A5102011538- Natural product bioactivities and synthesis
- NF-κB Signaling Pathways
- Immune Response and Inflammation
- Peroxisome Proliferator-Activated Receptors
- Fungal Infections and Studies
- Cardiovascular Health and Risk Factors
- Animal Nutrition and Physiology
- Cancer-related molecular mechanisms research
- Probiotics and Fermented Foods
- Immune cells in cancer
- Fatty Acid Research and Health
- Medicinal Plants and Neuroprotection
- Machine Learning in Healthcare
- Antioxidant Activity and Oxidative Stress
- Nutritional Studies and Diet
- COVID-19 diagnosis using AI
- Adenosine and Purinergic Signaling
- Cardiac pacing and defibrillation studies
- Neurofibromatosis and Schwannoma Cases
- Myasthenia Gravis and Thymoma
- Asthma and respiratory diseases
- Rheumatoid Arthritis Research and Therapies
- Salmonella and Campylobacter epidemiology
- Plant-based Medicinal Research
- IL-33, ST2, and ILC Pathways
Zhongkai University of Agriculture and Engineering
2024
Ministry of Agriculture and Rural Affairs
2024
Guangdong Academy of Agricultural Sciences
2024
Jiaxing University
2020-2024
Fujian Provincial Hospital
2020-2021
Fujian Medical University
2020-2021
Hypertension Institute
2019
People's Hospital of Xinjiang Uygur Autonomous Region
2018
China Pharmaceutical University
2008-2012
Albany College of Pharmacy and Health Sciences
2012
In a population-based case-control study of colorectal cancer among Chinese men and women in western North America the People's Republic China, common protocol was used to assess past life-style characteristics 905 cases diagnosed during 1981–1986 2,488 controls. Risks for cancers both colon rectum increased with food energy from fat, protein, carbohydrate, all sources combined, sexes on continents. Yet, multivariate analysis, risk significantly associated only saturated fat; no...
We tested the hypothesis that food deprivation alters body temperature (T b ) responses to bacterial LPS by enhancing inflammatory signaling decreases T (cryogenic signaling) rather than suppressing increases (febrigenic signaling). Free-feeding or food-deprived (24 h) rats received at doses (500 and 2,500 μg/kg iv) are high enough activate both febrigenic cryogenic signaling. At these doses, caused fever in an ambient of 30°C, but produced hypothermia 22°C. Whereas had little effect on...
The P2X4 receptor is a newly identified expressed in the heart cell. Its function was elucidated with cardiac transgenic (TG) expression of by using myocardium-specific a-myosin heavy chain promoter. presence transgene determined polymerase reaction primers specific to and vector linker region, Southern blotting genomic DNA, immunoblotting immunohistochemistry both isolated myocytes intact hearts. In study, TG mouse exhibited significantly elevated basal contractility greater rates...
MitoTEMPO, a mitochondrial antioxidant, has protective effects on liver-related diseases. However, the role of MitoTEMPO nonalcoholic fatty liver disease (NAFLD) and its possible mechanisms are largely unknown. Here, we investigated NAFLD using high fat diet- (HFD-) induced obese mice as animal models. was intraperitoneally injected into HFD mice. Liver morphological changes were observed by H&E Oil Red O staining, frequency MDSCs in peripheral blood analyzed flow cytometry. Moreover,...
Objective: To investigate the current status of diagnosis and treatment pulmonary cryptococcosis in respiratory medicine improve understanding clinical characteristics HIV-negative China. Methods: A prospective multi-center open cohort study was designed to screen for general wards intensive care units Department Respiratory Diseases 22 hospitals. The patients with positive cryptococcal etiological based on smear culture, antigen detection histopathology were enrolled study. data collected...
A phytochemical investigation of the anomalous fruits Gleditisia sinensis led to one new oleanane-type triterpenoid saponin acylated with monoterpenic acid, 3-O-beta-D-glucopyranosyl oleanolic acid 28-O-beta-D-xylopyranosyl-(1 --> 3)-beta-D-xylopyranosyl-(1 4)-alpha-L-rhamnopyranosyl-(1 2)-[(6S,2E)-6-hydroxy-2,6-dimethyl-2,7-octadienoyl-(1 6)]-beta-D-glucopyranosyl ester, named gleditsioside Z (1), together nine known ones (2-10). Their structural details were mainly established on basis 1D,...
