A5044874382- Ocular Diseases and Behçet’s Syndrome
- Cerebral Venous Sinus Thrombosis
- Retinal and Optic Conditions
- Peripheral Neuropathies and Disorders
- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Meningioma and schwannoma management
- Retinal Imaging and Analysis
- Migraine and Headache Studies
- Multiple Sclerosis Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Ocular Oncology and Treatments
- Chronic Lymphocytic Leukemia Research
- Vasculitis and related conditions
- Alcoholism and Thiamine Deficiency
- Retinal Diseases and Treatments
- Employment and Welfare Studies
- IgG4-Related and Inflammatory Diseases
- Child Abuse and Related Trauma
- Cerebrovascular and genetic disorders
- Ophthalmology and Visual Health Research
- Retinopathy of Prematurity Studies
- Facial Trauma and Fracture Management
- Autoimmune Neurological Disorders and Treatments
Washington University in St. Louis
2013-2024
Mayo Clinic
2020
University of Minnesota
2020
Prevent Blindness
2019
Scripps Clinic
2019
Wayne State University
2003-2008
Kresge Eye Institute
2004-2008
Myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG) associated disorder (MOGAD) often manifests with recurrent CNS demyelinating attacks. The optimal treatment for reducing relapses is unknown. To help determine the efficacy of long-term immunotherapy in preventing relapse patients MOGAD, we conducted a multicenter retrospective study to rate on various treatments.
The study purpose was to examine vision-specific and overall health-related quality of life (QOL) at baseline in Idiopathic Intracranial Hypertension Treatment Trial patients who were newly diagnosed had mild visual loss. We also sought determine the associations between QOL scores symptoms, function, pain, headache-related disability, obesity.
<h3>Objectives:</h3> Determine potential risk factors for progressive visual field loss in the Idiopathic Intracranial Hypertension Treatment Trial, a randomized placebo-controlled trial of acetazolamide patients with idiopathic intracranial hypertension and mild concurrently receiving low sodium, weight reduction diet. <h3>Methods:</h3> Logistic regression classification tree analyses were used to evaluate protocol-defined treatment failure (>2 dB perimetric mean deviation [PMD] change...
Patients with severe visual loss because of optic neuritis refractory to high dose corticosteroids have limited therapeutic options. The use intravenous immunoglobulin (IVIG) has been advocated in the past, but data are scarce. In this study, we a protocol different from those used other studies, timing and dosage.Consecutive patients corticosteroid-refractive neuropathy were treated IVIG compared control who received only an open-label, non-randomized, controlled prospective...
Objective: To compare serum B-cell activating factor (BAFF) levels in patients with myasthenia gravis (MG) those control subjects without MG.Design: Case-control study.Subjects: Forty-three MG were compared MG.These included 48 healthy subjects, 25 multiple sclerosis, and 3 amyotrophic lateral sclerosis.Results: In all studied, there was no correlation between the BAFF level concentration of total IgG, IgA, or IgM.The sclerosis not significantly different from subjects.However, higher than...
Abstract Importance Identifying risk factors for radiation‐induced optic neuropathy (RION) could promote a more conservative approach to radiation treatment planning in vulnerable patients. Background This study explored possible beyond dose associated with the development of RION after external beam therapy. Design was retrospective case–control conducted at university hospital tertiary care center. Participants Cases ( n = 14) meeting criteria diagnosis by neuro‐ophthalmologic exam were...
Optic disc edema is a feature of many ophthalmic and neurologic conditions. It remains an underappreciated birdshot chorioretinitis (BSCR), leading to delay in diagnosis treatment. The purpose our study was identify clinical features that are concomitant with optic suggest BSCR.
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but the majority cases are idiopathic. Myelin oligodendrocyte glycoprotein (MOG)-IgG-positive optic neuritis has been reported to associated with nerve sheath enhancement. This report describes two MOG-IgG patients clinical, radiological therapeutic response consistent perineuritis. may account for many previously described idiopathic Vision loss enhancement on MRI should prompt testing MOG-IgG.
