A5019903155- Venomous Animal Envenomation and Studies
- Antimicrobial Peptides and Activities
- Lipid Membrane Structure and Behavior
- Biochemical and Structural Characterization
- Probiotics and Fermented Foods
- Cancer Cells and Metastasis
- Urban Transport Systems Analysis
- 3D Printing in Biomedical Research
- Ion channel regulation and function
- BIM and Construction Integration
- Logistics and Infrastructure Analysis
- Risk and Safety Analysis
- Amphibian and Reptile Biology
- Insect and Pesticide Research
- Architecture and Computational Design
- Gut microbiota and health
- Clostridium difficile and Clostridium perfringens research
- Design Education and Practice
- Rabies epidemiology and control
- Viral Infectious Diseases and Gene Expression in Insects
Universidade de São Paulo
2024
Centro Universitário do Norte Paulista
2023
Instituto Butantan
2014-2023
Universidade Federal de Juiz de Fora
2018
Crotamine is one of the main constituents venom South American rattlesnake Crotalus durissus terrificus. A common gene ancestry and structural similarity with antimicrobial β-defensins (identical disulfide bond pattern highly positive net charge) suggested potential activities for this snake toxin. Although crotamine demonstrated low activity against both Gram-positive Gram-negative bacteria, a pronounced antifungal was observed Candida spp., Trichosporon Cryptococcus neoformans. Crotamine's...
The investigation of venoms has many clinical, pharmacological, ecological and evolutionary outcomes. Crotalus spp. venom can cause hemorrhage, neurotoxicity, myotoxicity, coagulopathy hypotension. Although neurotoxicity hemorrhage usually does not occur for the same species, rare Venezuelan species vegrandis presents both characteristic. Different from other it a restricted niche geographical distribution. Nevertheless, raising medical importance as this rattlesnake population is...
The monolayer (two-dimensional or 2D) cell culture, while widely used, lacks fidelity in replicating vital interactions seen vivo, leading to a shift toward three-dimensional (3D) models. Although monolayers offer simplicity and cost-effectiveness, spheroids mimic cellular environments better. This is due its nutrient gradients, which influence drug penetration provide more accurate reflection of clinical scenarios than monolayers. Consequently, 3D models are crucial development, especially...
As transformações da sociedade proporcionadas pela tecnologia digital nos impelem a estudar suas implicações no campo arquitetura. Há algumas décadas, nota-se o impacto adoção do desenho auxiliado por computador que diz respeito à apresentação e representação de projetos, sendo que, últimos tempos, as ferramentas digitais tem assumido cada vez mais um papel ativo processo projeto. BIM, parametrização sistemas generativos são temas ligados esta transformação ainda podem ser explorados cenário...
Studies on the interactions between intestinal microbiome and its host have strengthened in last decade. However, publications this topic dogs still need to be made available, reinforcing for new studies literary data consultation. Given this, review aims describe with canine host, which can contribute both health morbid conditions these animals. The definition of encompasses collective genome all microorganisms that live a defined habitat (intestine). It is known dog’s microbiota varied,...