A5013458083- Gut microbiota and health
- Tryptophan and brain disorders
- Health, psychology, and well-being
- Indoor Air Quality and Microbial Exposure
- Climate Change and Health Impacts
- Traumatic Brain Injury Research
- Noise Effects and Management
- Toxoplasma gondii Research Studies
- Dermatology and Skin Diseases
- Cardiac Arrest and Resuscitation
- Air Quality and Health Impacts
- Traumatic Brain Injury and Neurovascular Disturbances
- Intensive Care Unit Cognitive Disorders
- Food Security and Health in Diverse Populations
- Diet and metabolism studies
- Urban Green Space and Health
- Homelessness and Social Issues
- Innovations in Concrete and Construction Materials
- Cytomegalovirus and herpesvirus research
- Resilience and Mental Health
- BIM and Construction Integration
- Human-Animal Interaction Studies
- Spaceflight effects on biology
- Palliative Care and End-of-Life Issues
- Construction Project Management and Performance
U.S. Air Force Institute of Technology
2018-2024
University of Colorado Anschutz Medical Campus
2020-2024
Mental Illness Research, Education and Clinical Centers
2016-2024
Wright-Patterson Air Force Base
2019-2024
Veterans Health Administration
2019-2024
VA Rocky Mountain Network
2019-2023
Lowry Memorial College & Group of Institutions
2017-2020
United States Air Force Academy
2015-2017
The University of Texas at Austin
2013-2014
Inadequate immunoregulation and elevated inflammation may be risk factors for posttraumatic stress disorder (PTSD), microbial inputs are important determinants of immunoregulation; however, the association between gut microbiota PTSD is unknown. This study investigated microbiome in a South African sample PTSD-affected individuals trauma-exposed (TE) controls to identify potential differences diversity or community structure.The Clinician-Administered Scale DSM-5 was used diagnose according...
Most people spend the majority of their lives indoors. Research over last thirty years has focused on investigating mechanisms through which specific elements built environment, such as indoor air quality, influence physical health occupants. However, similar effort not been expended in regard to mental health, a significant public concern. One five Americans diagnosed with disorder past year, and, United States, number suicide deaths are due breast cancer. Increases disorders Western...
Background: US military Veterans returned from Operation Enduring Freedom/Operation Iraqi New Dawn (OEF/OIF/OND) with symptoms associated mild traumatic brain injury [mTBI; i.e., persistent post-concussive (PPC) symptoms] and posttraumatic stress disorder (PTSD). Interventions aimed at addressing both physical psychological stressors (e.g., PPC PTSD symptoms) are needed. This study was conducted to assess the feasibility, acceptability, safety of a probiotic intervention, as well begin...
Injuries and subclinical effects from exposure to blasts are of significant concern in military operational settings, including tactical training, associated with self-reported concussion-like symptomology physiological changes such as increased intestinal permeability (IP), which was investigated this study. Time-series gene expression IP biomarker data were generated “breachers” exposed controlled, low-level explosive blast during training. Samples 30 male participants at pre-, post-,...
The microbiome of the built environment has important implications for human health and wellbeing; however, bidirectional exchange microbes between occupants surfaces can be confounded by lifestyle, architecture, external environmental exposures. Here, we present a longitudinal study United States Air Force Academy cadets (n = 34), which have substantial homogeneity in diet, age, all factors that influence microbiome. We characterized bacterial communities associated with (1) skin gut...
Compared to microbiomes on other skin sites, the bacterial microbiome of human hand has been found have greater variability across time. To increase understanding regarding longitudinal transfer objects in built environment, and vice versa, 22 participants provided samples from their dominant hands, as well frequently infrequently touched office environments. Additional home environments were obtained a subset 11 participants. We observed stability both within settings; however, differences...
The purpose of this study was to evaluate the influence a new course antidepressant monotherapy on gut and oral microbiomes relationship depressive symptoms.
The microorganisms present in retail environments have not been studied detail despite the fact that these represent a potentially important location for exposure. In this study, HVAC filter dust samples 13 US stores were collected and analyzed via pyrosequencing to characterize indoor bacterial communities explore potential relationships between building environmental parameters. Although contained diverse community of 788 unique genera, over half nearly 118K sequences attributed...
Several studies have reported an association between nonceliac gluten sensitivity and schizophrenia. Immune kynurenine (KYN) pathways also been implicated in the pathophysiology of schizophrenia, certain proinflammatory immune mediators may increase KYN reduce tryptophan (TRP) levels.We measured serum antigliadin immunoglobulin G (IgG), KYN, TRP 950 patients with Patients antibody level at 90th percentile or higher control participants (21.9% all patients) were classified as having elevated...
Objective: To evaluate the association between distal moderate/severe traumatic brain injury (TBI) history and human gut microbiome. Setting: Veterans Affairs Medical Center. Participants: from United States-Veteran Microbiome Project (US-VMP). with TBI ( n = 34) were compared (1) a of no 79) (2) or mild only 297). Design: analyses 16S rRNA gene sequencing microbiota function inferred using PICRUSt2. Main Measures: α-Diversity β-diversity microbiome, as well taxonomic functional signatures...
Injuries from exposure to blasts are of significant concern in military operational settings, including tactical training, and is associated with self-reported concussion-like symptomology physiological changes as increased intestinal permeability (IP) investigated herein. Timeseries gene expression IP biomarker data were generated “breachers” exposed controlled, low-level explosive blast during training. Samples 30 male participants at pre, post, follow-up the next day...
Abstract Recent microbiome research has incorporated a higher number of samples through more participants in study, longitudinal studies, and metanalysis between studies. Physical limitations sequencing machine can result spread across runs. Here we present the results nearly 1000 16S rRNA gene sequences fecal (stabilized swab) oral (swab) from multiple human studies positive controls that were conducted with identical standard operating procedures. Sequencing was performed same center 18...
Significant effort has been put forth to increase understanding regarding the role of human microbiome in health- and disease-related processes. In turn, United States (US) Veteran Microbiome Project (US-VMP) was conceptualized as a means by which serially collect health-related data from those seeking care within Veterans Health Administration (VHA). this manuscript, exposures related military experiences, well conditions factors among patients seen VHA clinical settings are discussed...