<h3>BACKGROUND AND PURPOSE:</h3> Changes at the optic nerve head on DWI in presence of papilledema have not been systematically studied. The purpose this study was to evaluate if hyperintensity ON heads is associated with papilledema. <h3>MATERIALS METHODS:</h3> In retrospective study, 19 patients (4 men, 15 women; median age, 32 years) and 20 control participants (7 13 48 who had undergone prior MR imaging brain were identified. Two neuroradiologists blinded diagnosis independently reviewed...
Introduction We propose a minimum data set framework for the acquisition and analysis of retinal images development Alzheimer's disease (AD) biomarkers. Our goal is to describe methodology that will increase concordance across laboratories, so broader research community able cross-validate findings in parallel, accumulate large databases with normative cognitive aging spectrum, progress application this technology from discovery stage validation search sensitive specific biomarkers AD....
At times, there is a clinical need for using routine brain MR imaging performed close to the time of onset patients' visual symptoms firmly establish diagnosis optic neuritis. Our aim was assess diagnostic performance radiologists in detecting neuritis on images and whether this could be enhanced postprocessing algorithm.In retrospective case-control study 60 patients (37 women, 23 men; mean age, 47.2 [SD, 17.9] years), 2 blinded neuroradiologists evaluated T2-weighted FLAIR...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Ophthalmology HomeNew OnlineCurrent IssueFor Authors Podcast Publications Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...
Objectives.—To determine the relationship between levels of ouabain‐like compounds (OLC) in cerebrospinal fluid (CSF) and occurence idiopathic intracranial hypertension (IIH). Background.—OLC are naturally occurring inhibitors sodium‐potassium ATPase that found CSF mammals. Since production is dependent upon activity, since there evidence increased pressure condition IIH may be result production, we hypothesized level endogenous OLC would reduced patients with IIH. Methods.—CSF samples were...
A 15-week pregnant 21-year-old woman initially presented with nausea, vomiting, and abdominal pain. The patient admitted to decreased oral intake over the past 4 weeks, including her prescribed prenatal vitamins. She was hypokalemic elevated transaminases gallstone pancreatitis confirmed by imaging. Prior cholecystectomy, fetal heart tones were lost intrauterine demise occurred. underwent dilation evacuation as well cholecystectomy. discharged home but returned within 1 week persistent...
Idiopathic Intracranial Hypertension (IIH) is a condition in which patients have elevated intracranial pressure does not an apparent cause. To diagnose IIH, evaluation excluding other causes of must be performed. This typically includes magnetic resonance imaging (MRI) the brain and venous sinuses. Despite there being known radiographic signs suggestive IIH on MRI, currently are no established correlations between findings visual outcomes. Previous work revealed diffusion weighted (DWI),...
To describe two patients with anti-HMGCR antibodies, who developed limb-girdle and bulbar weakness, ophthalmoparesis.
To increase awareness of an uncommon diagnosis by detailing the clinical and radiographic characteristics isolated trochlear nerve schwannomas (TNS).
Introduction: As the population ages, increasing prevalence of neurodegenerative diseases will have profound implications for health care system. Recognizing visual symptoms from can be challenging, especially in presence co-existing eye diseases. Methods: A seven-question survey was completed by attendees at "neurodegenerative neuro-ophthalmology" symposium during 2017 North American Neuro-ophthalmology Society annual meeting using a web-based audience response Content included...
Ahealthywoman in her 50s presented to the emergency departmentwith a severe headache for 2 days. Head computed tomography findings were negative and following day, subsided. Soon thereafter, she was noted bemore forgetful unsteady. She seen by an otolaryngologist left-sided hearing loss diagnosed as having Meniere disease. Symptoms mildly abated with meclizine hydrochloride brief course of steroids. After treatment, continued decline neurologically. Subsequently, brain magnetic resonance...