A5043575760- Neuroscience and Neural Engineering
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Neurological disorders and treatments
- Dendrimers and Hyperbranched Polymers
- Advanced X-ray and CT Imaging
- Conducting polymers and applications
- Bone Tissue Engineering Materials
- Photoreceptor and optogenetics research
- Advanced Chemical Sensor Technologies
- Orthopaedic implants and arthroplasty
- Nerve injury and regeneration
- Parkinson's Disease Mechanisms and Treatments
- SARS-CoV-2 and COVID-19 Research
- Porphyrin and Phthalocyanine Chemistry
- Advanced materials and composites
- Photochemistry and Electron Transfer Studies
- Photopolymerization techniques and applications
- Anesthesia and Neurotoxicity Research
- Aluminum Alloys Composites Properties
- MXene and MAX Phase Materials
- Polymer Surface Interaction Studies
- Surface Roughness and Optical Measurements
- Ion channel regulation and function
Fraunhofer USA
2021-2025
Michigan State University
2022-2025
University of Arizona
2020-2023
Abstract With the advantages of superior energy density, lithium‐sulfur batteries (LSBs) have been considered as one promising next‐generation batteries. However, some key issues, such shuttle effect intermediate lithium polysulfides, poor conductivity sulfur, Li 2 S and , huge volume variation during charge/discharge process, hindered its development. In this respect, a variety nanomaterials used to overcome above‐mentioned defects. Among them, two‐dimensional (2D) present unique merits for...
Abstract Fast‐scan cyclic voltammetry (FSCV) is a popular approach for real‐time neurochemical sensing. Using carbon‐fiber microelectrode (CFME), sensitive sensing can be achieved in the acute setting with sub‐second resolution monoamine neurotransmitters. However, to study neuropsychiatric conditions and neurological functions, it often of interest perform longitudinal monitoring neurotransmitters over chronic timepoints. Despite notable successes, there remains substantial room improvement...
Neurotransmitter release is important to study in order better understand neurological diseases and treatment approaches. Serotonin a neurotransmitter known play key roles the etiology of neuropsychiatric disorders. Fast-scan cyclic voltammetry (FSCV) has enabled detection neurochemicals, including serotonin, on sub-second timescale via well-established carbon fiber microelectrode (CFME). However, poor chronic stability biofouling, i.e., adsorption interferent proteins electrode surface upon...
3D printed biomaterial implants are revolutionizing personalized medicine for tissue repair, especially in orthopedics. In this study, a radiopaque bismuth oxide (Bi
Abstract Neuromodulation technologies have gained considerable attention for their clinical potential in treating neurological disorders and advancing cognition research. However, traditional methods like electrical stimulation optogenetics face technical biological challenges that limit therapeutic research applications. A promising alternative, photoelectric neurostimulation, uses near‐infrared light to generate pulses thus enables of neuronal activity without genetic alterations. This...
Fast-scan cyclic voltammetry (FSCV) is an electrochemical sensing technique that can be used for neurochemical with high spatiotemporal resolution. Carbon fiber microelectrodes (CFMEs) are traditionally as FSCV sensors. However, CFMEs prone to fouling caused by oxidative byproducts of repeated serotonin (5-HT) exposure, which makes them less suitable chronic 5-HT Our team developing a boron-doped diamond microelectrode (BDDME) has previously been shown relatively resistant protein adsorption...
Abstract Objective Neuromodulation technologies have gained considerable attention for its clinical potential in treating neurological disorders and their capacity to advance cognition research. Nevertheless, traditional neuromodulation methods such as electrical stimulation optogenetics manipulation currently experience technical biological challenges that hinge therapeutic chronic research applications. Recently, a promising alternative approach based on the photoelectric effect has...
Fast-scan cyclic voltammetry (FSCV) is an electrochemical sensing technique that can be used for neurochemical with high spatiotemporal resolution. Carbon fiber microelectrodes (CFMEs) are traditionally as FSCV sensors. However, CFMEs prone to fouling caused by oxidative byproducts of repeated serotonin (5-HT) exposure, which makes them less suitable a chronic 5-HT sensor. Our team developing boron-doped diamond microelectrode (BDDME) has previously been shown relatively resistant protein...
Carbon-fiber microelectrodes allow for high spatial and temporal measurements of electroactive neurotransmitter in vivo using fast-scan cyclic voltammetry (FSCV). However, common instrumentation such systems lack patient safety precautions. To add precautions as well to overcome chemical electrical noise, a two-electrode FSCV headstage was modified introduce an active bandpass filter on the electrode side measurement amplifier. This modification reduced measured noise ac-coupled voltammetric...
Technologies capable of detecting changes in neurochemical signals can be used to understand the underlying mechanisms neurological diseases. They are also important components systems which rely on sensing as a source feedback for closed-loop neuromodulation[1], [2]. Recently, our research team has developed boron-doped diamond microelectrode (BDDME) fiber neurotransmitter detection using fast-scan cyclic voltammetry (FSCV). These electrodes have several potential benefits comparison more...
ABSTRACT 3D printed biomaterial implants are revolutionizing personalized medicine for tissue repair, especially in orthopedics. In this study, a radiopaque Bi 2 O 3 doped polycaprolactone ( PCL ) composite is developed and implemented to enable the use of diagnostic X-ray technologies, photon counting computed tomography PCCT ), comprehensive vivo device monitoring. filament with homogeneous nanoparticle NP dispersion (0.8 11.7 wt%) first fabricated. Tissue engineered scaffolds TES then...
Many requirements and applications in various industrial sectors demand high-quality finishes on parts. These finishes, whether due to tolerances or surface quality, are often challenging achieve through additive manufacturing technologies, necessitating additional post-processing. This study aims investigate the effect of specific treatments parts produced Sintering Based Additive Manufacturing (SBAM), such as Fused Filament Fabrication (FFF). With premise employing affordable...
Neurochemical sensing with implantable devices has gained remarkable attention over the last few decades. A promising area of this research is progress novel electrodes as electrochemical tools for neurotransmitter detection in brain. The boron-doped diamond (BDD) electrode one such candidate that previously been reported its excellent properties, including a wide working potential, superior chemical inertness and mechanical stability, good biocompatibility resistance to fouling. Meanwhile,...
Levels of the opioid peptide dynorphin, an endogenous ligand selective for kappa-opioid receptors (KORs), its mRNA and pro-peptide precursors are differentially dysregulated in Parkinson disease (PD) following development L-DOPA-induced dyskinesia (LID). It remains unclear, whether these alterations contribute to pathophysiological mechanisms underlying PD motor impairment subsequent LID, or they part compensatory mechanisms. We sought investigate nor-BNI, a KOR antagonist, 1) dopamine...
Analysis of trace level metals in environmental samples (e.g., soil, water, and plant samples) is important for assessing quality food safety. This paper reports a non-toxic, eco-friendly, cost-effective sensing method, capable in-situ detection microgram per liter (µg/L) levels heavy metal ions soil solutions using carbon fiber electrodes (CFEs) produced without any microfabrication. The electrochemical behaviors the CFEs were characterized by cyclic voltammetry (CV) impedance spectroscopy...