- Gut microbiota and health
- Cellular transport and secretion
- Salivary Gland Disorders and Functions
- Oral microbiology and periodontitis research
- Pediatric health and respiratory diseases
- Biochemical and Structural Characterization
- Neurotransmitter Receptor Influence on Behavior
- Birth, Development, and Health
- Spaceflight effects on biology
- Dental Health and Care Utilization
- Genetics, Aging, and Longevity in Model Organisms
- Tryptophan and brain disorders
- Health, psychology, and well-being
- Genetic Associations and Epidemiology
- Endoplasmic Reticulum Stress and Disease
- Microtubule and mitosis dynamics
- Substance Abuse Treatment and Outcomes
- Lipid Membrane Structure and Behavior
University of Colorado Boulder
2015-2019
Stanford University
2019
Lowry Memorial College & Group of Institutions
2017
Inadequate immunoregulation and elevated inflammation may be risk factors for posttraumatic stress disorder (PTSD), microbial inputs are important determinants of immunoregulation; however, the association between gut microbiota PTSD is unknown. This study investigated microbiome in a South African sample PTSD-affected individuals trauma-exposed (TE) controls to identify potential differences diversity or community structure.The Clinician-Administered Scale DSM-5 was used diagnose according...
The human oral microbiome is formed early in development. Its composition influenced by environmental factors including diet, substance use, health, and overall health disease. influence of genes on the stability still poorly understood. We studied both genetic characteristics a large twin sample as well cohort unrelated individuals. identify several significantly heritable features microbiome. heritability persists twins even when their cohabitation changes. these traits correlates with...
Significance Rab GTPases are central regulators of vesicle-mediated cargo transport. They switched from the GDP-bound inactive conformation to GTP-bound active state by guanine nucleotide exchange factors (GEFs). Rab-interacting factor (RABIF)/mammalian suppressor Sec4 (MSS4) and its yeast homolog DSS4 first putative GEFs isolated for Rabs, but their biological function molecular mechanism remained unclear. In this work, we demonstrate that RABIF plays a crucial role in exocytosis....