- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Systemic Lupus Erythematosus Research
- Advanced Glycation End Products research
- Ocular Infections and Treatments
- Pulmonary Hypertension Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Drug-Induced Ocular Toxicity
- Intracranial Aneurysms: Treatment and Complications
- Hereditary Neurological Disorders
- Kruppel-like factors research
- Ocular Oncology and Treatments
- Cancer-related gene regulation
- Ophthalmology and Eye Disorders
- Peripheral Neuropathies and Disorders
- Teacher Education and Leadership Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Patient-Provider Communication in Healthcare
- Diverse Music Education Insights
- Cerebral Venous Sinus Thrombosis
- Streptococcal Infections and Treatments
- Moyamoya disease diagnosis and treatment
Sichuan University
2025
University of Oxford
2017-2025
East and North Hertfordshire NHS Trust
2025
Lister Hospital
2025
Cambridge University Hospitals NHS Foundation Trust
2020-2024
Norfolk and Norwich University Hospitals NHS Foundation Trust
2024
Tongren University
2022
Addenbrooke's Hospital
2020-2021
Peking University Cancer Hospital
2021
Churchill Hospital
2020
Abstract Adult mammalian central nervous system axons have intrinsically poor regenerative capacity, so axonal injury has permanent consequences. One approach to enhancing regeneration is increase the supply of growth molecules and organelles. We achieved this by expressing adaptor molecule Protrudin which normally found at low levels in non-regenerative neurons. Elevated expression enabled robust both vitro primary cortical neurons vivo injured adult optic nerve. overexpression facilitated...
Abstract Purpose To investigate the impact of central serous chorioretinopathy on sleep and mood in patients with acute chronic chorioretinopathy. Methods This cross-sectional study compared differences between control recruited from Ophthalmology clinics at John Radcliffe Hospital, Oxford 2012 2020. Data including visual acuity, type (acute or chronic; aCSC/cCSC), sex, chronotype were obtained. Sleep quality was measured using Pittsburgh Quality Index (PSQI); Hospital Anxiety Depression...
A 78-year-old man with hypertension and diabetes was referred because of 3 days diplopia ophthalmoplegia. Neurologic examination disclosed exotropia both eyes (wall-eyed) bilateral internuclear ophthalmoplegia (WEBINO) impaired convergence (figure, A).1 Vertical saccades smooth pursuit were also limited, but improved during the …
A 60-year-old man recently admitted for bipedal oedema, endocarditis and a persistently positive COVID-19 swab with history of anticoagulation on rivaroxaban atrial fibrillation, transitional cell carcinoma, cerebral amyloid angiopathy, diabetes hypertension presented sudden onset diplopia vertical gaze palsy. Vestibulo-ocular reflex was preserved. Simultaneously, he developed scotoma visual loss, found to have right branch retinal artery occlusion. MRI head demonstrated unilateral midbrain...
A 64-year-old woman presented with bilateral visual loss shimmering photopsias as the only clinical manifestation of an occult pancreatic ampullary adenocarcinoma causing duct dilatation. Abnormal electroretinograms led to suspicion cancer-associated retinopathy (CAR), and CT abdomen showed underlying malignancy, detected subclinical liver function tests following diagnosis CAR. Biopsy a T2N0M0 adenocarcinoma. The patient was managed Whipple's procedure adjuvant chemotherapy has made good...
We report a modification of pneumatic retinopexy (PnR), incorporating endoillumination, for management recurrent rhegmatogenous retinal detachment (RRD) after scleral buckle (SB). A 42-year-old gentleman underwent SB treatment left-eye RRD without macular involvement and not associated with posterior vitreous detachment. Preoperative best-corrected visual acuity (BCVA) was 6/12 in the left eye. Recurrence noted at 1 month postoperatively, patient elected to undergo modified rescue PnR, where...
To validate the diagnostic performance of a custom 96-micro-organism TaqMan PCR card (iCAM) for microbial keratitis (MK) from single corneal epithelial sample.
A previously fit and well 76-year-old man, presented with distal lower limb sensory symptoms suggestive of peripheral neuropathy, associated positive anti-MAG antibodies (myelin glycoprotein) IgM paraprotein. Bone marrow biopsy showed lymphoplasmocytoid lymphoma (Waldenstrom’s macroglobulinaemia, WM), consequently for MYD88 mutation. He subsequently developed medullary carcinoma the thyroid, most likely secondary to WM. underwent a successful total thyroidectomy four treatment doses...
A 20-year-old female patient was admitted to hospital in 2015 with 1 year history of recurrent abdominal pain, distension, borborygmi and nausea. The had a background systemic lupus erythematous (SLE) diagnosed 4 years before, skin, joint renal involvement. initial investigations have shown long segment ileal inflammation upstream obstruction. Differential diagnoses were mainly SLE enteritis or concomitant Crohn’s. Patient failed the conservative management laparotomy small bowel (SB)...
Pulmonary hypertension (PH) is an underdiagnosed condition associated with poor survival and increased post-operative mortality in lung cancer. CT-based parameters of pulmonary artery enlargement are strong predictors PH. We used these to investigate oesophageal cancer.Consecutive patients cancer (n = 100) or undergoing staging 18F-fluodeoxyglucose PET/CT were retrospectively identified. The transverse diameter the main (mPA) ascending aorta, artery-to-ascending aorta (PA:A) ratio obtained....
The continuous deepening of education and teaching reform urges people to pay more attention the cultivation comprehensive ability music majors, so as better meet needs society for talents. students' not only meets development current era, but also innovation in colleges universities. It has an important impact on personal future employment development. This paper analyzes methods universities from perspective ability, order improve mode courses promote improvement quality ability.
Objective: To evaluate the relationship between anatomical location of intrapulmonary metastatic lymph nodes and relapse risk survival in patients with N1 non-small cell lung cancer(NSCLC). Methods: A retrospective analysis clinical pathological data 138 completely resected NSCLC was conducted. There were 79 males 59 females, aged from 26 to 81 years an average (59±10) years. All them treated Department Thoracic Surgery Ⅱ Peking University Cancer Hospital January 2007 December 2015. Patients...