A5065346178- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Parathyroid Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Renal Transplantation Outcomes and Treatments
- Central Venous Catheters and Hemodialysis
- Renal and Vascular Pathologies
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Body Composition Measurement Techniques
- Diabetes Treatment and Management
- Muscle and Compartmental Disorders
- Potassium and Related Disorders
- Pharmacological Effects and Toxicity Studies
- Hemodynamic Monitoring and Therapy
- Organ Donation and Transplantation
- Vitamin D Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Hematological disorders and diagnostics
- Neurological and metabolic disorders
- Neurological Complications and Syndromes
- Cardiovascular Function and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Failure Treatment and Management
- Organ Transplantation Techniques and Outcomes
Ege University
2014-2024
Ege Üniversitesi Tıp Fakültesi Hastanesi
2024
Turkish Society of Hematology
2023
Pediatric Nephrology of Alabama
2007-2015
University of Turin
2012
Emory University
2011
University Medical Center Utrecht
2011
Okayama University
2007
Amsterdam UMC Location University of Amsterdam
2007
University of Thessaly
2007
Online haemodiafiltration (OL-HDF) is considered to confer clinical benefits over haemodialysis (HD) in terms of solute removal patients undergoing maintenance HD. The aim this study was compare postdilution OL-HDF and high-flux HD morbidity mortality. In prospective, randomized, controlled trial, we enrolled 782 thrice-weekly randomly assigned them a 1:1 ratio either or mean age 56.5 ± 13.9 years, time on 57.9 44.6 months with diabetes incidence 34.7%. follow-up period 2 the 22.7 10.9...
Most haemodialysis (HD) centres use anti-hypertensive drugs for the management of hypertension, whereas some apply dietary salt restriction strategy. In this retrospective cross-sectional study, we assessed effectiveness and cardiac consequences these two strategies.We enrolled all patients from dialysis centres, who had been on a standard HD programme at same centre least 1 year. All underwent echocardiographic evaluation. Clinical data were obtained patients' charts. Centre A (n = 190)...
We analysed the survival of 218 patients (132 male, 86 female, age 48 +/- 15 years) who were treated in our dialysis units since we adopted strategy strict volume control without antihypertensive drugs. The mean observation period was 47 34 (6-140) months. Follow-up ended because death (57 patients), transfer to another center (35 continous ambulatory peritoneal (CAPD) (15 patients) or transplantation (23 while 88 still under treatment at time writing.Blood pressure (BP) decreased from a 150...
Background.Vascular calcification (VC), mainly due to elevated phosphate levels, is one major problem in patients suffering from chronic kidney disease.In clinical studies, an inverse relationship between serum magnesium and VC has been reported.However, there only few information about the influence of on a cellular level available.Therefore, we investigated effect induced by b-glycerophosphate (BGP) bovine vascular smooth muscle cells (BVSMCs).Methods.BVSMCs were incubated with media for...
Background. Longer dialysis sessions may improve outcome in haemodialysis (HD) patients. We compared the clinical and laboratory outcomes of 8- 4-h thrice-weekly HD.
Exposure to high Ca concentrations may influence the development of low–turnover bone disease and coronary artery calcification (CAC) in patients on hemodialysis (HD). In this randomized, controlled study, we investigated effects lowering dialysate level progression CAC histologic abnormalities HD. Patients HD with intact parathyroid hormone levels ≤300 pg/ml receiving containing 1.75 or 1.50 mmol/L ( n =425) were randomized 1.25-mmol/L (1.25 Ca; =212) 1.75-mmol/L (1.75 =213) arm. Primary...
Low serum testosterone levels in hemodialysis (HD) patients have recently been associated with cardiovascular risk factors and increased mortality. To confirm this observation, we investigated the predictive role of total on mortality a large group male HD from Turkey.A 420 prevalent were sampled March 2005 followed up for all-cause Serum measured by ELISA at baseline studied relation to profile.Mean level was 8.69 ± 4.10 (0.17 27.40) nmol/L. A proportion (66%) had deficiency (<10 nmol/L)....
Background. Vascular calcifications are frequent in Stage 5 chronic kidney disease (CKD-5) patients receiving haemodialysis. The current study was designed to evaluate the associations between bone turnover/volume and coronary artery (CAC). Methods. In 207 CKD-5 patients, biopsies, multislice computed tomography of arteries blood drawings for relevant biochemical parameters were done. large number enrolled allowed separate evaluation with CAC versus without adjustment traditional...
Background and objectives End-stage renal disease is linked to alterations in thyroid hormone levels and/or metabolism, resulting a high prevalence of subclinical hypothyroidism low triiodothyronine (T3) levels. These are involved endothelial damage, cardiac abnormalities, inflammation, but the exact mechanisms unclear. In this study, we investigated relationship between serum free-T3 (fT3) carotid artery atherosclerosis, arterial stiffness, vascular calcification prevalent patients on...
Objective Peritoneal fibrosis (PF) is one of the most serious causes failure in continuous ambulatory peritoneal dialysis (PD). Although underlying mechanism responsible for genesis PF still unknown, transforming growth factor p (TGFβ 1 ) has been shown to be associated with PF. Angiotensin converting enzyme inhibitors have prevent stimulating effect factors. The aim present study was investigate enalapril on function and morphology a rat model experimental Methods Twenty-one albino Wistar...
<i>Background:</i> Serum free triiodothyronine (fT3) level is suggested to be a risk factor for mortality in unselected dialysis patients. We investigated the prognostic value of serum fT3 levels and also low-T3 syndrome on overall survival large cohort hemodialysis (HD) patients with normal thyroid-stimulating hormone levels. <i>Methods:</i> A total 669 prevalent HD were enrolled study. was measured by enzyme immune assay frozen sera samples at time enrollment....
Objective: The purpose of this study was to investigate the association neutrophil/lymphocyte ratio and platelet/lymphocyte with clinical outcomes in geriatric patients stage 3–5 chronic kidney disease (CKD).Material Methods: A total 165 over age 65, CKD, were enrolled study. primary endpoints all-cause deaths requirement renal replacement therapy. divided into two groups according delta such as increased (group 1) decreased or stable 2) groups.Results: mean 73.8 ± 6.1 years follow-up 30 13...
Presence of accelerated atherosclerosis in dialysis patients cannot be entirely explained by conventional risk factors. Exposure to urea, which is elevated with kidney disease, leads the carbamylation proteins. We investigated effects carbamylated low-density lipoprotein (cLDL) on human coronary artery vascular smooth muscle cells (VSMC).Native LDL (nLDL) was potassium cyanate. Cells were incubated different concentrations cLDL at time points. Cytotoxicity, apoptosis, proliferation...
Demirci MS, Toz H, Yılmaz F, Ertilav M, Asci G, Ozkahya Zeytinoglu A, Nart D, Ok E. Risk factors and consequences of post‐transplant diabetes mellitus. Clin Transplant 2010 DOI: 10.1111/j.1399‐0012.2010.01247.x. © John Wiley & Sons A/S. Abstract: Background: The aim this study is to investigate the clinical course as well risk prognosis mellitus (PTDM). Methods: Five hundred fifty‐five kidney transplant recipients were retrospectively evaluated. PTDM was defined fasting blood glucose...
The effects of high-flux dialysis and ultrapure dialysate on survival hemodialysis patients are incompletely understood. We conducted a randomized controlled trial to investigate the both membrane permeability purity cardiovascular outcomes. randomly assigned 704 three times per week either high- or low-flux dialyzers standard using two-by-two factorial design. primary outcome was composite fatal nonfatal events during minimum 3 years follow-up. did not detect statistically significant...