A5102793214- Epigenetics and DNA Methylation
- Ocular Oncology and Treatments
- Meningioma and schwannoma management
- Nerve injury and regeneration
- Cancer and Skin Lesions
- Skin Protection and Aging
- Nonmelanoma Skin Cancer Studies
- Proteoglycans and glycosaminoglycans research
- Blood disorders and treatments
- Histone Deacetylase Inhibitors Research
- Ear and Head Tumors
- Dermatology and Skin Diseases
- Reconstructive Surgery and Microvascular Techniques
- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Hedgehog Signaling Pathway Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pharmacological Effects and Toxicity Studies
- Asthma and respiratory diseases
- Olfactory and Sensory Function Studies
- Vascular Malformations and Hemangiomas
- Renal function and acid-base balance
- Acute Myeloid Leukemia Research
- S100 Proteins and Annexins
- HER2/EGFR in Cancer Research
Washington University in St. Louis
2011-2023
Banyan Biomarkers (United States)
2011
Orlando Regional Medical Center
2011
Flinders University
2002-2008
University of California, San Diego
2002
Nambour General Hospital
1993
Valley Hospital
1980
National Measurement Laboratory
1980
The Alfred Hospital
1973
Arthritis and Rheumatism Associates
1960
Abstract Importance Identifying risk factors for radiation‐induced optic neuropathy (RION) could promote a more conservative approach to radiation treatment planning in vulnerable patients. Background This study explored possible beyond dose associated with the development of RION after external beam therapy. Design was retrospective case–control conducted at university hospital tertiary care center. Participants Cases ( n = 14) meeting criteria diagnosis by neuro‐ophthalmologic exam were...
Significance Keratinocyte carcinomas are the most common malignancies in fair-skinned patients. Increased age and sun exposure important skin cancer risk factors have been associated with a loss of DNA methylation human epidermis. Complete Dnmt3a deficiency mouse creates premalignant state, but mechanisms responsible for this phenomenon not clear. This study demonstrates that murine epidermis causes focal, canonical hypomethylation an increased proportion cells proliferative gene expression...
Radiation optic neuropathy (RON) is a rare complication of external beam radiation therapy (RT) in which exposure the anterior visual pathway (AVP) to results acute, painless vision loss one or both eyes, months years after treatment (1). The diagnosis RON supported by constant enhancement on MRI an involved area previous without evidence tumor involvement. No has proven effective reversing this loss; therefore management individualized. Maximum dose apparatus most significant known risk...
Although previously reported immunologic complications from immune checkpoint blockade have been autoimmune, we report a case of disseminated blastomycosis infection in the setting pembrolizumab therapy. This unexpected infectious complication confounded monitoring our patient's metastatic melanoma and had important consequences for his continued cancer A healthy 77-year-old man presented to primary care physician Missouri with new right axillary mass. Computed tomography (CT) found an...
The potencies of six commerically manufactured heparins have been measured by the British Pharmacopoeial (BP) assay and activated partial thromboplastin time (APTT), protamine sulphate, anti-Xa assays.The APTT/BP potency ratios were found to vary with preparation but this was not dependent on tissue source heparin.For mucosal heparins, anti-Xa/BP close unity, for heparin lung origin approximately one-quarter BP potency.Four fractions prepared column gel chromato- graphy a commerical...
Round maintained the clinical tradition established by predecessors, and consisted of presentation eight patients who suffered either from a rare rheumatic complaint or had been referred to Hospital with an unusual ofa condition.The was both lively witty acknowledged Society hearty applause.
A case of bilateral cervical ribs and subclavian aneurysms is presented. The genesis the vascular symptoms discussed, a technique for reconstruction artery described.
Washington University School of Medicine, St. Louis, Missouri The authors have indicated no significant interest with commercial supporters.