A5020810554- Adipose Tissue and Metabolism
- Muscle metabolism and nutrition
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Receptor Mechanisms and Signaling
- Lipid metabolism and biosynthesis
- Thermoregulation and physiological responses
Universidade Estadual de Campinas (UNICAMP)
2017-2025
National Council for Scientific and Technological Development
2022
Susceptibility to obesity differs depending on the genetic background and housing temperatures. We have recently reported that CETP expressing female mice are leaner due increased lipolysis, brown adipose tissue (BAT) activity, body energy expenditure compared nontransgenic (NTg) littermates under standard temperature (22°C). The aim of this study is evaluate how expression affects temperature, composition, metabolism during cold exposure (4°C) thermoneutrality (30°C). When submitted cold,...
ABSTRACT Susceptibility to obesity differs depending on the genetic background and housing temperatures. We have recently reported that CETP expressing female mice are leaner due increased lipolysis, brown adipose tissue (BAT) activity body energy expenditure compared non-transgenic (NTg) littermates under standard temperature (22°C). The aim of this study is evaluate how expression affect temperature, composition metabolism during cold exposure (4°C) thermoneutrality (30°C). When submitted...
Cholesteryl ester transfer protein -CETP -is a plasma that mediates the exchange of triglycerides for esterified cholesterol from HDL to apoB containing lipoproteins.In this way, CETP promotes reduction HDLcholesterol and, thus, increases risk atherosclerosis.Recently, we identified new role CETP, in may modulate adiposity.Previous data our group shows expression reduces adipose tissue mass (~30%) and leptinemia ( 40%), what cannot be explained by differences fat intake or excretion.The...