A5004267751- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Cancer therapeutics and mechanisms
- Advanced X-ray and CT Imaging
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Intensive Care Unit Cognitive Disorders
- Delphi Technique in Research
- Viral gastroenteritis research and epidemiology
- Telemedicine and Telehealth Implementation
- Neurogenetic and Muscular Disorders Research
- Immune responses and vaccinations
- Zoonotic diseases and public health
- Veterinary Orthopedics and Neurology
- Head and Neck Cancer Studies
- Cardiovascular Disease and Adiposity
- PI3K/AKT/mTOR signaling in cancer
- Thyroid Disorders and Treatments
- Respiratory and Cough-Related Research
- Thermal Regulation in Medicine
- Phonetics and Phonology Research
University of Nottingham
2021-2024
Nottingham University Hospitals NHS Trust
2019-2023
Queen's Medical Centre
2019-2023
RELX Group (Netherlands)
2023
Denver Health Medical Center
2021
University of Colorado Denver
2021
University of Manchester
2020
The Christie NHS Foundation Trust
2018
Hoosier Cancer Research Network (United States)
2006-2008
Indiana University – Purdue University Indianapolis
1991-2007
The COVID-19 pandemic and the UK government's subsequent coronavirus action plan have fundamentally impacted on every aspect of healthcare. One area that is severely affected ear, nose throat (ENT)/laryngology where speech language therapists (SLTs) engage in a diverse range practice with patients conditions, including voice disorders, airway problems, head neck cancers (HNCs). A large majority these are high-risk categories, many specialized clinical practices vulnerable. In addition,...
Abstract Background Management of benign vocal fold lesions (BVFLs) is variable with individuals receiving surgery, voice therapy, or a combination these approaches. Some evidence suggests that the best outcomes may be achieved when patients are offered pre- and post-operative therapy in addition to phonosurgery, but what constitutes poorly described. The (PAPOV) intervention has been developed described according TIDieR checklist Rehabilitation Treatment Specification System (RTSS) for...
7043 Background: Concurrent chemo radiotherapy is the standard treatment for pts with unresectable stage III NSCLC. A previously reported phase II study (Gandara et al J Clin Oncol 2003) suggests that consolidation D after concurrent PE/XRT may further improve survival. HOG LUN01–24, an ongoing clinical trial comparing radiation. preliminary analysis of differences in toxicities between or without was performed. Methods: Eligible had untreated, NSCLC, ECOG PS 0–1 at time entry (and 0–2...
Abstract Background Muscle tension dysphonia (MTD) results from inefficient or ineffective voice production and is the cause of throat complaints in up to 40% patients presenting with hoarseness. Standard treatment therapy (SLT-VT) delivered by specialist speech therapists disorders (SLT-V). The Complete Vocal Technique (CVT) a structured, pedagogic method which helps healthy singers other performers optimise their vocal function enabling them produce any sound required. aim this feasibility...
7063 Background: Patients with relapsed SCLC have a dismal prognosis. Pemetrexed is well tolerated agent, which active against non-small cell lung cancer. We postulated that may also be and in pts SCLC, for whom few effective options exist. Methods: Eligible had small or poorly differentiated neuroendocrine cancer, received 1 2 prior chemotherapy regimens an ECOG PS 0–2. Pts 500 mg/m iv once every 3 weeks along vitamin B 12 , folic acid, dexamethasone up to 6 cycles progressive disease...
Abstract ARRY-380 is an orally active, potent small molecule tyrosine kinase inhibitor targeting ErbB2. The compound a reversible, ATP-competitive with nanomolar potency against ErbB2 in both vitro and cell-based assays. This has very good vivo PK/ADME properties shown excellent activity numerous mouse tumor models including breast (BT-474, MDA-MB-453), ovarian (SKOV-3) gastric (N87) carcinoma models. Here we demonstrate single agent combinability trastuzumab, docetaxel or bevacizumab For...
Abstract Background: Management of benign vocal fold lesions (BVFLs) is variable with some receiving surgery, voice therapy or a combination these approaches. Some evidence suggests that the best outcomes may be achieved when patients are offered pre and post-operative in addition to phonosurgery, but what constitutes poorly described. The (PaPOV) intervention has been developed described according TiDIER checklist Rehabilitation Treatment Specification System for voice. PaPOV delivered by...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
7668 Background: Concurrent chemoradiation is standard treatment against stage III NSCLC. HOG LUN 01–24 examines whether consolidation therapy with D improves overall survival. We present an analysis investigating the association of patient characteristics survival from patients on this study. Methods: Eligible had untreated NSCLC, FEV1 ≥ 1 liter, PS 0–1, and weight loss < 5%. Patients received P 50 mg/m 2 days 1, 8, 29, 36 E 1–5, 29–33, concurrent 5,940 cGy XRT. non-progressive disease...
<h3>Objective</h3> To investigate whether cardiac magnetic resonance (CMR) can assess the progression and regression of myocardial fibrosis in patients with aortic stenosis (AS). <h3>Methods</h3> Sixty-three were followed up for 2 years serial CMR echocardiography: 28 (63±13 years, 68% male, 50% asymptomatic severe AS) did not undergo intervention (<i>natural history cohort</i>) 35 (67±8 73% 83% symptomatic underwent valve replacement (AVR) within first year (<i>AVR cohort</i>). Replacement...