Lung adenocarcinoma (LUAD) is a life-threatening disease worldwide with high mortality rate. The early diagnosis of LUAD crucial for improving subsequent treatment and prognosis. However, biomarkers detection remain clinical challenge in LUAD. Here, we aimed to develop circular RNAs (circRNAs) circulating plasma from patients as valuable diagnostic LUAD.CircRNA expression was determined by circRNA microarray three pairs tumour tissues patient-matched normal lung tissues. Hsa_circ_101555...
The case of a patient with type B3 thymomacomorbid <em>Chlamydia</em> <em>psittaci</em> (<em>C</em>. <em>psittaci</em>) pneumonia exhibiting rare features is presented in the current report. was admitted at Second Affiliated Hospital Jiaxing University (Jiaxing, China) history direct contact poultry. Clinical manifestations included fever, shivers, cough, fatigue and poor appetite. Chest computed tomography (CT) indicated right lung pneumonia, while metagenomics next‑generation sequencing...
Salmonella typhimurium is a common cause of gastroenteritis, which infects animals and human. Protocatechuic acid has anti-inflammatory, immunoregulatory anti-pathogenic effects, expected to be an effective choice for alleviating infection intestinal injury. A total 180 1-d female, yellow-feathered chickens were randomly allocated into 3 treatment groups, the controls (Ctr), Salmonella-challenged (Sal) protocatechuic (PA). Birds fed basal diet 18 d, with birds in PA supplemented 600 mg/kg...
Dietary lysine and apparent nitrogen-corrected metabolizable energy (AMEn) are two key variables affecting the production of breeder hens. In this study, effects interactions AMEn on yellow-feathered broiler hens were investigated. A total 720 30-week-old fed in a 5 (lysine: 0.56%, 0.68%, 0.80%, 0.92%, 1.04%) × 2 (AMEn: 11.50 11.10 MJ/kg) factorial arrangement for 12 weeks. The productive performance, reproductive traits, biochemical hens, amino acid concentration quality eggs, growth...
ABSTRACT We previously reported that splenic extract from lipopolysaccharide (LPS)‐challenged guinea pigs inhibits the exaggerated febrile response of splenectomized pigs, suggesting spleen generates an inhibitory factor. Earlier results indicate factor is a lipid. In effort to identify this factor, lipid fractions, isolated extracts control and LPS‐challenged were analyzed with emphasis on identifying quantifying prostanoids, which according current knowledge are likely bioactive factors....
Abstract Objective This study aimed to summarize the characteristics of chest CT imaging in Chinese patients with Coronavirus Disease 2019 (COVID-19) provide reliable evidence for further guiding clinical routine. Methods PubMed, Embase and Web Science databases were thoroughly searched identified relevant articles involving features COVID-19. All data analyzed utilizing R software version i386 4.0.0. Random-effects models employed calculate pooled mean differences. Results 19 trials...
Objective: Hypertension is common worldwide. Patterns of hypertension may vary in remote less developed areas. Xinjiang Northwest China a multi-ethnic province with low income, education and medical resource-constriction background, where affecting up to 54.6% adults 30 years older, characterized by lower treatment control rates higher prevalence mortality stroke. Therefore, we selected Emin county, typical above condition, implement government-expert joint comprehensive intervention for...
Objective: Prevalence of hypertension in Xinjiang, Northwest China is approximately 30–54.6% population aged 30 years and older, ranks at the national forefront due to its geographical remoteness, unhealthy eating habits, physical inactivity, whereas treatment control rates are too low for several reasons, which encompass a relatively backward economy (GDP ranking 25th among 31 provinces by 2014), extremely premature medical conditions (), lower educational level (illiteracy rate: about 19%,...
Objective: Hypertension and diabetes are high risk groups in patients with OSA, moderate or severe OSA often leads to poorly controlled fasting blood glucose pressure. Postmenopausal women have increased incidence of cardiovascular disease diabetes, anxiety, depression, sleep disorders. However, the clinical symptoms female population not typical, relationship between mellitus is less concerned. To investigate effect on parameters postmenopausal by comparing nocturnol parameter menopausal...