A5012227928- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Oral microbiology and periodontitis research
- Dental Implant Techniques and Outcomes
- Connective tissue disorders research
- Laser Applications in Dentistry and Medicine
- Periodontal Regeneration and Treatments
- 3D Printing in Biomedical Research
- Mesenchymal stem cell research
- Cardiac Valve Diseases and Treatments
- Epoxy Resin Curing Processes
- Advanced materials and composites
- Proteoglycans and glycosaminoglycans research
- Advanced ceramic materials synthesis
- Dental Trauma and Treatments
- Oral Health Pathology and Treatment
- Cardiac and Coronary Surgery Techniques
- Salivary Gland Disorders and Functions
- Dental Health and Care Utilization
- Dental Research and COVID-19
- Dental Radiography and Imaging
- Drilling and Well Engineering
- Animal testing and alternatives
- Aortic Disease and Treatment Approaches
Saveetha University
2024-2025
Tohoku University
2017-2023
Suzuki (Japan)
2021-2022
Kanagawa Dental University
2020-2022
Tohoku Bunkyo University
2020
Niigata University
2020
Abstract The ultimate goal of periodontal disease treatment is the reorganization functional tissue that can regenerate lost tissue. Regeneration tissues clinically possible by using autogenic transplantation MSCs. However, autologous MSC limited depending on age, systemic and quality, thus precluding their clinical application. Therefore, we evaluated efficacy allogeneic adipose-derived multi-lineage progenitor cells (ADMPC) in a micro-mini pig defect model. ADMPC were isolated from greater...
Abstract We investigated the biofilm removal effects of laser activated irrigation (LAI) using a pig model, focusing on impact fiber tip position, and used high-speed camera to observe occurrence positioning cavitation associated with irradiation. A total 16 roots deciduous mandibular second premolars from 4 pigs were used. After pulpectomy, canals left open for 2 weeks sealed induce intraradicular biofilm. Root canal was then performed Er:YAG activation. The inserted at two different...
ABSTRACT Background Dental composite resins are commonly used due to their excellent physical and mechanical properties. However, exposure beverages like Coca‐Cola, Apple juice, Black coffee can negatively impact these materials. This study examined the effects of drinks on surface microhardness roughness Nanohybrid, Giomer, Dual‐Cure Bulk‐fill resin composites. Methods Seventy‐two disc‐shaped specimens were prepared divided into four groups ( n = 18) based immersion liquid: Group 1...
Introduction Understanding the ion release behaviour of bioactive resin cements is essential for evaluating their potential in restorative dentistry. Sustained release, especially at cariogenic pH levels, can enhance remineralization and prolong longevity dental restorations. This study investigates influence on profiles a cement before after recharging. Methods Disk-shaped specimens ( n = 15) were prepared exposed to three different conditions (4.5, 5.5, 6.5) simulate normal environments....
The treatment of vertical bone defects caused by severe periodontal disease requires the regeneration tissue. Although various substitutes have been clinically applied to defect correction, evaluation these materials in tissue remains incomplete. purpose this study was examine abilities including Cytrans, Cerasorb, Neobone and Bio-Oss a 3-wall animal model. All showed similar healing ability ligament cementum. However, Cytrans fastest compared with other at 4 weeks post-transplantation. In...
Abstract The surface pre‐reacted glass ionomer (S‐PRG) filler, a component of composite resin, is capable releasing metal ions that possess antibacterial activity against caries and periodontal pathogens. Although S‐PRG has been suggested to be involved in oral disease prevention, no reports have published regarding its preventive effect on vivo . present study investigated whether the eluate from (S‐PRG eluate) suppressive tissue destruction induced mouse model ligature‐induced disease....
Abstract Background We established an in vivo intraradicular biofilm model of apical periodontitis pigs which we compared the efficacy different irrigant activation techniques for removal. Methods Twenty roots from deciduous mandibular second premolar 5 male were used. After pulpectomy, canals left open 2 weeks and then sealed 4 to enable development intracanal biofilm. The biofilms was evaluated using SEM bacterial 16S rRNA gene-sequencing. To investigate removal, root canal irrigations...
Bone tissue engineering has been developed using a combination of mesenchymal stem cells (MSCs) and calcium phosphate-based scaffolds. However, these complexes cannot regenerate large jawbone defects. To overcome this limitation MSCs ceramic scaffolds, novel bone regeneration technology must be possessing high forming ability scaffold that provides space for vertical augmentation. approach problem in our study, we alveolar bone-derived immature osteoblast-like (HAOBs), which have the...
Marfan syndrome (MFS) is a systemic disorder of connective tissues caused by insufficient elastic fiber formation that leads to structural weakness and results in various tissue disorders, including cardiovascular periodontal disease. Notably however, the risk disease MFS patients affected an aortic aneurysm or dissection has not yet been clarified.We investigated condition following three groups: diagnosed with planned surgery (MFS surgery), who had already undergone post-surgery) healthy...
Abstract Background Resin-based composites stand as widely employed restorative materials in the field of dentistry, owing to their superior esthetic and physicochemical properties. Nevertheless, a notable limitation these is occurrence polymerization shrinkage, leading stress at interface tooth restoration. Over time, this phenomenon may result marginal leakage secondary caries, thereby causing restoration failure. Objectives Our study aimed conduct comparative evaluation voids, internal...
There is increasing evidence that diagnostic salivary tests measuring inflammatory biomarkers are being developed to assess status for early detection, prevention, and progression of periodontal disease. Therefore, the aim present study was investigate identify biomarker can predict disease.A total 36 patients (28 women 8 men) with an average age 57 years were investigated. Unstimulated saliva collected from recruited subjects analyzed using SillHa, a saliva-testing device measures bacteria...
Abstract Background : We established an in vivo intraradicular biofilm model of apical periodontitis pigs which we compared the efficacy different irrigant activation techniques for removal. Methods Twenty roots from deciduous mandibular second premolar 5 male were used. After pulpectomy, canals left open 2 weeks and then sealed 4 to enable development intracanal biofilm. The biofilms was evaluated using SEM bacterial 16S rRNA gene-sequencing. To investigate removal, root canal irrigations...
Abstract Background Marfan syndrome (MFS) is a systemic disorder of connective tissues caused by insufficient elastic fiber formation that leads to structural weakness and results in various tissue disorders, including cardiovascular periodontal disease. Notably however, the risk disease MFS patients affected an aortic aneurysm or dissection has not yet been clarified. Methods We investigated condition following three groups: diagnosed with planned surgery (MFS surgery), who had already...
Abstract Background We investigated the biofilm removal effects of LAI using a pig model, focusing on impact fiber tip position, and used high-speed camera to observe occurrence positioning cavitation associated with laser irradiation. Methods A total 16 roots deciduous mandibular second premolars from 4 pigs were used. After pulpectomy, canals left open for two weeks sealed induce intraradicular biofilm. Then, root canal irrigation was performed Er:YAG activation. The inserted at different...
Abstract Background We investigated the biofilm removal effects of LAI using a pig model, focusing on impact fiber tip position, and used high-speed camera to observe occurrence positioning cavitation associated with laser irradiation. Methods A total 16 roots deciduous mandibular second premolars from 4 pigs were used. After pulpectomy, canals left open for two weeks sealed induce intraradicular biofilm. Then, root canal irrigation was performed Er:YAG activation. The inserted at different...