A5061958879- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Drug-Induced Ocular Toxicity
- Glaucoma and retinal disorders
- Orthopedic Surgery and Rehabilitation
- Cerebral Venous Sinus Thrombosis
- Peripheral Nerve Disorders
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- Lymphoma Diagnosis and Treatment
- Ophthalmology and Eye Disorders
- Systemic Lupus Erythematosus Research
- Infective Endocarditis Diagnosis and Management
- Retinal and Macular Surgery
- Antimicrobial Resistance in Staphylococcus
- Traumatic Ocular and Foreign Body Injuries
- Syphilis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- IgG4-Related and Inflammatory Diseases
- Otitis Media and Relapsing Polychondritis
- Streptococcal Infections and Treatments
Aintree University Hospitals NHS Foundation Trust
2023-2025
University of Liverpool
2021-2025
Royal Liverpool University Hospital
2021-2023
Aintree University Hospital
2023
St Thomas' Hospital
2021
Babol University of Medical Sciences
2020
Moorfields Eye Hospital
2020
University College London
2020
Norfolk and Norwich University Hospital
2019
James Paget University Hospitals NHS Foundation Trust
2019
Inflammatory adverse events following COVID-19 vaccination are being reported amidst the growing concerns regarding vaccine's immunogenicity and safety, especially in patients with pre-existing inflammatory conditions.Multinational case series of diagnosed an ocular event within 14 days collected from 40 centres over a 3 month period 2021.Seventy presented vaccination. The mean age was 51 years (range, 19-84 years). most common were anterior uveitis (n = 41, 58.6%), followed by posterior 9,...
Introduction Paraneoplastic optic neuropathy (PON) is a rare immune-mediated neuropathy, secondary to an underlying malignancy. This report describes case of bilateral PON as the initial manifestation in 77-year-old male, leading early detection and treatment pre-clinical small cell lung cancer (SCLC). Case Presentation The patient initially presented with incidental disc swelling but was asymptomatic, preserved visual function. Initial investigations, including orbito-cranial imaging,...
Kimura disease (KD) is a rare, chronic, inflammatory condition, predominantly found in male patients of Asian ethnicity. It typically presents between 50–60 years age and usually with bilateral disease. Angiolymphoid hyperplasia eosinophilia (ALHE) remains the main differential diagnosis, although histological analysis essential differentiating from other similarly presenting pathologies. In this case, we present an atypical case unilateral orbital KD middle-aged, Caucasian, gentleman no...
Background: Alport syndrome is an inherited Type IV collagenopathy characterised by renal failure, hearing loss and ophthalmic manifestations such as lenticonus dot-and-fleck retinopathy. New signs have been described which can be useful both for diagnosis prognosticating the risk of complications. This study examines describes a triad comprising unusual ‘stair-case’ foveal sign, together with choroidal thinning late-stage peripheral schisis in patient syndrome. Case presentation: case...
A 64-year-old woman presented with bilateral visual loss shimmering photopsias as the only clinical manifestation of an occult pancreatic ampullary adenocarcinoma causing duct dilatation. Abnormal electroretinograms led to suspicion cancer-associated retinopathy (CAR), and CT abdomen showed underlying malignancy, detected subclinical liver function tests following diagnosis CAR. Biopsy a T2N0M0 adenocarcinoma. The patient was managed Whipple's procedure adjuvant chemotherapy has made good...
Immune checkpoints refer to mechanisms entrusted with the modulation of immune responses in peripheral tissues and are required for minimising collateral damage. checkpoint inhibitors (ICPi) work through numerous pathways, including anti-CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), anti-PD-1 (programmed cell death 1) PD-L1 (protein protein-ligand-1) pathways. They proving be an exciting therapeutic avenue attempt activate anti-tumour activity. Ipilimumab is a fully human monoclonal...
We present a case of presumed topiramate-induced retinopathy in 58-year-old woman who presented with progressive, bilateral visual loss following 3- to 4-year history oral topiramate intake for migraine. She reported difficulty light adaptation, hemeralopia, and color desaturation. Her best-corrected acuity was 1/60 (20/1200) the right eye 6/18 (20/60) left eye, she performed poorly on Ishihara plate testing. Anterior segment examination normal; dilated funduscopy showed mild macular...
A 35-year-old woman presented with a constellation of systemic symptoms: rashes, weight loss, arthralgia and mouth ulcers. Six months afterwards, she experienced bilateral sequential reduction in vision, was found to have vaso-occlusive retinopathy, critical macular ischaemia the left eye. Her serological markers were consistent diagnosis lupus. lymph node biopsy confirmed Kikuchi-Fujimoto disease, benign condition unknown cause characterised by fever, cervical axillary lymphadenopathy....
This report presents the first case of a patient with dual pathogen-associated bioprosthetic aortic valve endocarditis, prosthetic root abscess and multifocal septic emboli, caused by both Trichosporon inkin Cutibacterium acnes. A 67-year-old male replacement, pacemaker presented pyrexia, right arm numbness confusion. Multiple left-sided embolic infarcts were found on brain imaging, eye examination was consistent right-sided fungal endophthalmitis, an vegetation visualised trans-oesophageal...
Despite the current presumption that SARS-CoV-2 is transmitted by droplets, reported evidence of presence virus in air suggests droplets dry fast producing clusters virus, which are most penetrative through commonly available fabric filters to public. We consider corresponding a typical bimodal distribution sneeze and calculate time taken for them evaporate their ultimate size two loadings. The resulting from fine first mode have comparable cigarette smoke. There currently no masks public...
Despite the current presumption that SARS-CoV-2 is transmitted by droplets, reported evidence of presence virus in air suggests droplets dry fast producing clusters virus, which are most penetrative through commonly available fabric filters to public. We consider corresponding a typical bimodal distribution sneeze and calculate time taken for them evaporate their ultimate size two loadings. The resulting from fine first mode have comparable cigarette smoke. There currently no masks public...