with aging but unclear if different measures signal – identified either hemodynamic or electrophysiological methods reflect same underlying physiology. In this study, we aimed explore age differences two imaging modalities (EEG,...
The heartbeat-evoked potential (HEP) is a brain response to each heartbeat, which thought reflect cardiac signaling central autonomic areas and suggested be marker of internal body awareness (eg, interoception).Because communication with circuits has been shown impaired in patients atrial fibrillation (AF), we hypothesized that HEPs are attenuated these patients.By simultaneous electroencephalography electrocardiography recordings, HEP was investigated 56 individuals persistent AF control...
Multiverse analysis has emerged as a valuable tool for increasing transparency and assessing robustness in empirical research across many scientific disciplines. By systematically exploring multiple defensible analytical paths, researchers can uncover how different decisions data processing, model specification, estimation impact results. However, while multiverse holds significant promise, it also presents several challenges that must navigate. This paper draws on interdisciplinary...
Patients with lesion to the orbitofrontal cortex (OFC) experience challenges in emotional control and emotion-guided behaviors. The OFC is known participate executive function attentional of emotion our previous research suggests alters balance between voluntary involuntary attention cognitive within context emotion. To better understand how affects dynamics interaction these functions, we studied EEG behavioral performance 12 patients 11 subjects intact a Go/NoGo visual reaction time task...
Abstract The ongoing reproducibility crisis in psychology and cognitive neuroscience has sparked increasing calls to re-evaluate reshape scientific culture practices. Heeding those calls, we have recently launched the EEGManyPipelines project as a means assess robustness of EEG research naturalistic conditions experiment with an alternative model conducting research. One hundred sixty-eight analyst teams, encompassing 396 individual researchers from 37 countries, independently analyzed same...
Abstract Neural health relies on cortical excitation–inhibition balance (EIB). Previous research suggests a link between increased excitation and neuroplasticity induced by selective serotonin reuptake inhibitors (SSRIs). Whether there are modulations of EIB following SSRI‐administration in the healthy human brain, however, remains unclear. Thus, randomized double‐blind study, we administered clinically relevant dose 20 mg escitalopram for 7 days (time when steady state is achieved) 59 women...
Aging is associated with increased white matter hyperintensities (WMHs) and alterations of alpha oscillations (7–13 Hz). However, a crucial question remains, whether changes in relate to aging per se or this relationship mediated by age-related neuropathology like WMHs. Using large cohort cognitively healthy older adults (N = 907, 60–80 years), we assessed relative power, peak frequency, long-range temporal correlations from resting-state EEG. We further these parameters voxel-wise WMHs 3T...
Abstract Much of our behaviour is driven by two motivational dimensions—approach and avoidance. These have been related to frontal hemispheric asymmetries in clinical resting‐state EEG studies: Approach was linked higher activity the left relative right hemisphere, while avoidance opposite pattern. Increased approach behaviour, specifically towards unhealthy foods, also observed obesity has asymmetry framework right‐brain hypothesis obesity. Here, we aimed replicate previous findings for...
The ongoing reproducibility crisis in psychology and cognitive neuroscience has sparked increasing calls to re-evaluate reshape scientific culture practices. Heeding those calls, we have recently launched the EEGManyPipelines project as a means assess robustness of electroencephalography (EEG) research naturalistic conditions experiment with an alternative model conducting research. 168 analyst teams, encompassing 397 individual researchers from 37 countries, independently analyzed same...
Abstract While many structural and biochemical changes in the brain have been previously associated with aging, findings concerning electrophysiological signatures, reflecting functional properties of neuronal networks, remain rather controversial. To try resolve this issue, we took advantage a large population study (N=1703) comprehensively investigated association multiple EEG biomarkers (power alpha theta oscillations, individual peak frequency (IAF), slope 1/f power spectral decay),...
Abstract Variability of neural activity is regarded as a crucial feature healthy brain function, and several neuroimaging approaches have been employed to assess it noninvasively. Studies on the variability both evoked response spontaneous signals shown remarkable changes with aging but unclear if different measures signal – identified either hemodynamic or electrophysiological methods reflect same underlying physiology. In this study, we aimed explore age differences two imaging modalities...
Abstract In the complex landscape of daily life, we continuously balance between maintaining focus despite distractions and flexibly updating when needed—a cognitive process governed by a mechanism known as working memory gating. While much research has focused on neural locus this mechanism, less is about underlying dynamics. Here probe role network excitation/inhibition (E/I) dynamics in Utilizing resting-state electroencephalography, extract two markers E/I dynamics: long-range temporal...
Abstract Aging is associated with increased white matter hyperintensities (WMHs) and the alterations of alpha oscillations (7–13 Hz). However, a crucial question remains, whether changes in relate to aging per se or this relationship mediated by age-related neuropathology like WMHs. Using large cohort cognitively healthy older adults (N=907, 60-80 years), we assessed relative power, peak frequency, long-range temporal correlations (LRTC) from resting-state EEG. We further these parameters...
Abstract Much of our behaviour is driven by two motivational dimensions – approach and avoidance. These have been related to frontal hemispheric asymmetries in clinical resting-state EEG studies: was linked higher activity the left relative right hemisphere, while avoidance opposite pattern. Increased behaviour, specifically towards unhealthy foods, also observed obesity has asymmetry framework right-brain hypothesis obesity. Here, we aimed replicate previous findings for self-reported...
Abstract Neural health relies on cortical excitation-inhibition balance (EIB), with disrupted EIB underlying circuit dysfunction in several neuropsychiatric disorders. Previous research suggests links between increased excitation and neuroplasticity induced by selective serotonin reuptake inhibitors (SSRIs). Whether there are modulations of following SSRI-administration the healthy human brain, however, remains unclear. To this end, we assessed changes longitudinal escitalopram-intake. In a...